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公开(公告)号:US20180265832A1
公开(公告)日:2018-09-20
申请号:US15764036
申请日:2016-10-19
Applicant: Rohto Pharmaceutical Co., Ltd.
Inventor: Tetsuo Koike , Masahiro Takimoto , Yoshiki Yagi
Abstract: Provided is a cell treatment apparatus that includes: an isolator that has an inner space maintained in aseptic conditions and is configured to treat cells in the inner space; trays and that are each configured to house plural kinds of articles, which include reagent containers with articles and reagents therein for use in treatment of cells in the inner space of the isolator, while positioning them; and pass boxes that are configured to respectively carry the trays with the plural kinds of articles housed therein into the isolator.
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公开(公告)号:US20180290136A1
公开(公告)日:2018-10-11
申请号:US15764731
申请日:2016-10-19
Applicant: Rohto Pharmaceutical Co., Ltd.
Inventor: Tetsuo Koike , Masahiro Takimoto , Yoshiki Yagi
Abstract: Provided is a cell treatment apparatus that includes: an isolator; a disposal box that includes a storage part; and a decontamination unit, wherein the disposal box includes: a first opening and closing device that is configured to allow the isolator and the storage part to be communicated with each other at the time of disposal of the waste product and allow them to be shut off from each other after the putting-in of the waste product and before the disposal of the same; and a second opening and closing device that is configured to allow the storage part and the outside to be communicated with each other at the time of disposal of the waste product, which has been put into the storage part, and allow them to be shut off from each other after the disposal of the waste product.
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公开(公告)号:US20180072980A1
公开(公告)日:2018-03-15
申请号:US15553872
申请日:2016-03-03
Applicant: Rohto Pharmaceutical Co., Ltd.
Inventor: Tetsuo Koike , Masahiro Takimoto , Yoshiki Yagi
CPC classification number: C12M41/36 , C12M1/00 , C12M1/34 , C12M1/36 , C12M3/02 , C12M41/46 , C12M41/48 , C12N5/06 , C12R1/91 , G06T1/0014
Abstract: Provided is an apparatus to produce cultured cell products including: an isolator configured to maintain its inside in aseptic conditions and process cell culture vessels therein; and at least one robot arm located within the isolator, wherein a taking-out step of taking out cells cultured in the cell culture vessels, a cell density-adjusting step of adjusting density of the cells in a cell-containing liquid containing the taken-out cells, and a subdividing step of subdividing and placing the cell-containing liquid with its density adjusted into a plurality of product containers are performed within the isolator by the at least one robot arm.
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公开(公告)号:US11273437B2
公开(公告)日:2022-03-15
申请号:US15764731
申请日:2016-10-19
Applicant: Rohto Pharmaceutical Co., Ltd.
Inventor: Tetsuo Koike , Masahiro Takimoto , Yoshiki Yagi
Abstract: Provided is a cell treatment apparatus that includes: an isolator; a disposal box that includes a storage part; and a decontamination unit, wherein the disposal box includes: a first opening and closing device that is configured to allow the isolator and the storage part to be communicated with each other at the time of disposal of the waste product and allow them to be shut off from each other after the putting-in of the waste product and before the disposal of the same; and a second opening and closing device that is configured to allow the storage part and the outside to be communicated with each other at the time of disposal of the waste product, which has been put into the storage part, and allow them to be shut off from each other after the disposal of the waste product.
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公开(公告)号:US20190119621A1
公开(公告)日:2019-04-25
申请号:US15766194
申请日:2016-10-19
Applicant: Rohto Pharmaceutical Co., Ltd.
Inventor: Tetsuo Koike , Masahiro Takimoto , Yoshiki Yagi
Abstract: Provided is a cell treatment apparatus including a treatment chamber that is configured to secure a space for arranging therein a plurality of containers for use in treatment of cells in an inner space maintained in aseptic conditions, a gripping mechanism that is arranged in the treatment chamber and is configured to grip the plurality of containers arranged in the space, wherein the plurality of containers are capable of being arranged in the space so as to have their positions matched with predetermined positions of the plurality of containers so that the gripping mechanism can grip a container to be selected based on a command from among the plurality of containers.
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公开(公告)号:US20180282681A1
公开(公告)日:2018-10-04
申请号:US15764779
申请日:2016-10-19
Applicant: Rohto Pharmaceutical Co., Ltd.
Inventor: Tetsuo Koike , Masahiro Takimoto , Yoshiki Yagi
Abstract: A cell treatment apparatus includes: a treatment chamber that is configured to treat cells; trays that are each configured to house containers for use in the treatment of cells in the treatment chamber, while positioning them; a gripping mechanism that is configured to grip and move at least one kind of the containers housed in each of the trays within the treatment chamber; and a container correct/incorrect determining apparatus that includes a storage device that is configured to prestore given postures of the containers relative to the each corresponding tray, an imaging device that is configured to image the containers arranged in the tray, and a determining device that is configured to determine whether the postures of the containers relative to the tray that are stored in the storage device are matched with postures of the containers relative to the tray that have been imaged by the imaging device.
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公开(公告)号:US20180066218A1
公开(公告)日:2018-03-08
申请号:US15553847
申请日:2016-03-03
Applicant: Rohto Pharmaceutical Co., Ltd.
Inventor: Tetsuo Koike , Masahiro Takimoto , Yoshiki Yagi
CPC classification number: C12M1/32 , B25J15/08 , B25J18/007 , C12M3/00 , C12M23/38 , C12M23/44 , C12M23/50 , C12M33/10 , C12M37/00 , C12M41/14 , C12M41/36 , C12M41/48
Abstract: Provided is an apparatus to produce cultured cell products including: an incubator configured to house cell culture vessels; an isolator configured to process the cell culture vessels conveyed from the incubator; and a pass box capable of carrying, into the isolator, articles and reagents, wherein the isolator includes: an observation section including first robot arms configured to move the cell culture vessels to an observation position so as to check the degree of growth of the cells in the cell culture vessels taken out of the incubator; a processing section including second robot arms configured to perform various processes to transfer the cells in the cell culture vessels that have a specified number of cells into product containers; and an outlet configured to allow a large number of product containers into which the cells have been transferred to be taken out therethrough.
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