Evaporator for a refrigeration device
    5.
    发明申请
    Evaporator for a refrigeration device 审中-公开
    蒸发器用于制冷装置

    公开(公告)号:US20050138959A1

    公开(公告)日:2005-06-30

    申请号:US11017614

    申请日:2004-12-20

    CPC分类号: F25B39/02 F25B47/006

    摘要: The evaporator for a refrigeration device includes a hydrophobic coating on the surface thereof to inhibit the icing of the evaporator during operation and to reduce the generation of noises arising from relative displacements between the evaporator and the ice attached thereto. The evaporator is a lamellar evaporator and has a pipeline through which a refrigerant flows and a surface in thermally conductive contact with the pipeline. The surface is a heat-exchange surface and has a hydrophobic layer of oil thereon.

    摘要翻译: 用于制冷装置的蒸发器包括在其表面上的疏水涂层,以在操作期间抑制蒸发器的结冰并且减少由于蒸发器和附着在其上的冰之间的相对位移而产生的噪声。 蒸发器是层状蒸发器,并且具有制冷剂流经的管道和与管道导热接触的表面。 表面是热交换表面,并且在其上具有疏水层的油。

    Cephalosporins
    9.
    发明授权
    Cephalosporins 失效
    头孢菌素

    公开(公告)号:US4364944A

    公开(公告)日:1982-12-21

    申请号:US323382

    申请日:1981-11-20

    CPC分类号: C07D501/20 Y02P20/55

    摘要: Compounds of the formula ##STR1## wherein Y is hydrogen or methoxy;A is ##STR2## or, when Y is methoxy, also phenyl, 4-hydroxy-phenyl, 2-thienyl, 3-thienyl of 3,4-dihydroxy-phenyl;A' is hydrogen, --COCH.sub.2 Cl, --COCH.sub.2 Br, --COOCH.sub.2 CCL.sub.3, formyl or trityl;D is hydrogen, acetoxy, aminocarbonyloxy, pyridinium, 4-aminocarbonyl-pyridinium or -S-Het, where Het is 3-methyl-1,2,4-thiadiazol-5-yl, 1,2,4-thiadiazol-5-yl, 1,3,4-thiadiazol-5-yl, 2-methyl-1,3,4-thiadiazol-5-yl, 4H-5,6-dioxo-1,2,4-triazine-3-yl, 4-methyl-5,6-dioxo-1,2,4-triazin-3-yl, 1-vinyl-tetrazol-5-yl, 1-allyl-tetrazol-5-yl or ##STR3## n is 1, 2 or 3; R.sub.1 is hydroxyl, amino, dimethylamino, acetylamino, aminocarbonyl, aminocarbonylamino, aminosulfonyl, aminosulfonylamino, methylcarbonyl, methylsulfonylamino, cyano, hydroxysulfonylamino, methylsulfonyl, methylsulfinyl, a carboxylic acid group or a sulfonic acid group; or--(CH.sub.2).sub.n R.sub.1 is alkyl of 1 to 4 carbon atoms or 2,3-dihydroxy-propyl;R.sub.2 is unsubstituted or monosubstituted 3-pyridyl, 5-pyrimidinyl, 2-thienyl, 2-furyl-methyl, 2-thienyl-methyl, 2-imidazolyl-methyl, 2-thiazolyl-methyl, 3-pyridyl-methyl or 5-pyrimidinyl-methyl, where the substituent is chlorine, methyl, acetylamino, hydroxyl, methylsulfinyl, methylsulfonyl, aminocarbonyl or aminosulfonyl; andE is hydrogen or a carboxyl-protective group which is easily removable in vitro or in vivo;and, E is hydrogen, non-toxic, pharmacologically acceptable salts thereof formed with inorganic or organic bases; the compounds as well as their salts are useful as antibiotics.

    摘要翻译: 其中Y是氢或甲氧基的式“IMAGE”的化合物; A是,或者当Y是甲氧基时,3,4-二羟基 - 苯基的苯基,4-羟基 - 苯基,2-噻吩基,3-噻吩基; A'是氢,-COCH 2 Cl,-COCH 2 Br,-COOCH 2 CCl 3,甲酰基或三苯甲基; D是氢,乙酰氧基,氨基羰氧基,吡啶鎓,4-氨基羰基 - 吡啶鎓或-S-Het,其中Het是3-甲基-1,2,4-噻二唑-5-基,1,2,4-噻二唑-5-基, 1,3,4-噻二唑-5-基,2-甲基-1,3,4-噻二唑-5-基,4H-5,6-二氧代-1,2,4-三嗪-3-基, 4-甲基-5,6-二氧代-1,2,4-三嗪-3-基,1-乙烯基 - 四唑-5-基,1-烯丙基 - 四唑-5-基或n为1,2 或3; R1是羟基,氨基,二甲基氨基,乙酰基氨基,氨基羰基,氨基羰基氨基,氨基磺酰基,氨基磺酰基氨基,甲基羰基,甲基磺酰基氨基,氰基,羟基磺酰基氨基,甲基磺酰基,甲基亚磺酰基,羧酸基或磺酸基团。 或 - (CH 2)n R 1是1至4个碳原子的烷基或2,3-二羟基 - 丙基; R2是未取代的或单取代的3-吡啶基,5-嘧啶基,2-噻吩基,2-呋喃基 - 甲基,2-噻吩基 - 甲基,2-咪唑基 - 甲基,2-噻唑基 - 甲基,3-吡啶基 - 甲基或5-嘧啶基 甲基,其中取代基是氯,甲基,乙酰氨基,羟基,甲基亚磺酰基,甲基磺酰基,氨基羰基或氨基磺酰基; E是氢或羧基保护基,其在体外或体内容易除去; 和E是氢,与无机或有机碱形成的无毒的药理学上可接受的盐; 化合物及其盐可用作抗生素。