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公开(公告)号:US08933042B2
公开(公告)日:2015-01-13
申请号:US11992091
申请日:2006-09-18
申请人: Romaan Raemaekers , Pascale Feldmann , Geert Plaetinck , Irene Nooren , Els Van Bleu , Frederic Pecqueur , Laurent Kubler , Nicole Damme , Lies Degrave , Isabel Remory
发明人: Romaan Raemaekers , Pascale Feldmann , Geert Plaetinck , Irene Nooren , Els Van Bleu , Frederic Pecqueur , Laurent Kubler , Nicole Damme , Lies Degrave , Isabel Remory
CPC分类号: C12N15/113 , A01N63/02 , C12N15/8286 , C12N2310/14 , Y02A40/162
摘要: The present invention relates to methods for controlling pest infestation using double stranded RNA molecules. The invention provides methods for producing transgenic cells expressing the double stranded RNA molecules, as well as compositions and commodity products containing or treated with such molecules.
摘要翻译: 本发明涉及使用双链RNA分子控制害虫侵染的方法。 本发明提供了用于产生表达双链RNA分子的转基因细胞的方法,以及含有或用这些分子处理的组合物和商品。
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公开(公告)号:US20090306189A1
公开(公告)日:2009-12-10
申请号:US11992091
申请日:2006-09-18
申请人: Romaan Raemaekers , Pascale Feldmann , Geert Plaetinck , Irene Nooren , Els Van Bleu , Frederic Pecqueur , Laurent Kubler , Nicole Damme , Lies Degrave , Isabel Remory
发明人: Romaan Raemaekers , Pascale Feldmann , Geert Plaetinck , Irene Nooren , Els Van Bleu , Frederic Pecqueur , Laurent Kubler , Nicole Damme , Lies Degrave , Isabel Remory
IPC分类号: A61K31/7105 , A01N43/34 , C07H21/02 , C07H21/04 , C12N1/21 , C12N1/13 , A61K31/711 , C12N1/19 , A61P31/04 , A01P17/00 , A23L1/48
CPC分类号: C12N15/113 , A01N63/02 , C12N15/8286 , C12N2310/14 , Y02A40/162
摘要: The present invention relates to methods for controlling pest infestation using double stranded RNA molecules. The invention provides methods for producing transgenic cells expressing the double stranded RNA molecules, as well as compositions and commodity products containing or treated with such molecules.
摘要翻译: 本发明涉及使用双链RNA分子控制害虫侵染的方法。 本发明提供了用于产生表达双链RNA分子的转基因细胞的方法,以及含有或用这些分子处理的组合物和商品。
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公开(公告)号:US09982258B2
公开(公告)日:2018-05-29
申请号:US14485103
申请日:2014-09-12
申请人: Romaan Raemaekers , Pascale Feldmann , Geert Plaetinck , Irene Nooren , Frederic Pecqueur , Laurent Kubler , Nicole Damme , Lies Degrave , Isabel Remory , Thierry Bogaert
发明人: Romaan Raemaekers , Pascale Feldmann , Geert Plaetinck , Irene Nooren , Els Van Bleu , Frederic Pecqueur , Laurent Kubler , Nicole Damme , Lies Degrave , Isabel Remory , Thierry Bogaert
IPC分类号: C12N15/11 , C12N15/113 , A01N63/02 , C12N15/82
CPC分类号: C12N15/113 , A01N63/02 , C12N15/8286 , C12N2310/14 , Y02A40/162
摘要: The present invention relates to methods for controlling pest infestation using double stranded RNA molecules. The invention provides methods for producing transgenic cells expressing the double stranded RNA molecules, as well as compositions and commodity products containing or treated with such molecules.
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公开(公告)号:US08906876B2
公开(公告)日:2014-12-09
申请号:US13592513
申请日:2012-08-23
申请人: Romaan Raemaekers , Laurent Kubler , Geert Karel Maria Plaetinck , Els Vanbleu , Thierry Andre Olivier Eddy Bogaert
发明人: Romaan Raemaekers , Laurent Kubler , Geert Karel Maria Plaetinck , Els Vanbleu , Thierry Andre Olivier Eddy Bogaert
CPC分类号: C07K14/43563 , A01N57/16 , A01N63/00 , A01N63/02 , A01N63/04 , A61K38/00 , C12N15/8218 , C12N15/8286 , Y02A40/162 , A01N25/00 , A01N2300/00
摘要: The present invention concerns methods for controlling insect infestation via RNAi-mediated gene silencing, whereby the intact insect cell(s) are contacted with a double-stranded RNA from outside the insect cell(s) and whereby the double-stranded RNA is taken up by the intact insect cell(s). In one particular embodiment, the methods of the invention are used to alleviate plants from insect pests. Alternatively, the methods are used for treating and/or preventing insect infestation on a substrate or a subject in need of such treatment and/or prevention. Suitable insect target genes and fragments thereof, dsRNA constructs, recombinant constructs and compositions are disclosed.
摘要翻译: 本发明涉及通过RNAi介导的基因沉默来控制昆虫侵袭的方法,其中完整的昆虫细胞与来自昆虫细胞外的双链RNA接触,由此将双链RNA吸收 通过完整的昆虫细胞。 在一个具体实施方案中,本发明的方法用于减轻植物害虫。 或者,所述方法用于治疗和/或预防对需要这种治疗和/或预防的基质或受试者的昆虫侵袭。 公开了合适的昆虫靶基因及其片段,dsRNA构建体,重组构建体和组合物。
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公开(公告)号:US20130058890A1
公开(公告)日:2013-03-07
申请号:US13592513
申请日:2012-08-23
申请人: Romaan Raemaekers , Laurent Kubler , Geert Karel Maria Plaetinck , Els Vanbleu , Thierry Andre Olivier Eddy Bogaert
发明人: Romaan Raemaekers , Laurent Kubler , Geert Karel Maria Plaetinck , Els Vanbleu , Thierry Andre Olivier Eddy Bogaert
IPC分类号: A01N63/04 , A61K35/74 , A61K36/06 , A01M1/20 , C12N1/19 , C07H21/04 , A01P21/00 , A01N63/02 , A01N25/00 , C12N1/21
CPC分类号: C07K14/43563 , A01N57/16 , A01N63/00 , A01N63/02 , A01N63/04 , A61K38/00 , C12N15/8218 , C12N15/8286 , Y02A40/162 , A01N25/00 , A01N2300/00
摘要: The present invention concerns methods for controlling insect infestation via RNAi-mediated gene silencing, whereby the intact insect cell(s) are contacted with a double-stranded RNA from outside the insect cell(s) and whereby the double-stranded RNA is taken up by the intact insect cell(s). In one particular embodiment, the methods of the invention are used to alleviate plants from insect pests. Alternatively, the methods are used for treating and/or preventing insect infestation on a substrate or a subject in need of such treatment and/or prevention. Suitable insect target genes and fragments thereof, dsRNA constructs, recombinant constructs and compositions are disclosed.
摘要翻译: 本发明涉及通过RNAi介导的基因沉默来控制昆虫侵袭的方法,其中完整的昆虫细胞与来自昆虫细胞外的双链RNA接触,由此将双链RNA吸收 通过完整的昆虫细胞。 在一个具体实施方案中,本发明的方法用于减轻植物害虫。 或者,所述方法用于治疗和/或预防对需要这种治疗和/或预防的基质或受试者的昆虫侵袭。 公开了合适的昆虫靶基因及其片段,dsRNA构建体,重组构建体和组合物。
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公开(公告)号:US20090298787A1
公开(公告)日:2009-12-03
申请号:US12087536
申请日:2007-01-12
申请人: Romaan Raemaekers , Laurent Kubler , Els Vanbleu
发明人: Romaan Raemaekers , Laurent Kubler , Els Vanbleu
IPC分类号: A61K31/7105 , C12N15/11 , C12N5/04 , A01H5/00 , C12N15/82
CPC分类号: C12N15/8286 , A01N57/16 , A01N61/00 , C07K14/43527 , C07K14/4354 , C12N15/113 , C12N15/8282 , C12N15/8285 , C12N2310/14 , Y02A40/162 , Y02A40/164
摘要: The present invention relates to methods for controlling pest infestation using double standard RNA molecules. The invention provides methods for making transgenic plants that express the double stranded RNA molecules, as well as pesticidal agents and commodity products produced by the inventive plants.
摘要翻译: 本发明涉及使用双标准RNA分子控制害虫侵染的方法。 本发明提供了用于制备表达双链RNA分子的转基因植物以及由本发明植物产生的杀虫剂和商品的方法。
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公开(公告)号:US20090285784A1
公开(公告)日:2009-11-19
申请号:US12087537
申请日:2007-01-12
IPC分类号: A01N57/16 , C07H21/04 , C07H21/02 , C12N1/21 , C12N1/19 , C12N1/13 , A01N63/00 , A01P7/04 , A61K31/713
CPC分类号: C12N15/8286 , A01N57/16 , A01N61/00 , C07K14/43527 , C07K14/4354 , C12N15/8282 , C12N15/8285 , Y02A40/162 , Y02A40/164
摘要: The present invention concerns methods for controlling insect infestation via RNAi-mediated gene silencing, whereby the intact insect cell(s) are contacted with a double-stranded RNA from outside the insect cell(s) and whereby the double-stranded RNA is taken up by the intact insect cell(s). In one particular embodiment, the methods of the invention are used to alleviate plants from insect pests. Alternatively, the methods are used for treating and/or preventing insect infestation on a substrate or a subject in need of such treatment and/or prevention. Suitable insect target genes and fragments thereof, dsRNA constructs, recombinant constructs and compositions are disclosed.
摘要翻译: 本发明涉及通过RNAi介导的基因沉默来控制昆虫侵袭的方法,其中完整的昆虫细胞与来自昆虫细胞外的双链RNA接触,由此将双链RNA吸收 通过完整的昆虫细胞。 在一个具体实施方案中,本发明的方法用于减轻植物害虫。 或者,所述方法用于治疗和/或预防对需要这种治疗和/或预防的基质或受试者的昆虫侵袭。 公开了合适的昆虫靶基因及其片段,dsRNA构建体,重组构建体和组合物。
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