公开(公告)号：US07887532B2

公开(公告)日：2011-02-15

申请号：US11469902

申请日：2006-09-05

申请人： Ronald M. Kurtz ,  Francis W. Price, Jr. ,  Melvin Sarayba

发明人： Ronald M. Kurtz ,  Francis W. Price, Jr. ,  Melvin Sarayba

IPC分类号： A61B18/20

CPC分类号： A61F9/008 ,  A61F9/00831 ,  A61F2009/00872 ,  A61F2009/00897

摘要： A system and method for resecting corneal tissue is disclosed. A resection pattern is selected for resecting corneal tissue. The resection pattern is incised in a cornea using a surgical laser, leaving one or more uncut gaps in the incised resection pattern. Any uncut gaps left in the resection pattern may thereafter be incised using an alternate surgical instrument.

摘要翻译： 公开了一种用于切除角膜组织的系统和方法。 选择切除图案以切除角膜组织。 使用手术激光切割角膜切除图案，在切开切除图案中留下一个或多个未切割的间隙。 切除图案中残留的任何未切割的间隙可以随后使用替代手术器械切开。

公开(公告)号：US5171213A

公开(公告)日：1992-12-15

申请号：US744875

申请日：1991-08-14

申请人： Francis W. Price, Jr.

发明人： Francis W. Price, Jr.

IPC分类号： A61F9/007 ,  A61M1/00

CPC分类号： A61F9/00781 ,  Y10S623/905

摘要： A technique and device for relieving intraocular pressure within the eye with a reduced risk of inflammation that may be caused by the retrograde flow of fluid and inflammatory debris back into the eye after a glaucoma surgical procedure has been performed. A unidirectional drainage device is implanted to drain fluids away from the eye. The device allows fluid flow away from the eye with a minimal pressure gradient (5 mm Hg. or less), and includes means to prevent retrograde flow. At the time of implantation, the drainage passageway is initially restricted or closed by a flow restrictor at a point downstream from the minimal pressure gradient unidirectional valve. Between the unidirectional valve and flow restrictor is a drainage trap in which debris is receivable without restricting the operativeness of the unidirectional valve. After sufficient scarring and fibrosis has occurred to prevent excessive drainage that might cause hypotony, the flow restrictor is removed to allow the free flow of fluid away from the eye, with inflammatory debris being prevented from reentering the eye. In a second embodiment, the flow restrictor is located at the distal end of the receptor tube of the device within the eye, and acts to prevent the influx of fluids into the device from the eye during the initial period after implantation. Upon removal of the flow restrictor, the free flow of fluids away from the eye is allowed while retrograde flow back into the eye is prevented by the unidirectional valve.

摘要翻译： 一种用于在眼睛内缓解眼内压的技术和装置，其具有降低的炎症风险，这可能是由于在进行青光眼外科手术后流体和炎症性碎屑逆行流入眼睛而引起的。 植入单向引流装置以将流体从眼睛排出。 该装置允许流体以最小的压力梯度（5mmHg或更小）离开眼睛，并且包括防止逆行流动的装置。 在植入时，排水通道在最小压力梯度单向阀下游的点处由限流器开始受到限制或关闭。 在单向阀和限流器之间是排水阀，其中可以接收碎屑而不限制单向阀的操作性。 在发生足够的瘢痕形成和纤维化以防止可能引起低血压的过度引流之后，除去流量限制器以允许流体自由流动离开眼睛，防止炎症碎屑重新进入眼睛。 在第二实施例中，流量限制器位于眼睛内的装置的受体管的远端，并且用于防止在植入之后的初始阶段流体从眼睛流入装置中。 在去除限流器时，允许离开眼睛的流体的自由流动，而通过单向阀可以防止逆流回到眼睛。

公开(公告)号：US4750904A

公开(公告)日：1988-06-14

申请号：US846705

申请日：1986-03-31

申请人： Francis W. Price, Jr.

发明人： Francis W. Price, Jr.

IPC分类号： A61F2/16

CPC分类号： A61F2/161 ,  A61F2/16 ,  A61F2/1608 ,  A61F2002/1683

摘要： A posterior chamber intraocular lens implant having improved fixation where there is no posterior capsule remaining to serve as a fixation platform. In addition to ciliary sulcus haptics, the lens implant has two oppositely disposed loops which serve as suture sites for the suturing of the implant directly to the iris. The loops, which are only so large so as to accommodate a 9-0 size suture thread, extend anteriorly from the optical lens to act as a cushion between the lens and the iris of the eye, and radially such that they align with the striae of the iris when the implant has been positioned within the eye, whereby inflamation of the iris is minimized.

摘要翻译： 具有改善的固定的后室人工晶状体植入物，其中没有后囊保留用作固定平台。 除了睫状沟襻，透镜植入物具有两个相对设置的环，其用作用于将植入物直接缝合到虹膜的缝合部位。 只有这样大的环才能容纳9-0尺寸的缝合线，从光学透镜向前延伸，作为透镜和眼睛虹膜之间的缓冲垫，并且径向地使它们与条纹对齐 当植入物已经定位在眼睛内时，虹膜的炎症被最小化。

公开(公告)号：US5334213A

公开(公告)日：1994-08-02

申请号：US137908

申请日：1993-10-15

申请人： Francis W. Price, Jr.

发明人： Francis W. Price, Jr.

IPC分类号： A61F2/14 ,  A61F9/00 ,  A61B17/32

CPC分类号： A61F9/00 ,  A61B17/32053 ,  A61F2/14 ,  A61F2/142 ,  A61F9/013 ,  A61F9/0133 ,  A61B2017/00969

摘要： A corneal press is disclosed for accurately trephining corneal tissue. The disclosed press includes a base support member, a modular cutting block, two guide posts, a collet mount, a threaded drive mechanism, and a set of modular collets. The base includes means for securely holding the cutting block in position for holding a corneal specimen to be cut about a defined axis. The guide posts are attached to the base in offset parallel alignment relative to the defined axis. The collet mount is mounted onto the guide posts and is slidable relative thereto toward and away from a corneal specimen positioned on the cutting block mounted onto the base. The threaded drive mechanically links the collet mount to the base such that the operation of the threaded drive causes the collet mount to move along said guide posts toward or away from a specimen positioned on the base. Each of a set of modular collets are mountable to the collet mount and are configured to securely hold a trephine of a specifically defined diameter in centered alignment about the defined axis. When so positioned for a cutting operation, the operation of the threaded drive causes the trephine to move along the defined axis and to precisely cut a specimen of corneal tissue positioned on the base about said axis. An alignment sight hole, which extends through collet mount in alignment with said defined axis and which is co-aligned with a sight hole extending a collet mounted therein, allows for the visual alignment of the cut to be made and also provides a means for directing illumination onto the cutting area during a cutting procedure.

摘要翻译： 公开了一种角膜压片机用于精确地植入角膜组织。 所公开的压力机包括基部支撑构件，模块化切割块，两个引导柱，夹头安装件，螺纹驱动机构和一组模块化夹头。 基座包括用于将切割块牢固地保持在适当位置以保持围绕限定轴线切割的角膜样本的装置。 引导柱相对于限定的轴线以偏移平行对准的方式附接到基座。 夹头安装件安装在引导柱上，并且可相对于其移动并朝向位于安装在基座上的切割块上的角膜样本滑动。 螺纹驱动器将夹头安装件机械连接到基座，使得螺纹驱动器的操作使得夹头安装件沿着所述引导柱朝向或远离位于基座上的试样移动。 一组模块夹头中的每一个可安装到夹头安装件上，并且构造成以围绕限定的轴线居中对齐的方式牢固地保持具体限定的直径的环管。 当如此定位用于切割操作时，螺纹驱动器的操作使得环钻沿着限定的轴线移动并且精确地切割位于围绕所述轴线的基座上的角膜组织的样本。 对准瞄准孔，其延伸穿过与所述限定的轴线对准的夹头安装件，并且与安装在其中的夹头延伸的瞄准孔共同对准，允许要进行切割的视觉对准，并且还提供用于引导的装置 在切割过程中照明到切割区域。

公开(公告)号：US5326345A

公开(公告)日：1994-07-05

申请号：US971072

申请日：1992-11-03

申请人： Francis W. Price, Jr.

发明人： Francis W. Price, Jr.

IPC分类号： A61F9/007 ,  A61F2/14 ,  A61M5/00 ,  A61M35/00

CPC分类号： A61F9/00781

摘要： A technique and device for relieving intraocular pressure with a reduced risk of inflammation that may be caused by retrograde flow back into the eye. A unidirectional drainage device is implanted which allows fluid to flow away from the eye with a minimal pressure gradient (5 mm Hg. or less), and includes means to prevent retrograde flow. When implanted, the drainage passageway is initially restricted by a flow restrictor. After fibrosis has occurred to prevent excessive drainage that might cause hypotony, the flow restrictor is severed to allow the free flow of fluid away from the eye, with inflammatory debris being prevented from reentering the eye. In one embodiment, the flow restrictor includes barbs which hold it to the device after it has been severed, thereby preventing the flow restrictor from floating freely within the eye after it has been cut.

摘要翻译： 用于减轻眼压的技术和装置，其可能由逆行流回到眼睛中引起的炎症风险降低。 植入单向引流装置，其允许流体以最小压力梯度（5mmHg或更小）从眼睛流出，并且包括防止逆行流动的装置。 当植入时，排水通道最初由限流器限制。 在发生纤维化以防止可能导致低血压的过度引流之后，限流器被切断以允许流体自由流动离开眼睛，防止炎症碎屑重新进入眼睛。 在一个实施例中，流量限制器包括在切断装置之后将其保持在装置上的倒钩，从而防止流量限制器在切割之后在眼睛内自由浮动。

公开(公告)号：US5686095A

公开(公告)日：1997-11-11

申请号：US546740

申请日：1995-10-23

申请人： Francis W. Price, Jr.

发明人： Francis W. Price, Jr.

IPC分类号： A61K31/496 ,  A61K31/435 ,  A61K31/495

CPC分类号： A61K31/496 ,  Y10S514/928

摘要： A method of treating canker sores is disclosed by which a fluoroquinolone is topically applied to the ulcerous area. The fluoroquinolone is shown to be applied in solution form, and also as a paste, ointment, or gel. The fluoroquinolone is preferably applied three to eight times a day until the lesion disappears.

摘要翻译： 公开了一种治疗溃疡疮的方法，通过该方法将氟喹诺酮局部应用于溃疡区。 氟喹诺酮显示以溶液形式施用，也可以作为糊剂，软膏剂或凝胶剂使用。 氟喹诺酮优选每天施用三到八次，直到病变消失。