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公开(公告)号：US20110104228A1
公开(公告)日：2011-05-05
申请号：US12738397
申请日：2008-10-17
IPC分类号： A61F2/00 , A61K38/00 , A61K31/70 , A61K31/4353 , A61K39/395 , A61K31/7052 , A61P9/00 , A61L33/06 , A61K9/32
CPC分类号： A61L27/34 , A61L27/54 , A61L27/58 , A61L31/10 , A61L31/148 , A61L31/16 , A61L2300/416 , A61L2300/606
摘要： The invention features the use of a matrix consisting of low molecular weight components for use as a self-eliminating coating for implantable medical devices. The matrix coatings can be used to enhance biocompatibility and to control the local delivery of biologically active agents.
摘要翻译： 本发明的特征在于使用由低分子量组分组成的基质，用作可植入医疗装置的自消除涂层。 基质涂层可用于增强生物相容性并控制生物活性剂的局部递送。
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公开(公告)号：US08900603B2
公开(公告)日：2014-12-02
申请号：US13516913
申请日：2010-12-20
IPC分类号： A61K47/34 , A61K31/337 , A61K31/436 , A61L29/08 , A61L29/16 , A61L31/10 , A61L31/16 , C08G65/00 , C08L71/02
CPC分类号： A61L29/16 , A61K31/337 , A61K31/436 , A61K47/34 , A61K47/59 , A61K47/60 , A61K47/6957 , A61L29/085 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/606 , A61M25/10 , A61M2025/1045 , A61M2025/105 , C08G65/007 , C08L71/02 , C08L2203/02 , C08L27/12
摘要： The invention relates to oligofluorinated coatings and their use in drag delivery The oligofluorinated coatings are compositions comprising formula (XVII). These coatings are used in a method of delivering a biologically active agent to a tissue surface in a mammalian tissue This method occurs by contacting the surface with the coating including an oligofluorinated oligomer and a biologically active agent wherein the coating resides on the tissue surface and release the biologically active agent to the tissue surface.
摘要翻译： 本发明涉及寡氟化涂料及其在拖曳递送中的用途。低聚氟化涂料是包含式（XVII）的组合物。 这些涂层用于将生物活性剂递送到哺乳动物组织中的组织表面的方法。该方法通过使表面与包含低聚氟化低聚物和生物活性剂的涂层接触而发生，其中涂层驻留在组织表面上并释放 生物活性剂到组织表面。
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公开(公告)号：US20130142834A1
公开(公告)日：2013-06-06
申请号：US13516913
申请日：2010-12-20
IPC分类号： A61K47/34
CPC分类号： A61L29/16 , A61K31/337 , A61K31/436 , A61K47/34 , A61K47/59 , A61K47/60 , A61K47/6957 , A61L29/085 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/606 , A61M25/10 , A61M2025/1045 , A61M2025/105 , C08G65/007 , C08L71/02 , C08L2203/02 , C08L27/12
摘要： The invention relates to oligofluorinated coatings and their use in drag delivery The oligofluorinated coatings are compositions comprising formula (XVII). These coatings are used in a method of delivering a biologically active agent to a tissue surface in a mammalian tissue This method occurs by contacting the surface with the coating including an oligofluorinated oligomer and a biologically active agent wherein the coating resides on the tissue surface and release the biologically active agent to the tissue surface.
摘要翻译： 本发明涉及寡氟化涂料及其在拖曳递送中的用途。低聚氟化涂料是包含式（XVII）的组合物。 这些涂层用于将生物活性剂递送到哺乳动物组织中的组织表面的方法。该方法通过使表面与包含低聚氟化低聚物和生物活性剂的涂层接触而发生，其中涂层驻留在组织表面上并释放 生物活性剂到组织表面。
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