Substituted 5,6-dimethylpyrrolo[2,3-d]pyrimidine compounds, their
production and their medicinal use
    7.
    发明授权
    Substituted 5,6-dimethylpyrrolo[2,3-d]pyrimidine compounds, their production and their medicinal use 失效
    取代的5,6-二甲基吡咯并[2,3-d]嘧啶化合物,其生产及其药用

    公开(公告)号:US4229453A

    公开(公告)日:1980-10-21

    申请号:US28028

    申请日:1979-04-06

    CPC分类号: C07D487/04 C07D207/34

    摘要: The invention includes 5,6-dimethylpyrrolo [2,3-d]-pyrimidines (and method for their manufacture) of the formula ##STR1## or an acid-addition salt thereof, in which R is amino or hydroxy,R.sub.1 is halogen, nitro, C.sub.1 --C.sub.6 alkyl or alkoxy or CF.sub.3 and, where R is hydroxy, is also hydrogen,R.sub.2 is hydrogen, halogen or C.sub.1 --C.sub.6 -alkyl or alkoxy, andn is 1 or 2.Also included in the invention are pharmaceutical compositions containing said pyrrolo [2,3-d]-pyrimidines and the use of said compounds and compositions for treating CNS illnesses or inflammations.

    摘要翻译: 本发明包括式(I)的5,6-二甲基吡咯并[2,3-d] - 嘧啶(及其制备方法)或其酸加成盐,其中R为氨基或羟基,R1 是卤素,硝基,C 1 -C 6烷基或烷氧基或CF 3,并且其中R是羟基,也是氢,R 2是氢,卤素或C 1 -C 6烷基或烷氧基,n是1或2.也包括在本发明中 是含有所述吡咯并[2,3-d] - 嘧啶的药物组合物,以及所述化合物和组合物用于治疗CNS疾病或炎症的用途。

    Use of nitroethane derivatives as microbicides and specific nitroethane derivatives
    9.
    发明授权
    Use of nitroethane derivatives as microbicides and specific nitroethane derivatives 失效
    使用硝基乙烷衍生物作为杀菌剂和特定的硝基乙烷衍生物

    公开(公告)号:US06268514B1

    公开(公告)日:2001-07-31

    申请号:US09581420

    申请日:2000-06-13

    IPC分类号: C07D49302

    CPC分类号: C07D493/04 A01N43/90

    摘要: The use of nitroethane derivatives of the formula I where: R1 is hydrogen, unsubstituted or substituted C1-C6-alkyl, C3-C6-alkenyl, C3-C6-alkynyl, halogen, cyano or thiocyanato; R2 is hydrogen, formyl; halogen- or C1-C3-alkoxy-substituted or unsubstituted C1-C6-alkylcarbonyl, C2-C6-alkenylcarbonyl, C4-C6-alkyldienylcarbonyl or C2-C6-alkynylcarbonyl; A is unsubstituted or substituted phenyl, naphthyl, quinolyl, quinazolyl, quinoxalyl, 1-methylindolyl, 1-methylbenzimidazolyl, 2-methylindazolyl, benzofuranyl, benzothienyl, benzoxazolyl, benzothiazolyl, furyl, thienyl, pyrrolyl, isoxazolyl, isothiazolyl, pyrazolyl, oxazolyl, thiazolyl, imidazolyl, oxadiazolyl, thiadiazolyl, triazolyl, pyridinyl, pyridazinyl, pyrimidinyl, pyrazinyl or triazinyl, pyranyl or thiopyranyl; as microbicides is described.

    摘要翻译: 使用式I的硝基乙烷衍生物其中:R 1是氢,未取代或取代的C 1 -C 6 - 烷基,C 3 -C 6 - 烯基,C 3 -C 6 - 炔基,卤素,氰基或硫氰酸酯; R 2是氢,甲酰基; 卤素或C 1 -C 3烷氧基取代或未取代的C 1 -C 6烷基羰基,C 2 -C 6 - 烯基羰基,C 4 -C 6烷基二烯基羰基或C 2 -C 6 - 炔基羰基; A是未取代或取代的苯基,萘基,喹啉基,喹唑啉基,喹喔啉基 ,1-甲基吲哚基,1-甲基苯并咪唑基,2-甲基吲唑基,苯并呋喃基,苯并噻吩基,苯并恶唑基,苯并噻唑基,呋喃基,噻吩基,吡咯基,异恶唑基,异噻唑基,吡唑基,恶唑基,噻唑基,咪唑基,恶二唑基,噻二唑基,三唑基,吡啶基,哒嗪基,嘧啶基 ,吡嗪基或三嗪基,吡喃基或噻喃基;描述为杀微生物剂。