公开(公告)号：US20130203176A1

公开(公告)日：2013-08-08

申请号：US13701918

申请日：2011-06-03

申请人： Ryouta Maeba ,  Hiroshi Hara ,  Megumi Nishimukai ,  Yuya Yamazaki ,  Toru Nezu

发明人： Ryouta Maeba ,  Hiroshi Hara ,  Megumi Nishimukai ,  Yuya Yamazaki ,  Toru Nezu

IPC分类号： G01N33/92

CPC分类号： G01N33/92 ,  G01N33/48 ,  G01N2800/042 ,  G01N2800/044 ,  G01N2800/321 ,  G01N2800/323

摘要： The object of the present invention is to provide a biomarker which is highly correlated to the conventional biomarkers of metabolic syndrome or life-style related disease in a wide range of subjects to be tested, including subjects of special health check-up aged between 40 and 74, or an advantageous method for detecting metabolic syndrome or life-style related disease. The object can be solved by a method for detecting metabolic syndrome or life-style related disease characterized by comprising the step of measuring the concentration of choline plasmalogen in a sample to be tested.

摘要翻译： 本发明的目的是提供一种生物标志物，它与传统的代谢综合征或生活方式相关疾病的生物标志物在广泛的待测试对象中高度相关，包括年龄在40岁至40岁之间的特殊健康检查对象 74，或用于检测代谢综合征或生活方式相关疾病的有利方法。 可以通过检测代谢综合征或生活方式相关疾病的方法来解决该问题，其特征在于包括测量待测试样品中胆碱脂质体浓度的步骤。

公开(公告)号：US09134330B2

公开(公告)日：2015-09-15

申请号：US13701918

申请日：2011-06-03

申请人： Ryouta Maeba ,  Hiroshi Hara ,  Megumi Nishimukai ,  Yuya Yamazaki ,  Toru Nezu

发明人： Ryouta Maeba ,  Hiroshi Hara ,  Megumi Nishimukai ,  Yuya Yamazaki ,  Toru Nezu

IPC分类号： G01N33/92 ,  G01N33/48

CPC分类号： G01N33/92 ,  G01N33/48 ,  G01N2800/042 ,  G01N2800/044 ,  G01N2800/321 ,  G01N2800/323

摘要： The object of the present invention is to provide a biomarker which is highly correlated to the conventional biomarkers of metabolic syndrome or life-style related disease in a wide range of subjects to be tested, including subjects of special health check-up aged between 40 and 74, or an advantageous method for detecting metabolic syndrome or life-style related disease. The object can be solved by a method for detecting metabolic syndrome or life-style related disease by measuring the concentration of choline plasmalogen in a sample to be tested.

摘要翻译： 本发明的目的是提供一种生物标志物，它与传统的代谢综合征或生活方式相关疾病的生物标志物在广泛的待测试对象中高度相关，包括年龄在40岁至40岁之间的特殊健康检查对象 74，或用于检测代谢综合征或生活方式相关疾病的有利方法。 可以通过测量待测试样品中胆碱脂质体浓度的方法来检测代谢综合征或生活方式相关疾病的方法。

公开(公告)号：US5089404A

公开(公告)日：1992-02-18

申请号：US261162

申请日：1988-10-21

申请人： Wataru Matsumoto ,  Eiji Nakai ,  Toru Nezu ,  Kazuaki Suzuki

发明人： Wataru Matsumoto ,  Eiji Nakai ,  Toru Nezu ,  Kazuaki Suzuki

IPC分类号： C11C3/10 ,  C12P7/64

CPC分类号： C12P7/6454 ,  Y10S435/822 ,  Y10S435/829 ,  Y10S435/921 ,  Y10S435/931 ,  Y10S435/939

摘要： A process for the transesterification of substrates comprising (a) fat and oil and (b) one or more compounds selected from the group consisting of fatty acid, fatty acid ester and other fat and oil with the use of a lipase, wherein said transesterification is effected in the presence of a monohydric lower alcohol.

公开(公告)号：US4956287A

公开(公告)日：1990-09-11

申请号：US132213

申请日：1987-12-14

申请人： Kazuaki Suzuki ,  Shoji Maruzeni ,  Eiji Nakai ,  Toru Nezu

发明人： Kazuaki Suzuki ,  Shoji Maruzeni ,  Eiji Nakai ,  Toru Nezu

IPC分类号： A23D9/00 ,  C12P7/64

CPC分类号： C12P7/6472

摘要： The process for producing an oleaginous composition of the present invention comprises transesterifying a fat containing a large amount of polybasic unsaturated fatty acid(s) as constituting fatty acid(s) with saturated fatty acid(s) and/or saturated fatty acid alcohol ester(s) with the use of a lipase having an site-specificity to thereby give symmetric triglyceride(s) wherein the fatty acid groups at the 1- and 3-positions are selectively transesterified and a polybasic unsaturated fatty acid group is present at the 2-position. The above transesterification should be carried out under such conditions as to give an oleaginous composition which comprises 40% or more of symmetric triglyceride(s) each having a polybasic unsaturated fatty acid group at the 2-position and 50% or more of completely saturated fatty acid(s) each having 16 or more carbon atoms.