公开(公告)号：US20180245111A1

公开(公告)日：2018-08-30

申请号：US15755877

申请日：2016-03-25

申请人： Jinan University

发明人： Yong Wang ,  Manman Liu ,  Yinglai Teng ,  Aijun Li ,  Ning Zhang

IPC分类号： C12P7/64 ,  C12N9/20 ,  B01J8/02

CPC分类号： C12P7/6454 ,  B01J8/025 ,  B01J8/0292 ,  C12N9/20 ,  C12Y301/01003

摘要： Disclosed is a method for preparing a medium-long-chain triglyceride using a packed bed reactor, and belongs to the technical field of deep processing and modification of lipids. In the present invention, a medium-chain fatty acid triglyceride and a lipid as raw materials are subjected to a catalyzed transesterification using an immobilized enzyme having a 1,3 position-specificity being capable of catalyzing a transesterification reaction in the packed bed reactor to prepare a medium-long-chain triglyceride; the transesterification product is then subjected to an ethanol extraction to obtain a highly pure medium-long-chain triglyceride product; and the product remaining after the extraction useful as a raw material is backfilled into the reactor and continues to participate in the next batch of preparation of a medium-long-chain triglyceride.

公开(公告)号：US20180140650A1

公开(公告)日：2018-05-24

申请号：US15875098

申请日：2018-01-19

申请人： HELIAE DEVELOPMENT LLC

发明人： Sandip SHINDE ,  Stephen VENTRE ,  Jennifer LLOYD-RANDOLFI ,  Michael LAMONT

IPC分类号： A61K36/02 ,  C11C3/00 ,  A61K8/37 ,  A61K31/231 ,  A61Q19/00 ,  C12P7/64

CPC分类号： A61K36/02 ,  A61K8/37 ,  A61K31/231 ,  A61Q19/00 ,  C11C3/003 ,  C12P7/6454

摘要： Methods of producing high purity palmitoleic acid esters from natural oils are disclosed. The natural oils may comprise plant oil, nut oil, microalgae oil, and fish oil. The methods of processing the natural oil comprise transesterification with ethanol as the reacting solvent to produce ethyl esters. Methods of producing a high purity fraction of Omega-3, 6, & 9 fatty acid esters from natural oils are also disclosed. The high purity fatty acid esters may be used in nutrition, cosmetic, and nutraceutical products.

公开(公告)号：US20180139998A1

公开(公告)日：2018-05-24

申请号：US15571661

申请日：2016-05-04

申请人： ENZYMOTEC LTD.

发明人： Fabiana BAR-YOSEPH ,  Yael LIFSHITZ

IPC分类号： A23L33/115 ,  A23L33/00 ,  A23D9/04 ,  A61K31/202 ,  A61K31/201 ,  C11C3/08 ,  C12P7/64

CPC分类号： A23L33/115 ,  A23D9/04 ,  A23L33/40 ,  A61K31/201 ,  A61K31/202 ,  A61K31/23 ,  A61K31/231 ,  A61K31/232 ,  A61K45/06 ,  C11C3/08 ,  C12P7/6454 ,  C12P7/6472 ,  A61K2300/00

摘要： The present invention refers to a method for ore or both of improving sleep in a subject and treating at least one sleep problem in a subject. The method comprises administering to the subject an edible lipid composition which comprises a vegetable-derived fat source, wherein the fat source is a triglyceride fat source comprising triglycerides with 15-55% palmitic acid moieties out of the total fatty acids, and wherein the level of palmitic acid moieties at the sn-2 position of the glycerol backbone is at least 30% of total palmitic acid.

公开(公告)号：US09328315B2

公开(公告)日：2016-05-03

申请号：US14426706

申请日：2012-09-07

申请人： Rasmus Leth Miller ,  Mogens Bach

发明人： Rasmus Leth Miller ,  Mogens Bach

IPC分类号： A23D9/00 ,  C11B3/12 ,  C11B7/00 ,  C11C1/00 ,  C11C1/10 ,  C12P7/64

CPC分类号： C11B3/12 ,  C11B7/00 ,  C11B7/0016 ,  C11C1/005 ,  C11C1/10 ,  C12P7/6454

摘要： The invention relates to a process for separation of a processed vegetable fat (PVF), wherein said process comprises the steps of: in a distillation step (DIS), distilling the processed vegetable fat (PVF) into a distillate part (DPT) comprising stearic and oleic acid and/or esters thereof, and a distilled vegetable fat (DVF); in a first fractionation step (DFR), fractionating the distilled vegetable fat (DVF) into a first higher melting point fraction (FHF) being rich in tri-stearate triglycerides (StStSt, where St=stearic acid) and di-stearate diglycerides (StSt) and a first lower melting point fraction (FLF); and in a second fractionation step, fractionating the first lower melting point fraction (FLF) into a second higher melting point fraction (SHF) being rich in 1,3-distearyl-2-oleyl-triglycerides (StOSt, where O=oleic acid), and a second lower melting point fraction (SLF) being rich in 1-stearyl-2,3-dioleyl-triglycerides (StOO) and trioleate-triglycerides (OOO) in a solvent fractionation process (SFR). The invention furthermore relates to a vegetable fat product obtained from such process.

摘要翻译： 本发明涉及一种分离加工植物脂肪（PVF）的方法，其中所述方法包括以下步骤：在蒸馏步骤（DIS）中，将经加工的植物脂肪（PVF）蒸馏成包含硬脂酸酯的馏出物（DPT） 和油酸和/或其酯，以及蒸馏的植物脂肪（DVF）; 在第一分馏步骤（DFR）中，将蒸馏的植物脂肪（DVF）分馏成富含三硬脂酸甘油三酯（StStSt，其中St =硬脂酸）和二硬脂酸甘油二酯（StSt）的第一较高熔点馏分（FHF） ）和第一较低熔点分数（FLF）; 并且在第二分馏步骤中，将第一较低熔点馏分（FLF）分馏成富含1,3-二硬脂基-2-油基 - 甘油三酸酯（StOSt，其中O =油酸）的第二较高熔点馏分（SHF） ，以及在溶剂分馏过程（SFR）中富含1-硬脂基-2,3-二油基 - 甘油三酸酯（StOO）和三油酸甘油三酯（OOO）的第二较低熔点馏分（SLF）。 本发明还涉及从该方法获得的植物脂肪产品。

公开(公告)号：US08986941B2

公开(公告)日：2015-03-24

申请号：US13319403

申请日：2010-05-10

申请人： Thomas Louis François Favre ,  Henry Kos ,  Krishnadath Bhaggan ,  Sylvain Jacques Fages

发明人： Thomas Louis François Favre ,  Henry Kos ,  Krishnadath Bhaggan ,  Sylvain Jacques Fages

IPC分类号： C12N9/20 ,  C12Q1/61 ,  C12P7/64 ,  A23G1/38 ,  C11C3/08 ,  A61K38/00

CPC分类号： C12P7/6454 ,  A23G1/38 ,  C11C3/08

摘要： A process for preparing a triglyceride composition comprising from 50 to 80% by weight StOSt and from 5 to 20% by weight StOO comprises reacting triolein with stearic acid in the presence of a 1,3-specific lipase from Rhizopus oryzae to form interesterified glycerides and fractionating the interesterified triglycerides.

摘要翻译： 制备包含50-80％（重量）StOSt和5-20％（重量）StOO的甘油三酸酯组合物的方法包括在来自米曲霉的1,3-特异性脂肪酶存在下使三油酸酯与硬脂酸反应形成酯交换的甘油酯， 分离出酯交换的甘油三酸酯。

公开(公告)号：US08975055B2

公开(公告)日：2015-03-10

申请号：US13794173

申请日：2013-03-11

申请人： Frito-Lay Trading Company GmbH

发明人： Uwe Bornscheuer ,  Henrike Brundiek ,  Andrew Evitt ,  Stefan SaB ,  Friedericke Bonisch ,  Robert Kourist

IPC分类号： C12N9/20 ,  A23D9/04 ,  C12P7/64

CPC分类号： C12N9/20 ,  A23D9/04 ,  C12P7/6454

摘要： The present invention relates to a newly identified lipase belonging to the Ustilaginaceae family of Basidomycetes and variants thereof. The invention also relates to polynucleotides encoding the lipase and the variants thereof. The invention further relates to procedures for producing the lipase, and variants thereof, polypeptides and polynucleotides. The invention further relates to lipase variants with an increased trans-selectivity. The invention further relates to lipase variants with a preference for long chain fatty acid esters or carboxylic acid moieties with a chain length greater than C12. The invention further relates to a method of reducing, or eliminating, trans-fatty acids from liquid oil stable enough for frying systems.

摘要翻译： 本发明涉及属于Basidomycetes的Ustilaginaceae科的新鉴定的脂肪酶及其变体。 本发明还涉及编码脂肪酶的多核苷酸及其变体。 本发明还涉及产生脂肪酶的方法及其变体，多肽和多核苷酸。 本发明还涉及具有增加的反式选择性的脂肪酶变体。 本发明还涉及优选长链脂肪酸酯或链长大于C12的羧酸部分的脂肪酶变体。 本发明还涉及一种减少或消除来自液体油的反式脂肪酸足以用于煎炸系统的方法。

公开(公告)号：US20140193866A1

公开(公告)日：2014-07-10

申请号：US13902739

申请日：2013-05-24

申请人： DSM IP Assets B.V.

发明人： David Lam ,  David Weiner ,  Tim S. Hitchman ,  Nelson R. Barton ,  Jonathan D. Lyon

IPC分类号： C12P7/64

CPC分类号： C12P7/6418 ,  C12P7/6427 ,  C12P7/6445 ,  C12P7/6454 ,  C12P7/6472 ,  C12P7/6481 ,  C12P7/649 ,  Y02E50/13

摘要： The invention provides novel methods for making or modifying oils, e.g., plant animal or microbial oils, such as vegetable oils or related compounds, that are low in a particular fatty acid(s), for example, low linoleic oils, linolenic oils, low palmitic oils, low stearic oils or oils low in a combination thereof.

摘要翻译： 本发明提供用于制备或改性油的新方法，例如植物动物或微生物油，例如植物油或相关化合物，其在特定脂肪酸中是低的，例如低亚麻油，亚麻酸油，低 棕榈油，低硬脂油或低组合的油。

公开(公告)号：US08703442B2

公开(公告)日：2014-04-22

申请号：US12902241

申请日：2010-10-12

申请人： Esther Hendrika Gerarda Peeters ,  Marcus Bernardus Kruidenberg ,  Andrew James Dell

发明人： Esther Hendrika Gerarda Peeters ,  Marcus Bernardus Kruidenberg ,  Andrew James Dell

IPC分类号： C12P1/00 ,  C12P7/64 ,  C12N11/00 ,  C12N11/14 ,  C12N11/02

CPC分类号： C12P7/6481 ,  C12P7/6436 ,  C12P7/6454

摘要： A process for the modification of a substrate comprising passing the substrate through a packed bed column of a specific volume of immobilized enzyme wherein the substrate enters the column at or near one end of the column (the ‘inlet end’) and the modified substrate exits at or near the opposite end of the column (the ‘outlet end’), a portion of the volume of immobilized enzyme is periodically removed at or near to the inlet end of the column, and an equivalent portion of immobilized enzyme is periodically added at or near to the outlet end of the column.

摘要翻译： 一种用于修饰底物的方法，包括使基底通过特定体积的固定化酶的填充床柱，其中基底在塔的一端或其一端进入塔（“入口端”）并且改性基底离开 在柱的相对端（“出口端”）处或其附近，固定化酶体积的一部分在塔的入口端处或其附近被周期性地去除，并且固定化酶的等同部分周期性地添加在 或靠近柱的出口端。

公开(公告)号：US20140004581A1

公开(公告)日：2014-01-02

申请号：US14014927

申请日：2013-08-30

申请人： TRANSBIODIESEL LTD.

发明人： Sobhi BASHEER

IPC分类号： C12P7/64 ,  C12N9/20 ,  C12N9/96

CPC分类号： C12P7/649 ,  C10G2300/1014 ,  C10G2300/1018 ,  C11C3/04 ,  C12N9/20 ,  C12N9/96 ,  C12N11/00 ,  C12N11/02 ,  C12N11/14 ,  C12P7/6454 ,  Y02E50/13 ,  Y02P30/20

摘要： Disclosed is a process for the preparation of an interfacial enzyme immobilized on an insoluble support, by providing a bi-phase system comprised of an aqueous buffer solution and at least one first organic solvent; mixing said interfacial enzyme with the bi-phase system provided; adding the support to the obtained mixture and mixing; and isolating from the mixture obtained in the last step the interfacial enzyme immobilized on said support. The produced enzyme is locked in its catalytically active confirmation, and thus exhibits improved activity and stability. Also disclosed are uses of the produced enzymes, particularly in the preparation of biodiesel.

摘要翻译： 公开了通过提供由缓冲溶液和至少一种第一有机溶剂组成的双相体系制备固定在不溶性载体上的界面酶的方法; 将所述界面酶与所提供的双相系统混合; 向所得混合物中加入载体并混合; 并从最后步骤获得的混合物中分离固定在所述载体上的界面酶。 所产生的酶被锁定在其催化活性确认中，因此表现出改善的活性和稳定性。 还公开了所生产的酶的用途，特别是在生物柴油的制备中。

公开(公告)号：US20130210094A1

公开(公告)日：2013-08-15

申请号：US13808766

申请日：2011-07-25

申请人： Renal Backov ,  Clement Sanchez ,  Nicolas Brun ,  Herve Deleuze

发明人： Renal Backov ,  Clement Sanchez ,  Nicolas Brun ,  Herve Deleuze

IPC分类号： C12N11/14 ,  C12P7/62 ,  C12P7/64

CPC分类号： C12N11/14 ,  C12N9/20 ,  C12P7/62 ,  C12P7/6418 ,  C12P7/6454 ,  C12P7/649 ,  Y02E50/13 ,  Y02P20/588

摘要： The present invention relates to a heterogeneous enzymatic catalyst consisting of a macroprous silica monolith incorporating an enzyme immobilized by means of a compiling agent, to a process for preparing this enzymatic catalyst, to the use of the catalyst for carrying out chemical reactions by continuous flow heterogeneous enzymatic catalyst and to a process of continuous flow heterogeneous enzymatic catalysis using said catalyst.

摘要翻译： 本发明涉及由包含通过编译剂固定的酶的大型二氧化硅整流体与制备该酶催化剂的方法组成的多相催化剂，使用该催化剂进行连续流异构化的化学反应 酶催化剂和使用所述催化剂的连续流动异构酶催化过程。