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公开(公告)号：US5277182A
公开(公告)日：1994-01-11
申请号：US723692
申请日：1991-06-24
申请人： Hideaki Koizumi , Ryuzaburo Takeda , Hideki Kohno , Tetsuo Yokoyama , Yoshiyuki Miyamoto , Koichi Sano
发明人： Hideaki Koizumi , Ryuzaburo Takeda , Hideki Kohno , Tetsuo Yokoyama , Yoshiyuki Miyamoto , Koichi Sano
IPC分类号： A61B5/055 , G01R33/563
CPC分类号： A61B5/055 , G01R33/563
摘要： A method for imaging the coronary artery of a living body using nuclear magnetic resonance, wherein a patient is located in a static magneic field and the heart cycle of the patient is detected with the heart dilation period of the patient being determined in accordance with the detected heart cycle. Then, the coronary artery of the patient is portrayed on the nuclear magnetic resonance signal generated by applying high-frequency energy to the patient during the determined heart dilation period.
摘要翻译： 一种使用核磁共振对活体的冠状动脉成像的方法，其中患者位于静态磁场中，并且根据检测到的患者的心脏扩张周期被确定，患者的心脏周期被检测到 心脏周期。 然后，在确定的心脏扩张期间，将患者的冠状动脉描绘在通过对患者施加高频能量而产生的核磁共振信号上。
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公开(公告)号：US4889127A
公开(公告)日：1989-12-26
申请号：US37855
申请日：1987-04-13
IPC分类号： A61B10/00 , A61B5/055 , G01R33/48 , G01R33/563
CPC分类号： G01R33/563
摘要： A nuclear magnetic resonance imaging apparatus for deriving a signal from a moving part of an object to be imaged, includes a gradient magnetic field generator for applying a gradient magnetic field to the object; and a radio frequency magnetic field generator for applying a radio frequency magnetic field to the object to present a nuclear magnetic resonance phenomenon. Pulses of a 180 degree pulse method are generated to remove an adverse effect of ununiformity of a static magnetic field; two gradient magnetic fields having the same amplitude and grading oppositely to each other are applied at a certain time interval therebetween to the moving part of the object in the direction of motion of the moving object; a radio frequency magnetic field is generated by applying a pulse in the pulses of the 180 degree pulse method succeeding a 180 degree pulse at the time corresponding to the center of an echo signal generated by the 180 degree pulse, the radio frequency magnetic field making a nuclear spin vector at the stationary part of the object in parallel to the static magnetic field; a resonance signal is detected which is produced from the object upon application of the radio frequency magnetic field; the above process is performed to further obtain another resonance signal, reversing the polarities of the gradient magnetic fields; and a difference between the two resonance signals is derived as a signal from the moving part of the object.
摘要翻译： 用于从待成像对象的移动部分导出信号的核磁共振成像装置包括用于向对象施加梯度磁场的梯度磁场发生器; 以及用于对物体施加射频磁场以呈现核磁共振现象的射频磁场发生器。 产生180度脉冲方式的脉冲以消除静磁场不均匀性的不利影响; 以相对于彼此相反的幅度和等级的两个梯度磁场在其间的特定时间间隔被施加到物体的运动部分在运动物体的运动方向上; 通过在对应于由180度脉冲产生的回波信号的中心的时间的180度脉冲之后的180度脉冲方式的脉冲中施加脉冲，产生射频磁场来产生射频磁场， 核自旋矢量在物体的静止部分平行于静磁场; 检测在应用射频磁场时从物体产生的共振信号; 执行上述处理以进一步获得另一谐振信号，反转梯度磁场的极性; 并且导出两个谐振信号之间的差异作为来自物体的运动部分的信号。
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公开(公告)号：US5207222A
公开(公告)日：1993-05-04
申请号：US713316
申请日：1991-06-11
CPC分类号： G01R33/4804
摘要： Based on the relation that the higher the temperature of a portion to be measured, the lower becomes coherence of a nuclear spin at that portion, the present invention measures indirectly the temperature state of the portion to be measured from the change of intensity of NMR signals by utilizing this relationship. A transverse relaxation time is contained as one of the parameters in the relation between the signal intensity and the temperature; hence this transverse relaxation time is determined in advance for the portion to be measured and utilized in for the equation representing their relationship. This application discloses also an invention for determining a blood perfusion rate of the portion to be measured from the temperature data obtained in the manner described above.
摘要翻译： 基于测量部分的温度越高，该部分的核自旋的相关性越低，本发明根据NMR信号的强度的变化间接地测量待测部分的温度状态 通过利用这种关系。 横向弛豫时间作为信号强度与温度之间关系的参数之一; 因此该横向弛豫时间预先被测量的部分用于表示它们的关系的方程式。 本申请还公开了根据以上述方式获得的温度数据来确定待测量部分的血液灌注速率的发明。
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4.发明授权
公开(公告)号：US4902972A
公开(公告)日：1990-02-20
申请号：US254652
申请日：1988-10-24
CPC分类号： G01R33/4833 , G01R33/56
摘要： A method of and apparatus for generating nuclear magnetic resonance of an object. It is desirable that a nuclear magnetic resonance image be obtained in such a maner that a portion of the image in which the user is interested in is displayed in a greater scale. To this end, nuclear magnetic resonance signals from a specific region of the image are picke-up by an aliasing phenomenon, into a predetermined signal band which is different from the signal band of the above-mentioned specific region.
摘要翻译： PCT No.PCT / JP87 / 01021 Sec。 371日期：1988年10月24日第 102（e）日期1988年10月24日PCT 1987年12月23日PCT。一种用于产生物体的核磁共振的方法和装置。 期望以更大的尺度显示用户感兴趣的图像的一部分的方式获得核磁共振图像。 为此，来自图像的特定区域的核磁共振信号通过混叠现象被拾取到与上述特定区域的信号频带不同的预定信号频带。
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公开(公告)号：USRE34495E
公开(公告)日：1994-01-04
申请号：US725514
申请日：1991-07-03
申请人： Koichi Sano , Tetsuo Yokoyama , Ryuzaburo Takeda , Yasuhiko Ozawa , Shinichi Sato , Hideaki Koizumi
发明人： Koichi Sano , Tetsuo Yokoyama , Ryuzaburo Takeda , Yasuhiko Ozawa , Shinichi Sato , Hideaki Koizumi
IPC分类号： G01F1/716 , G01P5/00 , G01R33/563 , A61B5/055
CPC分类号： G01F1/716 , G01P5/00 , G01R33/56308 , G01R33/56316
摘要： A slice selection gradient magnetic field used in a pulse sequence for generating a spin echo signal is applied in such a fashion that its polarity at the time of a 90.degree. pulse becomes opposite to the one at the time of 180.degree. pulse, in order to expand a dynamic range of blood flow speed measurement. When the blood flow speed contains a component in a slice vertical direction, the gradient magnetic field in the slice vertical direction is adjusted so that the phase changes of two sets of flow encoded pulses contained in the slice vertical direction are opposite to each other.The flow speed in the direction of the readout gradient magnetic field, which is a lateral direction of the slice plane, is purely measured by canceling influences of the flow in the slice vertical direction.
摘要翻译： 施加用于产生自旋回波信号的脉冲序列中的切片选择梯度磁场，使得其在90度脉冲时的极性与180度脉冲时的极性相反，以便 扩大血流速度测量的动态范围。 当血流速度包含切片垂直方向上的分量时，调整切片垂直方向上的梯度磁场，使得包含在切片垂直方向上的两组流动编码脉冲的相位变化彼此相反。 通过消除切片垂直方向上的流动的影响，纯粹地测量作为切片平面的横向的读出梯度磁场的方向上的流速。
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公开(公告)号：US5016637A
公开(公告)日：1991-05-21
申请号：US356418
申请日：1989-05-25
IPC分类号： A61B10/00 , A61B5/055 , G01R33/48 , G01R33/563 , G01R33/567
CPC分类号： G01R33/5673 , G01R33/563
摘要： An MRI method is disclosed, by which, when liquid moving in a body to be examined stays in a predetermined region, this region is excited by using the nuclear magnetic resonance phenomenon and when the liquid thus excited moves from that excited region, a nuclear magnetic resonance signal produced by the excited spin and emitted during the relaxation time thereof is detected.
摘要翻译： 公开了一种MRI方法，通过该方法，当待检查的体内移动的液体停留在预定区域时，通过使用核磁共振现象来激发该区域，并且当该激发的液体从该激发区域移动时， 检测在其弛豫时间期间由激发的自旋产生并发射的共振信号。
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公开(公告)号：US4844077A
公开(公告)日：1989-07-04
申请号：US170695
申请日：1988-03-14
申请人： Koichi Sano , Tetsuo Yokoyama , Ryuzaburo Takeda , Yasuhiko Ozawa , Shinichi Sato , Hideaki Koizumi
发明人： Koichi Sano , Tetsuo Yokoyama , Ryuzaburo Takeda , Yasuhiko Ozawa , Shinichi Sato , Hideaki Koizumi
IPC分类号： G01F1/716 , G01R33/563
CPC分类号： G01F1/716 , G01R33/56308 , G01R33/56316
摘要： A slice selection gradient magnetic field used in a pulse sequence for generating a spin echo signal is applied in such a fashion that its polarity at the time of a 90.degree. pulse becomes opposite to the one at the time of 180 .degree. pulse, in order to expand a dynamic range of blood flow speed measurement. When the blood flow speed contains a component in a slice vertical direction, the gradient magnetic field in the slice vertical direction is adjusted so that the phase changes of two sets of flow encoded pulses contained in the slice vertical direction are opposite to each other.The flow speed in the direction of the readout gradient magnetic field, which is a lateral direction of the slice plane, is purely measured by cancelling influences of the flow in the slice vertical direction.
摘要翻译： 施加用于产生自旋回波信号的脉冲序列中的切片选择梯度磁场，使得其在90度脉冲时的极性与180度脉冲时的极性相反，以便 扩大血流速度测量的动态范围。 当血流速度包含切片垂直方向上的分量时，调整切片垂直方向上的梯度磁场，使得包含在切片垂直方向上的两组流动编码脉冲的相位变化彼此相反。 通过消除切片垂直方向上的流动的影响，纯粹地测量作为切片平面的横向的读出梯度磁场的方向上的流速。
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公开(公告)号：US4814709A
公开(公告)日：1989-03-21
申请号：US59879
申请日：1987-05-26
CPC分类号： G01R33/4838 , G01R33/482
摘要： This invention relates to a selection method of a specific region of a sample which is suitable for use in a nuclear magnetic resonance (NMR) imaging. Selection of a specific region suitable for obtaining multi-dimensional spatial information can be preferably made. To satisfy this requirement, the spin of the specific region of the sample is brought down in a direction at right angles to a static magnetic field, the regions other than the specific region are, in the mean time, brought down in a direction at right angles to the static magnetic field, and thereafter the static magnetic field is rendered non-uniform to that the spins of the regions other than the specific region become saturated.
摘要翻译： PCT No.PCT / JP86 / 00492 Sec。 371日期：1987年5月26日 102（e）日期1987年5月26日PCT PCT日期为1986年9月25日。本发明涉及适用于核磁共振（NMR）成像的样品的特定区域的选择方法。 可以优选选择适于获得多维空间信息的特定区域。 为了满足这一要求，样品的特定区域的旋转沿与静磁场成直角的方向下降，特定区域以外的区域同时沿着向右的方向下降 与静磁场成角度，此后静电磁场变得不均匀，使特定区域以外的区域的自旋变得饱和。
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公开(公告)号：US4736160A
公开(公告)日：1988-04-05
申请号：US867541
申请日：1986-05-28
申请人： Koichi Sano , Shimbu Yamagata , Koichi Haruna , Hideaki Koizumi , Shinichi Sato , Tetsuo Yokoyama , Ryuzaburo Takeda
发明人： Koichi Sano , Shimbu Yamagata , Koichi Haruna , Hideaki Koizumi , Shinichi Sato , Tetsuo Yokoyama , Ryuzaburo Takeda
IPC分类号： G01R33/54 , G01R33/565 , G01R33/20
CPC分类号： G01R33/565 , G01R33/54 , G01R33/56563
摘要： In order to make an accurate display possible even in case image data having been subjected to a Fourier transformation have negative values, the sampling timing deviations of measured signals having phase errors based on various factors are detected from the gradient of the linear components of the image data having been subjected to the Fourier transformation, and the density values of the image having the detected timing deviations corrected are displayed.
摘要翻译： 为了即使在已经进行了傅立叶变换的图像数据的情况下，即使在具有负值的情况下也可以进行准确的显示，根据图像的线性分量的梯度来检测具有基于各种因素的相位误差的测量信号的采样定时偏差 已经进行傅里叶变换的数据，并且显示校正了检测到的定时偏差的图像的浓度值。
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公开(公告)号：US5165411A
公开(公告)日：1992-11-24
申请号：US672757
申请日：1991-03-22
IPC分类号： G01R33/54 , A61B5/055 , A61B10/00 , G01R33/32 , G01R33/567
CPC分类号： G01R33/5676
摘要： A radio frequency magnetic field is applied to a sample or object to be examined which is placed in a static magnetic field and oscillates periodically, and nuclear magnetic resonance signals are generated from the sample. The NMR signal is transformed to a signal having a form wherein a still image component and an artifact component resulting from the periodic oscillation, that are contained in the NMR signal, are mutually separated, and then processing is applied to the signal thus transformed so as to remove the artifact component therefrom. Inverse transform to the transform described above is applied to the signal thus processed.
摘要翻译： 将射频磁场施加到放置在静态磁场中并被周期性振荡的待检查的样品或物体，并且从样品产生核磁共振信号。 NMR信号被变换为具有形式的信号，其中包含在NMR信号中的由周期性振荡产生的静态图像分量和伪像分量相互分离，然后将处理应用于如此变换的信号，以便 从中删除工件组件。 将对上述变换的逆变换应用于由此处理的信号。
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