公开(公告)号：US20200024232A1

公开(公告)日：2020-01-23

申请号：US16415482

申请日：2019-05-17

Applicant: SABIC GLOBAL TECHNOLOGIES B.V.

Inventor： Deshmukh Sandesh Shivajirao ,  Shivakumar Konda ,  Sivakumar Sreeremagiri ,  Sivakumar Periyasamy ,  Ravi Gautam ,  Srinivasan Namala ,  Ganesan Balakrishnan

IPC: C07D209/46 ,  C08G64/12 ,  C08G64/30

Abstract: A method for the purification of a 2-aryl-3,3-bis(hydroxyaryl)phthalimidine of formula (I), the method comprising heating a reaction mixture comprising a phenolphthalein compound of formula (II) and a primary arylamine of formula (III) in the presence of an acid catalyst to form a reaction mixture; removing water from the reaction mixture; quenching the reaction mixture with an aqueous alkali solution to form a quenched reaction mixture; extracting the quenched reaction mixture with an aminoaryl compound of formula (IV) to form an organic layer and an extracted aqueous layer comprising a crude 2-aryl-3,3-bis(hydroxyaryl)phthalimidine compound; contacting the extracted aqueous layer with carbon to form a semi-purified 2-aryl-3,3-bis(hydroxyaryl)phthalimidine compound; and mixing the semi-purified 2-aryl-3,3-bis(hydroxyaryl)phthalimidine compound with a solution comprising an alcohol and an acid to form a purified 2-aryl-3,3-bis(hydroxyaryl)phthalimidine of formula (I); wherein formulas (I), (II), (III), and (IV) are as provided herein.

公开(公告)号：US10544096B2

公开(公告)日：2020-01-28

申请号：US16316539

申请日：2017-07-12

Applicant: SABIC GLOBAL TECHNOLOGIES B.V.

Inventor： Sivakumar Sreeramagiri ,  Deshmukh Sandesh Shivajirao ,  Samir Anapat ,  Vishal Keshaorao Karmore ,  Sanjay Katrekar ,  Alok Pal

IPC: C07D209/46 ,  C07D209/44 ,  C08G64/30 ,  C08G64/12

Abstract: A continuous method for the manufacture of a 2-aryl-3,3-bis(hydroxyaryl)phthalimidine comprising continuously heating an anhydride with a phenol in the presence of a catalyst and a first co-catalyst, to form a first reaction mixture comprising a phenolphthalein compound; precipitating the phenolphthalein compound; combining a primary arylamine with an acid catalyst and a second co-catalyst to form a second reaction mixture; adding the phenolphthalein compound to the second reaction mixture; continuously heating the second reaction mixture to provide a third reaction mixture comprising a crude phthalimidine; and treating the crude phthalimidine to remove aminophenol and purify the phthalimidine is provided.