公开(公告)号：US10918725B2

公开(公告)日：2021-02-16

申请号：US15762165

申请日：2016-09-30

Applicant: SAMJIN PHARMACEUTICAL CO., LTD.

Inventor： Eui-Hwan Cho ,  Sung-Ju Choi ,  Sung-Woo Lee ,  Hee-Jong Shin ,  Min-Hyo Ki ,  Mee-Hwa Choi ,  Dong-Ha Lee

IPC: A61K47/40 ,  A61K9/48 ,  A61K9/08 ,  A61K31/4704 ,  A61K47/02 ,  A61K47/10 ,  A61K47/18 ,  A61K47/22 ,  A61K47/32 ,  A61K47/34 ,  A61K47/38 ,  A61K9/00 ,  A61K47/44

Abstract: An ophthalmic composition is provided that includes rebamipide and a method for preparing the same. The ophthalmic composition of maintains its transparency for a long time even in a physiologically neutral to weakly basic pH range that does not injure the cornea and conjunctiva of a patient suffering from dry eye and has improved stability so as not to be re-dispersed.

公开(公告)号：US20190038564A1

公开(公告)日：2019-02-07

申请号：US16075399

申请日：2017-01-24

Applicant: SAMJIN PHARMACEUTICAL CO., LTD.

Inventor： Eui Hwan Cho ,  Sung-Ju Choi ,  Sung-Woo Lee ,  Hee-Jong Shin ,  Min-Hyo Ki ,  Mee-Hwa Choi ,  Tae-Hoon Oh

IPC: A61K9/28 ,  A61K9/20 ,  A61K9/00 ,  A61K31/403

Abstract: Disclosed is an immediate-release carvedilol formulation, which is configured such that a coating layer including a polymer, wax, fatty acid and/or fatty acid ester is formed on the surface thereof. This formulation has improved madescent, and thus can exhibit high stability, in which the initial appearance of the formulation can be maintained without cracking or breaking even under storage conditions at high relative humidity.