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公开(公告)号:US20130210655A1
公开(公告)日:2013-08-15
申请号:US13721913
申请日:2012-12-20
Applicant: SAMSUNG TECHWIN CO., LTD.
Inventor: Song Chun CHONG , John HARVEY
IPC: C12Q1/68
CPC classification number: C12Q1/683 , C12Q1/6823 , C12Q1/6825 , C12Q2521/327 , C12Q2525/121 , C12Q2565/1015 , C12Q2565/501
Abstract: Provided is an array including a plurality of target specific array nucleic acid molecules wherein each target specific array nucleic acid molecule contains: (i) a 5′-end DNA segment, (ii) a 3′-end DNA segment, and (iii) an RNA sequence of 1-6 bases within the molecule; and wherein each of the 5-end of the target specific array nucleic acid molecules is coupled to a detectable label. A method for detecting a target nucleic acid and a method for detecting polymorphism in a target nucleic using the array are also provided.
Abstract translation: 提供了包含多个靶特异性阵列核酸分子的阵列,其中每个靶特异性阵列核酸分子包含:(i)5'端DNA片段,(ii)3'末端DNA片段,和(iii) 分子内有1-6个碱基的RNA序列; 并且其中靶特异性阵列核酸分子的5末端中的每一个与可检测标记偶联。 还提供了使用该阵列检测靶核酸的方法和检测靶核酸中的多态性的方法。