公开(公告)号：US20190153078A1

公开(公告)日：2019-05-23

申请号：US16204624

申请日：2018-11-29

申请人： SANOFI PASTEUR BIOLOGICS, LLC

发明人： Stephen F. Anderson ,  Natalie Anosova ,  Nicola Beltraminelli ,  Pierre Garrone ,  Harold Kleanthous ,  Jianxin Zhang ,  Majid Mehtali

IPC分类号： C07K16/12 ,  A61K39/40

摘要： Monoclonal antibodies, or antigen-binding fragments thereof, that bind to Clostridium difficile (C. difficile) toxin A or toxin B and methods of using the same to detect or treat C. difficile infections and/or C. difficile-associated disease.

公开(公告)号：US10160797B2

公开(公告)日：2018-12-25

申请号：US14776146

申请日：2014-03-14

申请人： SANOFI PASTEUR BIOLOGICS, LLC ,  BLINK BIOMEDICAL SAS

发明人： Stephen F. Anderson ,  Natalie Anosova ,  Nicola Beltraminelli ,  Pierre Garrone ,  Harold Kleanthous ,  Jianxin Zhang ,  Majid Mehtali

IPC分类号： C07K16/00 ,  C07K16/12 ,  A61K39/40 ,  A61K39/00

摘要： Monoclonal antibodies or antigen-binding fragments thereof, that bind to Clostridium difficile (C. difficile ) toxin A or toxin B and methods of using the same to detect or treat C. difficile infections and/or C. difficile -associated disease. C. difficile is a gram positive, anaerobic bacterium that causes gastrointestinal disease in humans. The bacteria are transmitted through feces and spread to food and other surfaces when people who are infected do not thoroughly wash their hands.

公开(公告)号：US20220089700A1

公开(公告)日：2022-03-24

申请号：US17538731

申请日：2021-11-30

申请人： SANOFI PASTEUR BIOLOGICS, LLC

发明人： Stephen F. Anderson ,  Natalie Anosova ,  Nicola Beltraminelli ,  Pierre Garrone ,  Harold Kleanthous ,  Majid Mehtali ,  Jianxin Zhang

IPC分类号： C07K16/12 ,  A61K39/40

摘要： Monoclonal antibodies, or antigen-binding fragments thereof, that bind to Clostridium difficile (C. difficile) toxin A or toxin B and methods of using the same to detect or treat C. difficile infections and/or C. difficile-associated disease.

公开(公告)号：US11220537B2

公开(公告)日：2022-01-11

申请号：US16204624

申请日：2018-11-29

申请人： SANOFI PASTEUR BIOLOGICS, LLC

发明人： Stephen F. Anderson ,  Natalie Anosova ,  Nicola Beltraminelli ,  Pierre Garrone ,  Harold Kleanthous ,  Jianxin Zhang ,  Majid Mehtali

IPC分类号： C07K16/00 ,  C07K16/12 ,  A61K39/40 ,  A61K39/00

摘要： Monoclonal antibodies, or antigen-binding fragments thereof, that bind to Clostridium difficile (C. difficile) toxin A or toxin B and methods of using the same to detect or treat C. difficile infections and/or C. difficile-associated disease.