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    ANTIBODIES TO CYTOKINE RECEPTOR ZCYTOR19
    5.
    发明申请
    ANTIBODIES TO CYTOKINE RECEPTOR ZCYTOR19 审中-公开
    细胞因子受体ZCYTOR19的抗体

    公开(公告)号：US20070048846A1

    公开(公告)日：2007-03-01

    申请号：US11539079

    申请日：2006-10-05

    申请人： SCOTT PRESNELL ,  WENFENG XU ,  JULIA NOVAK ,  THEODORE WHITMORE ,  FRANCIS GRANT

    发明人： SCOTT PRESNELL ,  WENFENG XU ,  JULIA NOVAK ,  THEODORE WHITMORE ,  FRANCIS GRANT

    IPC分类号： C12P21/08 ,  C12P21/04 ,  C07K16/28

    CPC分类号： C07K14/47 ,  C07K14/715 ,  C07K2319/00 ,  Y10T436/143333

    摘要： Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor19, a novel class II cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor19, are located on chromosome 1p36.11, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

    摘要翻译： 公开了新型多肽，编码多肽的多核苷酸，以及相关的组合物和方法，用于zcytor19，一种新型的II类细胞因子受体。 多肽可用于检测在体外和体内刺激造血，淋巴和骨髓细胞增殖和/或发育的配体的方法。 配体结合受体多肽也可用于在体外和体内阻断配体活性。 编码zcytor19的多核苷酸位于染色体1p36.11上，可用于鉴定与人类疾病状态相关的基因组区域。 本发明还包括生产蛋白质的方法，用途及其抗体。

    CYTOKINE RECEPTOR ZCYTOR19
    6.
    发明申请
    CYTOKINE RECEPTOR ZCYTOR19 有权
    细胞因子受体ZCYTOR19

    公开(公告)号：US20070048799A1

    公开(公告)日：2007-03-01

    申请号：US11539072

    申请日：2006-10-05

    申请人： SCOTT PRESNELL ,  WENFENG XU ,  JULIA NOVAK ,  THEODORE WHITMORE ,  FRANCIS GRANT

    发明人： SCOTT PRESNELL ,  WENFENG XU ,  JULIA NOVAK ,  THEODORE WHITMORE ,  FRANCIS GRANT

    IPC分类号： G01N33/53 ,  C07H21/04 ,  C12P21/06 ,  C07K14/715

    CPC分类号： C07K14/47 ,  C07K14/715 ,  C07K2319/00 ,  Y10T436/143333

    摘要： Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor19, a novel class II cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor19, are located on chromosome 1p36.11, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

    摘要翻译： 公开了新型多肽，编码多肽的多核苷酸，以及相关的组合物和方法，用于zcytor19，一种新型的II类细胞因子受体。 多肽可用于检测在体外和体内刺激造血，淋巴和骨髓细胞增殖和/或发育的配体的方法。 配体结合受体多肽也可用于在体外和体内阻断配体活性。 编码zcytor19的多核苷酸位于染色体1p36.11上，可用于鉴定与人类疾病状态相关的基因组区域。 本发明还包括生产蛋白质的方法，用途及其抗体。