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1.发明公开公开(公告)号：US20240342071A1
公开(公告)日：2024-10-17
申请号：US18755705
申请日：2024-06-27
发明人： WENFENG DING , YAN PENG , XUE CHEN , WENHAO ZHAO , XINLIN SUN , CHUNQING HUANG , FUYI GUAN , YU XIAO
CPC分类号： A61K8/64 , A61Q19/00 , C07K7/06 , A61K2800/56
摘要： The present invention relates to a hexapeptide, a cosmetic composition or a pharmaceutical composition thereof, and a use thereof, the peptide has the following general formula: R1-Phe-Phe-Trp-Phe-X1-X2-R2. The peptide of the present invention, a stereoisomer thereof, or a mixture of stereoisomers thereof, or a cosmetically acceptable salt thereof, or a pharmaceutically acceptable salt thereof, or their cosmetic compositions or pharmaceutical compositions, and their uses in the preparation of a cosmetic composition or a pharmaceutical composition for anti-inflammation and skin barrier repair.
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2.发明公开公开(公告)号：US20240301000A1
公开(公告)日：2024-09-12
申请号：US18653953
申请日：2024-05-02
发明人： WENFENG DING , YAN PENG , XUE CHEN , WENHAO ZHAO , XINLIN SUN , CHUNQING HUANG , FUYI GUAN , YU XIAO
CPC分类号： C07K5/1024 , A61K8/64 , A61P29/00 , A61Q19/02 , A61K38/00
摘要： A peptide derivative and a cosmetic composition or pharmaceutical composition and use thereof. The peptide derivative has the following general formula: R1—Pro-Lys-Glu-Lys-R2. The peptide derivative is obtained by means of covalent binding of niacin, tranexamic acid or kojic acid with a peptide, has the effects of relieving skin inflammation reaction and inhibiting melanin generation, and can be used in the fields of cosmetics or medicines for anti-inflammation as well as whitening and freckle-removing of skin, especially for improving post-inflammation hyperpigmentation.
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3.发明公开公开(公告)号：US20240279275A1
公开(公告)日：2024-08-22
申请号：US18653960
申请日：2024-05-02
发明人： WENFENG DING , YAN PENG , XUE CHEN , WENHAO ZHAO , XINLIN SUN , CHUNQING HUANG , FUYI GUAN , YU XIAO
CPC分类号： C07K5/0806 , A61K8/64 , A61P39/06 , A61Q19/08 , A61K38/00
摘要： Provided are a peptide derivative and a cosmetic composition or pharmaceutical composition and use thereof. The peptide derivative has a general formula as follows: R1-Gly-Pro-Gln-Gly-Pro-Gln-R2. The peptide derivative is obtained by covalently binding caffeic acid and gallic acid to peptide, respectively; and compared with single caffeic acid, gallic acid and single polypeptide, the peptide derivative has excellent skin photoaging and anti-oxidation effects, and can be applied to the fields of cosmetics, medicines, and the like.
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