公开(公告)号：US20210139567A1

公开(公告)日：2021-05-13

申请号：US17096203

申请日：2020-11-12

Applicant: SHIMADZU CORPORATION ,  OSAKA INSTITUTE OF PUBLIC HEALTH

Inventor： Koichi KOJIMA ,  Kanae TERAMOTO ,  Shinichi IWAMOTO ,  Yuki WAKABAYASHI ,  Junko SAKATA

IPC: C07K16/12 ,  G01N33/68 ,  G01N30/72

Abstract: A method for detecting verotoxin includes: providing a sample and a molecule that binds to verotoxin; performing an operation for purifying verotoxin in the sample by using binding of the molecule and the verotoxin; and subjecting the sample obtained by the operation to a first mass spectrometry.

公开(公告)号：US20220277951A1

公开(公告)日：2022-09-01

申请号：US17638062

申请日：2020-06-04

Applicant: SHIMADZU CORPORATION

Inventor： Shinichi IWAMOTO ,  Sadanori SEKIYA

IPC: H01J49/42

Abstract: An ion trap mass spectrometer includes an ion trap including a first electrode and a second electrode different from the first electrode, a first voltage controller that periodically switches a DV voltage among DC voltages having a plurality of values and apply the DV voltages to the first electrode, and a second voltage controller that applies a sine-wave voltage to the second electrode when ions captured in the ion trap are dissociated.

公开(公告)号：US20190274664A1

公开(公告)日：2019-09-12

申请号：US16298091

申请日：2019-03-11

Applicant: Shimadzu Corporation

Inventor： Shinichi IWAMOTO

IPC: A61B10/02 ,  G01N33/68

Abstract: A test subject takes a component collection tool with his/her fingers, and rolls the tool between pads of the fingers several times to transfer components attached on a skin surface to a surface of the tool. The component collection tool is immersed in a predetermined solvent to allow the components on the skin surface to be dissolved in the solvent. Bligh-Dyer method may be used therefor, for example. From a liquid in which lipid or others are thus collected, a sample for analysis using MALDI-MS or LDI-MS is prepared and subjected to the analysis. Accordingly, components on the skin surface of the test subject can be efficiently collected and subjected to analysis with burden on the test subject being reduced.

公开(公告)号：US20190115198A1

公开(公告)日：2019-04-18

申请号：US16162503

申请日：2018-10-17

Applicant: SHIMADZU CORPORATION

Inventor： Shinichi IWAMOTO ,  Yusaku HIOKI

IPC: H01J49/04 ,  H01J49/16 ,  H01J49/00 ,  G06K7/14

Abstract: An imager 13 takes an image of a sample-placement surface of a sample plate 5. A plate identifier 103 decodes a barcode on the image to acquire a plate ID, recognizes the well arrangement, and retrieves a template having a cell arrangement corresponding to the well arrangement from a plate information storage section 101. A sample presence identifier 104 identifies, from the image, a well on which a sample is placed. A plate correspondence information input assistant 105 creates a template image in which the background color of the cells is changed depending on the presence of the sample, and displays it on a display unit 12. An analysis operator inputs information into each cell by a direct character-input operation or a drag-and-drop operation from a previously created sample list. The inputted information is associated with the corresponding well number and stored in a registration information storage section 107.

公开(公告)号：US20220068622A1

公开(公告)日：2022-03-03

申请号：US17399135

申请日：2021-08-11

Applicant: SHIMADZU CORPORATION

Inventor： Shinichi IWAMOTO ,  Kanae TERAMOTO

IPC: H01J49/00 ,  G16C20/20 ,  G01N33/68

Abstract: Provided is a display-processing device for mass spectrometry data capable of presenting a mass spectrum of a test microorganism and existing genome-related information so that the relationship between the two kinds of information can be easily understood. In the device, a spectrum acquirer (41) acquires a mass spectrum (80) of a test microorganism. A genome-related information acquirer (42) acquires genome-related information of a known microorganism which is identical or related to the test microorganism, based on the mass spectrum. A correspondence relationship determiner (43) determines a correspondence relationship between peaks on the mass spectrum and proteins expressed in the known microorganism. A display controller (45) displays, on a display device, identifiers (81) and a genome map (70) along with the mass spectrum, each identifier indicating what protein corresponds to a given peak, and the genome map showing the location of the gene encoding each protein on the genome.