公开(公告)号：US20190234916A1

公开(公告)日：2019-08-01

申请号：US16318181

申请日：2016-08-23

Applicant: SHIMADZU CORPORATION

Inventor： Yutaro YAMAMURA ,  Toshikazu MINOHATA

IPC: G01N30/72 ,  H01J49/00 ,  H01J49/04 ,  H01J49/02

Abstract: A mass spectrometry data processor (2) having a database (21) for storing respective pieces of mass spectrum data of various compounds together with names and mass spectrometry conditions of the compounds includes a mass spectrum data receiver (22) configured to receive input of mass spectrum data associated with a compound name and a mass spectrometry condition, a determination unit (25) configured to determine whether the mass spectrum data includes a mass peak satisfying a predetermined criterion, and a database registration unit (31) that registers, on the database, mass spectrum data determined to include the mass peak satisfying the predetermined criterion or mass spectrum data based on the mass spectrum data determined to include the mass peak satisfying the predetermined criterion together with a compound name and a mass spectrometry condition.

公开(公告)号：US20140244185A1

公开(公告)日：2014-08-28

申请号：US13781218

申请日：2013-02-28

Applicant: SHIMADZU CORPORATION

Inventor： Yutaro YAMAMURA ,  Tohru SHIOHAMA ,  Yuji KATSUYAMA

IPC: H01J49/00

Abstract: Sequential identification numbers are automatically provided and undisplayed, constant, unique numbers are assigned to each event registered in an analysis condition setting table 100. Since correspondence information between the identification numbers and the unique numbers changes due to the reassignment of identification numbers when an event is deleted from the table, event identification numbers for each compound are changed by referring to the correspondence information on a compound information table. As a result, it is possible to avoid the misalignment of event identification numbers between both tables. In addition, when an instruction is given to coordinate the time information or m/z information on both tables, the information on one table is reflected on the other table in accordance with the identification numbers.

Abstract translation: 顺序识别号被自动提供并且不显示，对分配条件设置表100中登记的每个事件分配恒定的唯一号码。由于当事件为事件时识别号码与唯一号码之间的对应信息由于识别号码的重新分配而改变 从表中删除，通过参照复合信息表的对应信息来改变每个化合物的事件识别号码。 结果，可以避免两个表之间的事件识别号码的错位。 此外，当给出两个表上的时间信息或m / z信息的协调指令时，根据识别号码在另一个表上反映一个表上的信息。

公开(公告)号：US20190011410A1

公开(公告)日：2019-01-10

申请号：US15762818

申请日：2015-09-25

Applicant: SHIMADZU CORPORATION

Inventor： Kengo MAEDA ,  Tomohiro KAWASE ,  Yutaro YAMAMURA ,  Tomoomi HOSHI

IPC: G01N30/86 ,  G01N27/62 ,  G06K9/00 ,  G01N27/70 ,  G01N30/72 ,  H01J49/00

Abstract: A degree of similarity in the peak pattern between a mass spectrum obtained for an unknown target substance in a sample and a mass spectrum of a known specific substance is calculated (S4). If the degree of similarity is within a range of 80-60% (“No” in S6), the ratio between the signal intensities at two mass-to-charge ratios characteristic of the specific substance is calculated and compared with a reference value (S7 and S8). If the intensity ratio exceeds the reference value, the target substance is likely to be the specific substance. Therefore, as in the case where the degree of similarity is equal to or higher than 80%, it is concluded that the specific substance is contained in the sample (S10). In advance of such a judgment, whether or not the sample has been certainly subjected to the mass spectrometric analysis is determined from a graph of the total ion current signal created from data collected by performing a measurement from a point in time before the sample is placed at a measurement position (S2 and S3). If no significant peak is present in the graph, it is concluded that a sample introduction error has occurred (S11). By such a method, a higher level of qualitative determination accuracy can be achieved than in a conventional qualitative analysis using only the degree of similarity.

公开(公告)号：US20160111268A1

公开(公告)日：2016-04-21

申请号：US14514805

申请日：2014-10-15

Applicant: SHIMADZU CORPORATION

Inventor： Yutaro YAMAMURA

IPC: H01J49/00 ,  H01J49/26

CPC classification number: H01J49/0036

Abstract: A mass analysis device capable of reliably detecting the peak in a mass chromatogram of a given m/z is equipped with a control unit, which generates a mass chromatogram and total ion chromatogram. The control unit includes a determination unit which, using the total ion chromatogram, determines the start time and end time of the peak in the total ion chromatogram by searching for the peak based on maximum value of detected intensity and searching for peak start time and end time based on slope of change of detected intensity; and a detection unit, which detects the peak in the mass chromatogram by making the start time and end time of the peak in the mass chromatogram the same as the start time and end time of the peak in the total ion chromatogram.

Abstract translation: 能够可靠地检测给定m / z的质谱图中的峰的质量分析装置配备有产生质谱图和总离子色谱图的控制单元。 控制单元包括确定单元，其使用总离子色谱图，基于检测强度的最大值搜索峰值并搜索峰值开始时间和结束，确定总离子色谱图中峰的开始时间和结束时间 时间基于检测强度变化的斜率; 以及检测单元，其通过使质谱图中的峰的开始时间和结束时间与总离子色谱图中的峰的开始时间和结束时间相同来检测质谱图中的峰。