公开(公告)号：US20200222294A1

公开(公告)日：2020-07-16

申请号：US16827033

申请日：2020-03-23

Applicant: Shiseido Company, Ltd.

Inventor： Mio Nakamura ,  Kentaro KAJIYA ,  Shinichiro HAZE

IPC: A61K8/49 ,  A61K36/61 ,  A61K8/37 ,  A61Q19/08 ,  A61K31/22 ,  A61K31/351 ,  A61K8/92 ,  A61K36/738 ,  A61Q19/06

Abstract: The purpose of this invention is to find a novel fragrance component effective for prevention or control of swelling, lymphedema, skin aging or obesity from the viewpoint of activation of lymph vessel function by promotion of the expression of VEGFC. This invention provides a swelling improving agent, lymph vessel activator and VEGFC production promoter characterized by containing one or a plurality of components selected from the group consisting of rose oxide, citronellyl acetate and niaouli oil.

公开(公告)号：US20150290097A1

公开(公告)日：2015-10-15

申请号：US14442850

申请日：2013-11-14

Applicant: SHISEIDO COMPANY, LTD.

Inventor： Mio Nakamura ,  Shinichiro Haze ,  Akira Ito ,  Rumiko Fujiwara ,  Takako Shibata

IPC: A61K8/37 ,  A61Q19/02

CPC classification number: A61K8/37 ,  A61K2800/782 ,  A61Q19/02

Abstract: Provided is a novel drug capable of inhibiting excessive formation of melanin in skin and a skin whitening agent incorporated therewith.Phenylethyl cinnamate is incorporated as an active ingredient.

Abstract translation: 本发明提供能够抑制皮肤中过度形成黑色素的新型药物和与其结合的皮肤美白剂。 加入肉桂酸苯乙酯作为活性成分。

公开(公告)号：US11213472B2

公开(公告)日：2022-01-04

申请号：US16827033

申请日：2020-03-23

Applicant: Shiseido Company, Ltd.

Inventor： Mio Nakamura ,  Kentaro Kajiya ,  Shinichiro Haze

IPC: A61K36/00 ,  A61K8/49 ,  A61K36/61 ,  A61K8/37 ,  A61Q19/08 ,  A61K31/22 ,  A61K31/351 ,  A61K8/92 ,  A61K36/738 ,  A61Q19/06 ,  A61K31/122 ,  A61Q19/10 ,  A61Q19/00

Abstract: The purpose of this invention is to find a novel fragrance component effective for prevention or control of swelling, lymphedema, skin aging or obesity from the viewpoint of activation of lymph vessel function by promotion of the expression of VEGFC. This invention provides a swelling improving agent, lymph vessel activator and VEGFC production promoter characterized by containing one or a plurality of components selected from the group consisting of rose oxide, citronellyl acetate and niaouli oil.

公开(公告)号：US09278058B2

公开(公告)日：2016-03-08

申请号：US14442850

申请日：2013-11-14

Applicant: Shiseido Company, Ltd.

Inventor： Mio Nakamura ,  Shinichiro Haze ,  Akira Ito ,  Rumiko Fujiwara ,  Takako Shibata

IPC: A61K8/37 ,  A61Q19/02

CPC classification number: A61K8/37 ,  A61K2800/782 ,  A61Q19/02

Abstract: Provided is a novel drug capable of inhibiting excessive formation of melanin in skin and a skin whitening agent incorporated therewith.Phenylethyl cinnamate is incorporated as an active ingredient.

Abstract translation: 本发明提供能够抑制皮肤中过度形成黑色素的新型药物和与其结合的皮肤美白剂。 加入肉桂酸苯乙酯作为活性成分。

公开(公告)号：US20170281500A1

公开(公告)日：2017-10-05

申请号：US15625080

申请日：2017-06-16

Applicant: Shiseido Company, Ltd.

Inventor： Mio Nakamura ,  Kentaro KAJIYA ,  Shinichiro HAZE

IPC: A61K8/49 ,  A61Q19/08 ,  A61K31/351 ,  A61K8/37 ,  A61K31/22

CPC classification number: A61K8/498 ,  A61K8/37 ,  A61K8/922 ,  A61K31/22 ,  A61K31/351 ,  A61K36/61 ,  A61K36/738 ,  A61Q19/007 ,  A61Q19/06 ,  A61Q19/08 ,  A61Q19/10 ,  A61K2300/00

Abstract: The purpose of this invention is to find a novel fragrance component effective for prevention or control of swelling, lymphedema, skin aging or obesity from the viewpoint of activation of lymph vessel function by promotion of the expression of VEGFC. This invention provides a swelling improving agent, lymph vessel activator and VEGFC production promoter characterized by containing one or a plurality of components selected from the group consisting of rose oxide, citronellyl acetate and niaouli oil.