公开(公告)号：US20150335692A1

公开(公告)日：2015-11-26

申请号：US14818554

申请日：2015-08-05

Applicant: Shiseido Company, Ltd.

Inventor： Shunsuke IRIYAMA ,  Yukiko MATSUNAGA ,  Satoshi AMANO ,  Kenichi UMISHIO ,  Ken KUSAKARI ,  Takuya HIRUMA

IPC: A61K36/23 ,  A61K36/14 ,  A61K36/752 ,  A61K36/81 ,  A61K36/8962 ,  G01N33/573 ,  A61K36/725 ,  A61K8/97 ,  A61Q19/08 ,  A61Q19/00 ,  A61K9/00 ,  A61K36/185 ,  A61K36/8967

CPC classification number: A61K36/00 ,  A61K8/4946 ,  A61K8/66 ,  A61K8/97 ,  A61K9/0014 ,  A61K9/0019 ,  A61K9/0053 ,  A61K31/17 ,  A61K31/4184 ,  A61K36/14 ,  A61K36/18 ,  A61K36/185 ,  A61K36/23 ,  A61K36/725 ,  A61K36/73 ,  A61K36/75 ,  A61K36/752 ,  A61K36/81 ,  A61K36/896 ,  A61K36/8962 ,  A61K36/8967 ,  A61K2800/5922 ,  A61K2800/91 ,  A61K2800/92 ,  A61Q19/007 ,  A61Q19/08 ,  G01N33/573 ,  G01N2333/924 ,  G01N2500/04 ,  G01N2500/10

Abstract: Wrinkles are improved by applying an oral preparation, injection preparation or external skin preparation having a substance that controls heparanase as an active ingredient thereof.

Abstract translation: 通过应用具有控制肝素酶作为其活性成分的物质的口服制剂，注射制剂或外用皮肤制剂来改善皱纹。

公开(公告)号：US20230077466A1

公开(公告)日：2023-03-16

申请号：US17796092

申请日：2021-02-17

Applicant: SHISEIDO COMPANY, LTD. ,  NOF CORPORATION

Inventor： Tetsuya KANEMARU ,  Yoshihiro NISHIYAMA ,  Takuya HIRUMA ,  Yuka IWAHASHI ,  Takeshi YOSHIMURA ,  Mako IWASAKI

IPC: A61K8/36 ,  A61Q19/10

Abstract: The invention relates to particles of a calcium salt of a fatty acid having 12 to 22 carbon atoms, wherein the median size is 4.0 μm to 15.0 μm, the particle size digest A expressed by the following equation (1) satisfies the relation A≤2.0, and the average thickness is 350 to 800 nm. Particle size digest A=(D90−D10)/D50  equation (1) (Here, 4.0≤D50≤15.0.) D10: the 10% cumulative size (μm) of the fatty acid calcium salt particles on a volumetric basis D50: the median size (μm) of the fatty acid calcium salt particles on a volumetric basis D90: the 90% cumulative size (μm) of the fatty acid calcium salt particles on a volumetric basis

公开(公告)号：US20210228472A1

公开(公告)日：2021-07-29

申请号：US16305474

申请日：2017-05-29

Applicant: SHISEIDO COMPANY, LTD.

Inventor： TOMO OSAWA ,  Ayano MATSUO ,  Yuji SONOYAMA ,  Tomoko IKEDA ,  Shun KUBOTA ,  Mao HITOMI ,  Takuya HIRUMA ,  Tetsuya KANEMARU

IPC: A61K8/898 ,  A61K8/81 ,  A61K8/19 ,  A61Q1/12 ,  A61K8/891

Abstract: Provided is an elastomer that improves the skin feel of an inorganic powder. The elastomer according to the present invention is an elastomer comprising: (A) an amino group-containing silicone polymer; and (B) a carboxyl group-containing silicone polymer or a carboxyl group-containing acrylamide polymer, wherein a molar ratio Y/X between amino groups and carboxyl groups is within a range of 0.1 to 1.2, wherein Y denotes the molar amount of carboxyl groups contained in the component (B), and X denotes the molar amount of amino groups contained in the component (A).

公开(公告)号：US20170151134A1

公开(公告)日：2017-06-01

申请号：US15110908

申请日：2016-02-24

Applicant: SHISEIDO COMPANY, LTD.

Inventor： Motoharu KIMURA ,  Takuya HIRUMA ,  Tetsuya KANEMARU ,  Masayuki SHIRAO ,  Tomoko SATO ,  Toru YU

IPC: A61K8/11 ,  A61K8/55 ,  A61K8/26 ,  A61K8/25 ,  A61Q1/02 ,  A61K8/31

CPC classification number: A61K8/11 ,  A61K8/022 ,  A61K8/0254 ,  A61K8/21 ,  A61K8/25 ,  A61K8/26 ,  A61K8/31 ,  A61K8/55 ,  A61K2800/31 ,  A61K2800/412 ,  A61K2800/43 ,  A61K2800/63 ,  A61Q1/02

Abstract: An oil-enclosed powdery composition includes an oil-enclosable powder; further comprising; a platy powder, aluminum hydroxide coating the platy powder, having a surface of a specific surface area of at least 10 m2/g, and a fluorine compound coating the aluminum hydroxide; and an oil droplet having at least 50% by mass of hydrocarbon oil based on a total oil component and at least 2.0×10−2 N/m of a surface tension value as a total oil component; wherein the oil-enclosable powder encompassing the oil droplet is like powder having an average particle size of 10 to 150 μm and the oil-enclosed powdery composition is liquefiable by inunction.