公开(公告)号：US10758471B2

公开(公告)日：2020-09-01

申请号：US15536027

申请日：2015-10-27

Applicant: SHISEIDO COMPANY, LTD. ,  GOO CHEMICAL CO., LTD.

Inventor： Makoto Uyama ,  Kazuyuki Miyazawa ,  Takumi Watanabe ,  Mineo Abe ,  Masato Matsumura

IPC: C08F220/58 ,  C08F220/54 ,  C08F220/12 ,  A61K8/81 ,  A61Q1/00 ,  A61Q1/06 ,  C08F220/18 ,  A61K8/04 ,  A61Q1/10 ,  A61Q5/00 ,  A61Q19/00 ,  A61Q19/10

Abstract: Copolymers derived from hydrophobic monomers of formula (1), and hydrophilic monomers of formulas (2) and (3), are provided The copolymers are useful as gelling agents for oils used in cosmetics and cosmetic emulsions.

公开(公告)号：US10898426B2

公开(公告)日：2021-01-26

申请号：US16509901

申请日：2019-07-12

Applicant: SHISEIDO COMPANY, LTD.

Inventor： Reiji Miyahara ,  Takashi Oka ,  Makoto Uyama ,  Saori Tanabe ,  Tetsuro Yonezawa ,  Miho Yajima ,  Noriko Ohira ,  Saori Nishikawa

IPC: A61K8/86 ,  A61K8/06 ,  A61Q19/00 ,  A61K8/19 ,  A61K8/81 ,  A61K8/92 ,  A61K8/34 ,  A61K8/41 ,  A61K8/891 ,  A61K8/37

Abstract: The present invention addresses the problem of providing an α-gel formation composition and an α-gel composition that uses the α-gel formation composition, wherein said compositions are highly stable, do not deposit crystals, become more viscous over time, and, when used in a preparations for external use, are refreshing during application and have high skin-moisturizing action after application. A gel composition that includes a polyoxyethylene dialkyl ester and/or a polyoxyethylene dialkyl ether, a polyoxyethylene alkyl ester and/or a polyoxyethylene alkyl ether, and, preferably, a polyoxyethylene sterol ether and water.

公开(公告)号：US12090218B2

公开(公告)日：2024-09-17

申请号：US17618664

申请日：2020-02-28

Applicant: Shiseido Company, Ltd.

Inventor： Makoto Uyama ,  Takumi Watanabe ,  Ayano Matsuo

IPC: A61K8/06 ,  A61K8/81 ,  A61K8/92

CPC classification number: A61K8/064 ,  A61K8/8147 ,  A61K8/92 ,  A61K2800/805

Abstract: To provide a water-in-oil emulsified composition which highly encapsulates a water content, has high viscosity, and is excellent in emulsification stability.
The water-in-oil emulsified composition of the present disclosure comprises a dispersion medium comprising an oil content, and an oil-soluble copolymer having a monomer unit obtained from a specific hydrophilic monomer, and a monomer unit obtained from a specific hydrophobic monomer; and water droplets dispersed in the dispersion medium, wherein the oil content contains 60% by mass or more of polar oil with an IOB of 0.10 or more, and wherein the water droplets contain water and a surfactant, and the content of the water is 30% by mass or more based on the total amount of the composition.

公开(公告)号：US20200368119A1

公开(公告)日：2020-11-26

申请号：US16769815

申请日：2019-02-08

Applicant: Shiseido Company, Ltd.

Inventor： Makoto Uyama

IPC: A61K8/06 ,  A61K8/895 ,  A61K8/86 ,  A61K8/34 ,  A61Q19/00

Abstract: The invention provides a novel oil-in-water fine emulsion cosmetic composition that is stable.The oil-in-water fine emulsion cosmetic composition of the invention, containing: a dispersion medium that contains water and a divalent glycol; an oil component that is dispersed in the dispersion medium and contains a silicone oil and a hydrocarbon oil; a carboxy-modified silicone-based surfactant represented by the following Formula 1; at least one selected from a higher alcohol and a higher fatty acid that are liquid at 25° C. and have 16 to 22 carbon atoms; and a nonionic surfactant that contains a polyoxyethylene chain and has an HLB of 12 to 17, the cosmetic composition having oil droplets of an average particle size of 150 nm or smaller: wherein, at least one of R1 to R3 is a substituent represented by —O—Si(R4)3 wherein R4 is at least one selected from an alkyl group having 1 to 6 carbon atoms and a phenyl group and, when any one of R1 to R3 is not the substituent, the others are substituted or unsubstituted monovalent hydrocarbon groups that are optionally the same or different; A is a linear or branched alkylene group represented by CqH2q wherein q is an integer of 0 to 20, and M is a metal atom or an organic cation.

公开(公告)号：US11033479B2

公开(公告)日：2021-06-15

申请号：US16073201

申请日：2017-01-06

Applicant: SHISEIDO COMPANY, LTD.

Inventor： Reiji Miyahara ,  Tetsuro Yonezawa ,  Takashi Oka ,  Makoto Uyama ,  Saori Tanabe

IPC: A61K8/86 ,  A61K8/34 ,  A61Q19/00 ,  C08L71/02 ,  A61K8/39 ,  A61K8/04 ,  A61K8/36 ,  A61Q17/04 ,  A61K8/06

Abstract: The present invention provides an α-gel forming composition and an α-gel composition that uses an α-gel formation composition that is highly stable and that does not become colored or deposit crystals, etc. over time. An α-gel composition includes (A) 25-50 mass % of one or more higher aliphatic alcohol and/or higher fatty acid has 16 or more carbons, (B) 40-70 mass % of a specific polyoxyethylene sterol ether, and (C) 5-20 mass % of a specific polyoxyethylene dialkyl ester and/or ether. The α-gel composition is generated by adding water.

公开(公告)号：US11052030B2

公开(公告)日：2021-07-06

申请号：US16576229

申请日：2019-09-19

Applicant: SHISEIDO COMPANY, LTD.

Inventor： Makoto Uyama ,  Reiji Miyahara

IPC: A61K8/58 ,  A61K8/31 ,  A61K8/06 ,  A61K8/891 ,  A61K8/89 ,  A61K8/39 ,  A61Q19/00 ,  A61Q5/00 ,  A61K8/34 ,  A61K8/86

Abstract: A method of preparing a fine oil-in-water emulsion comprising an oil phase based on silicone and/or hydrocarbon oils, in which the oil phase particles have an average particle size of 150 nm or less. The emulsion is stabilized by a carboxy-modified silicone in combination with a C16 to 22 higher alcohol; a nonionic surfactant having a POE chain and an HLB of 5 to 10; and a dihydric glycol. The emulsions can be prepared without the use of a high-pressure emulsifying apparatus.

公开(公告)号：US20200009036A1

公开(公告)日：2020-01-09

申请号：US16576229

申请日：2019-09-19

Applicant: SHISEIDO COMPANY, LTD.

Inventor： Makoto Uyama ,  Reiji Miyahara

IPC: A61K8/58 ,  A61K8/31 ,  A61K8/891 ,  A61K8/06 ,  A61K8/34 ,  A61K8/86 ,  A61Q19/00

Abstract: A method of preparing a fine oil-in-water emulsion comprising an oil phase based on silicone and/or hydrocarbon oils, in which the oil phase particles have an average particle size of 150 nm or less. The emulsion is stabilized by a carboxy-modified silicone in combination with a C16 to 22 higher alcohol; a nonionic surfactant having a POE chain and an HLB of 5 to 10; and a dihydric glycol. The emulsions can be prepared without the use of a high-pressure emulsifying apparatus.

公开(公告)号：US20190350833A1

公开(公告)日：2019-11-21

申请号：US16509901

申请日：2019-07-12

Applicant: SHISEIDO COMPANY, LTD.

Inventor： REIJI MIYAHARA ,  Takashi Oka ,  Makoto Uyama ,  Saori Tanabe ,  Tetsuro Yonezawa ,  Miho Yajima ,  Noriko Ohira ,  Saori Nishikawa

IPC: A61K8/86 ,  A61K8/06 ,  A61Q19/00 ,  A61K8/19 ,  A61K8/81 ,  A61K8/34 ,  A61K8/41 ,  A61K8/891 ,  A61K8/37 ,  A61K8/92

Abstract: The present invention addresses the problem of providing an α-gel formation composition and an α-gel composition that uses the α-gel formation composition, wherein said compositions are highly stable, do not deposit crystals, become more viscous over time, and, when used in a preparations for external use, are refreshing during application and have high skin-moisturizing action after application. A gel composition that includes a polyoxyethylene dialkyl ester and/or a polyoxyethylene dialkyl ether, a polyoxyethylene alkyl ester and/or a polyoxyethylene alkyl ether, and, preferably, a polyoxyethylene sterol ether and water.