公开(公告)号：US20200087248A1

公开(公告)日：2020-03-19

申请号：US16489474

申请日：2018-04-19

申请人： SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD.

发明人： Jiawang ZHU ,  Zhiquan SONG ,  Long YANG ,  Rui LI ,  Shuai ZHANG ,  Lin ZHOU ,  Mingliang ZHAO ,  Zujian TANG ,  Wei ZHONG ,  Hong ZENG ,  Hongmei SONG ,  Xin ZHOU ,  Yuting TANG ,  Xiao HU ,  Lichun WANG ,  Jingyi WANG

IPC分类号： C07C235/56 ,  C07C231/14 ,  C07D217/04 ,  C07D277/24 ,  C07D209/44 ,  C07D211/16 ,  C07D239/26 ,  C07D235/18 ,  C07D277/66 ,  C07C211/24 ,  C07D309/14 ,  C07D213/40 ,  C07D319/16

摘要： The present invention relates to a fluoroallylamine derivative and use thereof. In particular, the present invention relates to a compound as shown in Formula I, a prodrug, an isomer, an isotope-labeled compound, a solvate or a pharmaceutically acceptable salt thereof, which has VAP-1/SSAO inhibitory activity, and can be used for treating a disease associated with VAP-1/SSAO overactivity.