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公开(公告)号:US20160369240A1
公开(公告)日:2016-12-22
申请号:US15122311
申请日:2015-03-03
发明人: Nan LIN , Joaquina MASCARENHAS , Audrey CHANG , David ONIONS , Henry GEORGE , Kevin KAYSER
CPC分类号: C12N5/0682 , C12N5/00 , C12N9/1051 , C12N2501/724 , C12N2510/02 , C12N2720/12011 , C12N2750/14311 , C12Y204/01101 , C12Y204/01144 , C12Y204/01155
摘要: The present invention provides mammalian cell lines that have been genetically engineered causing such cell lines to be resistant to viral entry and/or propagation, and provides methods of using said cell lines to reduce or prevent viral contamination of biologic production systems.
摘要翻译: 本发明提供已经进行遗传工程改造的哺乳动物细胞系,使得这种细胞系能够抵抗病毒进入和/或繁殖,并提供使用所述细胞系减少或防止生物制备系统的病毒污染的方法。