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公开(公告)号:US20220235011A1
公开(公告)日:2022-07-28
申请号:US17594754
申请日:2020-05-29
发明人: Kyungjin KIM , Kwangrok KIM , Uk-Il KIM , Hyung Tae BANG , Seul Ki LEE , Kwan-Young JEONG , Seung Kyu KANG , Heejung JUNG , Sang Dal RHEE , Won Hoon JUNG , Jun Mi LEE
IPC分类号: C07D237/32 , C07D401/10 , C07D405/04 , C07D401/04 , C07D403/04
摘要: Provided is a phthalazinone compound, or a racemate, steroisomer or pharmaceutically acceptable salt thereof; a pharmaceutical composition for the prevention or treatment of Sirt6-associated diseases, including as an active ingredient, a phthalazinone compound, or a racemate, steroisomer or pharmaceutically acceptable salt thereof; and a method for treating Sirt6-associated diseases including administering a phthalazinone compound, or a racemate, steroisomer or pharmaceutically acceptable salt thereof to a subject in need.
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公开(公告)号:US20180362538A1
公开(公告)日:2018-12-20
申请号:US16060250
申请日:2016-12-01
申请人: St Pharm Co., LTD
发明人: Kyungjin KIM , Uk-Il KIM , Ji Hye YOON
IPC分类号: C07D491/052 , A61P35/00
CPC分类号: C07D491/052 , A61P35/00
摘要: The present invention relates to a novel dihydropyranopyrimidinone derivative, a tautomer thereof, a stereoisomer thereof and their mixture, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating a tankyrase-related disease, which contains the same as an active ingredient.
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公开(公告)号:US20180214559A1
公开(公告)日:2018-08-02
申请号:US15746133
申请日:2015-07-20
申请人: ST PHARM CO., LTD.
发明人: Kyungjin KIM , Jisuk YUN , Hyukjun JUNG , Myungyun LEE , Hwajung NAM , Ok-cheol JEON
IPC分类号: A61K47/54 , A61K9/00 , A61K38/28 , A61K31/727
CPC分类号: A61K47/554 , A61K9/0053 , A61K31/727 , A61K38/26 , A61K38/28 , C07J9/005 , C07J41/0061 , C08B37/0075
摘要: The present invention provides a novel drug delivery conjugated moiety for oral administration of a drug that is not suitable for oral administration or a pharmaceutically acceptable salt thereof. When the drug delivery conjugated moiety of the present invention or a pharmaceutically acceptable salt thereof is combined with a drug, which is not suitable for oral administration, and is administered orally, it exhibits an excellent absorption rate without decreasing the biological activities of the drug. Moreover, the drug delivery conjugated moiety of the present invention or a pharmaceutically acceptable salt thereof can be easily prepared in a few steps, which is very advantageous in terms of mass production.
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公开(公告)号:US20220054644A1
公开(公告)日:2022-02-24
申请号:US17516977
申请日:2021-11-02
申请人: ST PHARM CO., LTD
发明人: Kyungjin KIM , Jisuk YUN , Hyukjun JUNG , Myungyun LEE , Hwajung NAM , Ok-cheol JEON
摘要: The present invention provides a novel drug delivery conjugated moiety for oral administration of a drug that is not suitable for oral administration or a pharmaceutically acceptable salt thereof. When the drug delivery conjugated moiety of the present invention or a pharmaceutically acceptable salt thereof is combined with a drug, which is not suitable for oral administration, and is administered orally, it exhibits an excellent absorption rate without decreasing the biological activities of the drug. Moreover, the drug delivery conjugated moiety of the present invention or a pharmaceutically acceptable salt thereof can be easily prepared in a few steps, which is very advantageous in terms of mass production.
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公开(公告)号:US20210040135A1
公开(公告)日:2021-02-11
申请号:US16963900
申请日:2019-01-24
申请人: St Pharm Co., Ltd.
发明人: Kyungjin KIM , Meehyein KIM , UK-II KIM , Yun Young GO , Hwajung NAM , Hyung BANG , Jin Soo SHIN , Jihye YOON , Yejin JANG
IPC分类号: C07H19/067
摘要: The present disclosure relates to a novel nucleoside or nucleotide derivative, a racemate thereof, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition for preventing or treating viral infection-associated diseases, containing the same as an active ingredient.
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公开(公告)号:US20200377498A1
公开(公告)日:2020-12-03
申请号:US16497255
申请日:2017-03-24
申请人: ST PHARM CO., LTD.
发明人: Bong Jin KIM , Ill Young LEE , Jae Hak KIM , Hong Suk SHIN , Jong Chan SON , Chong-Kyo LEE , Kyungjin KIM , Uk-Il KIM , Hwa Jung NAM
IPC分类号: C07D471/04 , A61P31/18
摘要: Provided is a novel pyrrolopyridine compound represented by Chemical Formula I, a racemate or a stereoisomer thereof, or a pharmaceutically acceptable salt thereof; and to a method for preparing the same. A compound represented by Chemical Formula I shows high selectivity and antiviral activity against human immunodeficiency virus (HIV), with low toxicity; therefore, it is useful as a therapeutic agent for viral infection, in particular, HIV infection.
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