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Patent Agency Ranking
公开(公告)号：US20220023172A1
公开(公告)日：2022-01-27
申请号：US17297349
申请日：2019-11-27
Applicant: Kristina TRUJILLO , Katie UILK , David L. VANDER JAGT , Lorraine M. DECK , STC.UNM , K&K BIOTECH
Inventor： Kristina Trujillo , Katie Uilk , David L. Vander Jagt , Lorraine M. Deck
Abstract: The present invention relates to substituted stilbenes and dienones which exhibit unexpected dual activity, as inhibitors of NFKB and as agonists (activators) of Nrf2. In particular, these compounds show dual activity and it has been discovered that these compounds are particularly useful in the treatment of certain cosmetic applications and in rejuvenating and beautifying skin and other keratinous tissue of a subject in need. Cosmetic compositions and methods of using said compositions in combination with other components are disclosed herein.
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公开(公告)号：US20150011494A1
公开(公告)日：2015-01-08
申请号：US14449599
申请日：2014-08-01
Applicant: STC.UNM
Inventor： David L. Vander Jagt , Lorraine M. Deck , Steve F. Abcouwer , Robert A. Orlando , Robert E. Royer , Waylon M. Weber , Ekaterina V. Bobrovnikova-Marjon , Lucy A. Hunsaker
IPC: C07C49/255 , C07D213/50 , G01N33/50 , C07C49/235 , A61K45/06 , A61K31/121 , A61K31/444
CPC classification number: C07C49/255 , A61K31/12 , A61K31/121 , A61K31/137 , A61K31/235 , A61K31/277 , A61K31/282 , A61K31/336 , A61K31/337 , A61K31/444 , A61K31/704 , A61K45/06 , C07C49/235 , C07D213/50 , G01N33/5023 , G01N33/5058 , G01N2500/10 , A61K2300/00
Abstract: Curcumin analogues and methods are provided for treatment of disease.
Abstract translation: 提供姜黄素类似物和方法用于治疗疾病。
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公开(公告)号：US09187397B2
公开(公告)日：2015-11-17
申请号：US14449599
申请日：2014-08-01
Applicant: STC.UNM
Inventor： David L. Vander Jagt , Lorraine M. Deck , Steve F. Abcouwer , Robert A. Orlando , Robert E. Royer , Waylon M. Weber , Ekaterina V. Bobrovnikova-Marjon , Lucy A. Hunsaker
IPC: A61K31/44 , C07C49/255 , A61K31/12 , A61K31/137 , A61K31/235 , A61K31/277 , A61K31/282 , A61K31/336 , A61K31/337 , A61K31/704 , A61K45/06 , A61K31/121 , A61K31/444 , C07C49/235 , C07D213/50 , G01N33/50
CPC classification number: C07C49/255 , A61K31/12 , A61K31/121 , A61K31/137 , A61K31/235 , A61K31/277 , A61K31/282 , A61K31/336 , A61K31/337 , A61K31/444 , A61K31/704 , A61K45/06 , C07C49/235 , C07D213/50 , G01N33/5023 , G01N33/5058 , G01N2500/10 , A61K2300/00
Abstract: Curcumin analogues and methods are provided for treatment of disease.
Abstract translation: 提供姜黄素类似物和方法用于治疗疾病。
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公开(公告)号：US20190160021A1
公开(公告)日：2019-05-30
申请号：US16204085
申请日：2018-11-29
Applicant: STC.UNM
Inventor： David L. Vander Jagt , Lorraine M. Deck , Robert E. Royer
IPC: A61K31/035 , A61K31/09 , A61K31/05 , A61K31/122 , A61K45/06 , A61P35/00 , A61P17/00
Abstract: The present invention relates to substituted stilbenes and dienones which exhibit unexpected dual activity, as inhibitors of NFκB and as agonists (activators) of Nrf2. In particular, these compounds show dual activity and makes them particularly useful in the treatment of inflammation, including chronic inflammation and a number of related chronic disease states and conditions, including neurological diseases, including Alzheimer's, Alzheimer's prodrome and mild cognitive impairment, and other diseases and conditions, such as Parkinson's disease, depression, bipolar disorders and autism spectrum disorders. Compounds, pharmaceutical compositions and methods of treatment are described.
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公开(公告)号：US20160039734A1
公开(公告)日：2016-02-11
申请号：US14887780
申请日：2015-10-20
Applicant: STC.UNM
Inventor： David L. Vander Jagt , Lorraine M. DECK , Steve F. ABCOUWER , Robert A. ORLANDO , Robert E. ROYER , Waylon M. WEBER , Ekaterina V. BOBROVNIKOVA-MARJON , Lucy A. HUNSAKER
IPC: C07C49/255 , C07D213/50
CPC classification number: C07C49/255 , A61K31/12 , A61K31/121 , A61K31/137 , A61K31/235 , A61K31/277 , A61K31/282 , A61K31/336 , A61K31/337 , A61K31/444 , A61K31/704 , A61K45/06 , C07C49/235 , C07D213/50 , G01N33/5023 , G01N33/5058 , G01N2500/10 , A61K2300/00
Abstract: Curcumin analogues and methods are provided for treatment of disease.
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