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Patent Agency Ranking
公开(公告)号：US20150125898A1
公开(公告)日：2015-05-07
申请号：US14596926
申请日：2015-01-14
Applicant: STC.UNM
Inventor： Graham Timmins , Terry Wu , Seong Won Choi
IPC: C12Q1/04 , C07B59/00 , C07C275/16
CPC classification number: C12Q1/04 , C07B59/001 , C07B2200/05 , C07B2200/07 , C07C275/16 , C12Q2304/46 , C12Q2304/48
Abstract: The present invention is directed to the use of isotopically labeled citrulline for diagnosing the presence or absence of a bacterial infection in the lungs of a patient.
Abstract translation: 本发明涉及同位素标记的瓜氨酸用于诊断患者肺中细菌感染的存在或不存在的用途。
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公开(公告)号：US20180296505A1
公开(公告)日：2018-10-18
申请号：US16015415
申请日：2018-06-22
Applicant: STC.UNM
Inventor： Graham Timmins , Seong Won Choi
IPC: A61K31/16 , A61K9/00 , A61K31/4965 , A61K45/06
Abstract: In one embodiment, the invention provides a method of treating a subject who suffers from, or who is suspected of suffering from, a Mycobacterium infection, the method comprising administering to the subject a therapeutically effective amount of a urease inhibitor, optionally in combination with one or more anti-mycobacterial agents.
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公开(公告)号：US20170056345A1
公开(公告)日：2017-03-02
申请号：US15119563
申请日：2015-02-18
Applicant: STC.UNM
Inventor： Graham Timmins , Seong Won Choi
IPC: A61K31/16 , A61K9/00 , A61K45/06 , A61K31/4965
CPC classification number: A61K31/16 , A61K9/0075 , A61K31/4965 , A61K45/06 , A61K2300/00
Abstract: In one embodiment, the invention provides a method of treating a subject who suffers from, or who is suspected of suffering from, a Mycobacterium infection, the method comprising administering to the subject a therapeutically effective amount of a urease inhibitor, optionally in combination with one or more anti-mycobacterial agents.
Abstract translation: 在一个实施方案中，本发明提供了治疗患有或被怀疑患有分枝杆菌感染的受试者的方法，所述方法包括向受试者施用治疗有效量的脲酶抑制剂，任选地与一种 或更多的抗分枝杆菌剂。
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4.发明授权Magnetodynamic activation of 13 C-acyl isoniazid and isoniazid and ethionamide derivatives 有权13 C-酰基异烟肼和异烟肼和乙二胺衍生物的磁动力学活化公开(公告)号：US09579381B2
公开(公告)日：2017-02-28
申请号：US14426543
申请日：2013-09-06
Applicant: STC.UNM
Inventor： Graham Timmins , Seong Won Choi
IPC: A61K31/4409 , A61K41/00
CPC classification number: A61K41/0052 , A61K31/4409
Abstract: The invention provides method of treating a subject suffering from, or at risk of developing, a Mycobacterium infection by administering to the subject a therapeutically-effective amount of isotopically labeled isoniazid and/or ethionamide, or an analog, derivative or prodrug thereof, and exposing the subject to a magnetic field.
Abstract translation: 本发明提供了通过向受试者施用治疗有效量的同位素标记的异烟肼和/或乙硫异烟胺或其类似物，衍生物或前药，以及暴露于受试者的方法，治疗患有或有发展为分枝杆菌感染风险的受试者 受到磁场的影响。
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5.发明申请MAGNETODYNAMIC ACTIVATION OF 13C-ACYL ISONIAZID AND ISONIAZID AND ETHIONAMIDE DERIVATIVES 有权13C-ACYL异亮氨酸和异亮氨酸和酰胺衍生物的磁活性激活公开(公告)号：US20150246126A1
公开(公告)日：2015-09-03
申请号：US14426543
申请日：2013-09-06
Applicant: Graham TIMMINS , Seong Won CHOI , STC.UNM
Inventor： Graham Timmins , Seong Won Choi
IPC: A61K41/00 , A61K31/4409
CPC classification number: A61K41/0052 , A61K31/4409
Abstract: The invention provides method of treating a subject suffering from, or at risk of developing, a Mycobacterium infection by administering to the subject a therapeutically-effective amount of isotopically labeled isoniazid and/or ethionamide, or an analog, derivative or prodrug thereof, and exposing the subject to a magnetic field.
Abstract translation: 本发明提供了通过向受试者施用治疗有效量的同位素标记的异烟肼和/或乙硫异烟胺或其类似物，衍生物或前药，以及暴露于受试者的方法，治疗患有或有发展为分枝杆菌感染风险的受试者 受到磁场的影响。
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