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公开(公告)号：US11491215B2
公开(公告)日：2022-11-08
申请号：US16543463
申请日：2019-08-16
Applicant: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC , STC.UNM
Inventor： Nicholas Fischer , Amy Rasley , Terry Wu , Julie Lovchik
Abstract: Provided herein are antigenic combinations and related compositions, methods and systems for immunizing a host from an infection caused by Francisella bacterium. The antigenic combination comprises an antigenic polysaccharide component from a Francisella bacterium capable of triggering a humoral immune response in an individual, a protein antigen component from the Francisella bacterium capable of triggering a cellular immune response in the individual, and an adjuvant, the antigenic Francisella polysaccharide component, the Francisella protein antigen component and the adjuvant are in a suitable amount to immunize an individual against the Francisella bacterium.
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公开(公告)号：US20150125898A1
公开(公告)日：2015-05-07
申请号：US14596926
申请日：2015-01-14
Applicant: STC.UNM
Inventor： Graham Timmins , Terry Wu , Seong Won Choi
IPC: C12Q1/04 , C07B59/00 , C07C275/16
CPC classification number: C12Q1/04 , C07B59/001 , C07B2200/05 , C07B2200/07 , C07C275/16 , C12Q2304/46 , C12Q2304/48
Abstract: The present invention is directed to the use of isotopically labeled citrulline for diagnosing the presence or absence of a bacterial infection in the lungs of a patient.
Abstract translation: 本发明涉及同位素标记的瓜氨酸用于诊断患者肺中细菌感染的存在或不存在的用途。
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公开(公告)号：US10183068B2
公开(公告)日：2019-01-22
申请号：US15311298
申请日：2015-05-15
Applicant: STC.UNM
Inventor： Pavan Muttil , Denis Wafula , Terry Wu , Nitesh Kunda , Dominique N. Price
Abstract: This disclosure describes, generally, compositions and methods related to thermostable vaccine formulations, their storage, and their use. Generally, the thermostable vaccine formulations can be in the form of a dry powder. The dry powder formulations can increase the length of time that the vaccine remains viable under non-refrigerated, ambient temperature conditions.
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