公开(公告)号：US11337617B2

公开(公告)日：2022-05-24

申请号：US16037328

申请日：2018-07-17

Applicant: STMicroelectronics S.r.l.

Inventor： Francesco Rundo ,  Piero Fallica ,  Sabrina Conoci ,  Salvatore Petralia ,  Massimo Cataldo Mazzillo

IPC: G06K9/00 ,  A61B5/00 ,  G16H10/60 ,  A61B5/349 ,  A61B5/024 ,  G16H50/00 ,  G06V40/10

Abstract: In an embodiment, PhotoPlethysmoGraphy (PPG) signals are processed by detecting peaks and valleys in the PPG signal, segmenting the PPG signal to provide a time series of PPG waveforms located between two subsequent valleys in the PPG signal, applying to the waveforms in the time series pattern recognition with respect to a reference PPG waveform pattern produced based on a mathematical model of the PPG signal by assigning to the waveforms in the time series a recognition score. A resulting PPG signal is produced by retaining the waveforms in the time series having an assigned recognition score reaching a recognition threshold, and discarding the waveforms in the time series having an assigned recognition score failing to reach the recognition threshold.

公开(公告)号：US08766006B2

公开(公告)日：2014-07-01

申请号：US13858558

申请日：2013-04-08

Applicant: STMicroelectronics S.r.l.

Inventor： Sabrina Conoci ,  Salvatore Petralia ,  Salvatore Sortino

IPC: C07C211/52 ,  C07C211/48 ,  C07C15/00 ,  C07F7/00 ,  C07C323/29 ,  B01J19/08 ,  A61K31/136 ,  A61K31/137

CPC classification number: C07C211/52 ,  A61K31/04 ,  A61K33/00 ,  B01J19/123 ,  B01J2219/089 ,  C01B21/24 ,  C07C323/29 ,  A61K2300/00

Abstract: The present invention relates to the use of a nitroaniline derivative of Formula I for the production of nitric oxide and for the preparation of a medicament for the treatment of a disease wherein the administration of nitric oxide is beneficial. The present invention furthermore relates to a method for the production of NO irradiating a nitroaniline derivative of Formula I, a kit comprising a nitroaniline derivative of Formula I and a carrier and to a system comprising a source of radiations and a container associated to a nitroaniline derivative of Formula I. In Formula I, R and RI are each independently hydrogen or a C1-C3 alkyl group; RII is hydrogen or an alkyl group.

Abstract translation: 本发明涉及式I的硝基苯胺衍生物在制备一氧化氮中的用途以及用于制备治疗其中一氧化氮的给药有益的药物的用途。 本发明还涉及一种用于制备辐射式I的硝基苯胺衍生物的NO的方法，该试剂盒包含式I的硝基苯胺衍生物和载体，以及包含辐射源和与硝基苯胺衍生物相关的容器的体系 在式I中，R 1和R 2各自独立地为氢或C 1 -C 3烷基; RII是氢或烷基。