公开(公告)号：US20190169029A1

公开(公告)日：2019-06-06

申请号：US16208926

申请日：2018-12-04

申请人： Ascend Performance Materials Operations LLC

发明人： Gregory E. Bush ,  Darrick K. Elmore ,  Mikhail I. Khramov

IPC分类号： C01B21/38 ,  C01B21/24 ,  C01B21/36 ,  B01J12/00 ,  B01J19/00 ,  C07C51/31

CPC分类号： C01B21/38 ,  B01J12/005 ,  B01J19/0013 ,  C01B21/24 ,  C01B21/36 ,  C07C51/316 ,  C07C55/14

摘要： Described herein is an improved conversion of nitrous oxide (N2O) present as a by-product in a chemical process to NOx which can be further converted to a useful compound or material, such as nitric acid.

公开(公告)号：US20180113112A1

公开(公告)日：2018-04-26

申请号：US15564820

申请日：2016-04-08

申请人： The Regents of the University of California

发明人： Hua Cai ,  Kimberly Howard-Quijano ,  Aman Mahajan ,  Ji Youn Youn

IPC分类号： G01N33/49

CPC分类号： G01N33/4925 ,  A61B5/145 ,  A61B5/7275 ,  C01B21/24 ,  G01N2800/326 ,  G01N2800/50 ,  G01N2800/7009

摘要： Disclosed herein are methods of using serum nitric oxide levels to diagnose subjects as having or likely to develop a post-operative complication.

公开(公告)号：US09872953B2

公开(公告)日：2018-01-23

申请号：US14388482

申请日：2013-03-28

申请人： The Regents of the University of Michigan

发明人： Lajos Hofler ,  Mark E. Meyerhoff ,  Dipankar Koley

IPC分类号： A61M5/14 ,  A61M25/00 ,  A61K33/00 ,  C01B21/24

CPC分类号： A61M5/14 ,  A61K33/00 ,  A61M25/00 ,  A61M25/0043 ,  A61M2025/0057 ,  A61M2202/0275 ,  A61M2205/0233 ,  A61M2205/0272 ,  C01B21/24

摘要： A nitric oxide delivery device includes a housing that is permeable to nitric oxide. A working electrode (which is a copper-containing conductive material or a base material coated with a copper-containing conductive material) is positioned inside of the housing. A conductive lead is electrically connected to the working electrode and extends outside of the housing. A reference electrode and/or a counter electrode is electrically isolated from the working electrode. The reference electrode and/or the counter electrode has a first portion that is inside of the housing and a second conductive portion that is outside of the housing. A source of nitrite ions is to be contained within the housing such that it is in contact with the working electrode.

公开(公告)号：US09744510B2

公开(公告)日：2017-08-29

申请号：US15194861

申请日：2016-06-28

申请人： SYK TECHNOLOGIES, LLC

发明人： J. W. Randolph Miller ,  Christie W. Jones

IPC分类号： B01J7/00 ,  C01B21/24 ,  A61K33/00 ,  A61M16/12

CPC分类号： B01J7/00 ,  A61K33/00 ,  A61M16/12 ,  B01J2219/00121 ,  B01J2219/00135 ,  C01B21/24

摘要： An apparatus to generate nitric oxide is disclosed in one embodiment in accordance with the invention as including a heat source and a vessel containing the heat source. A tablet may be placed within the vessel such that it is in thermal communication with the heat source to receive heat therefrom. The tablet may contain reactants that are substantially non-deliquescent and form nitric oxide in response to heat from the heat source.

公开(公告)号：US20170182471A1

公开(公告)日：2017-06-29

申请号：US15229105

申请日：2016-08-04

申请人： GENO LLC

发明人： David H. Fine ,  David R. Rounbehler ,  Gregory Vasquez ,  Brian Johnson

IPC分类号： B01J12/00 ,  A61K33/00 ,  A61M16/10 ,  C01B21/24 ,  A62B7/08

CPC分类号： B01J12/007 ,  A61K33/00 ,  A61M16/10 ,  A61M16/122 ,  A61M2016/1025 ,  A61M2202/0007 ,  A61M2202/0078 ,  A61M2202/0275 ,  A61M2205/07 ,  A61M2205/12 ,  A62B7/08 ,  C01B21/24

摘要： A nitric oxide delivery system, which includes a gas bottle having nitrogen dioxide in air, converts nitrogen dioxide to nitric oxide and employs a surface-active material, such as silica gel, coated with an aqueous solution of antioxidant, such as ascorbic acid. A nitric oxide delivery system may be used to generate therapeutic gas including nitric oxide for use in delivering the therapeutic gas to a mammal.

公开(公告)号：US09675923B2

公开(公告)日：2017-06-13

申请号：US13593914

申请日：2012-08-24

申请人： Jeffrey R. Long ,  Eric D. Bloch ,  Leslie Murray

发明人： Jeffrey R. Long ,  Eric D. Bloch ,  Leslie Murray

IPC分类号： C07C11/04 ,  C07C11/06 ,  C07C29/50 ,  C07C7/12 ,  C07C45/32 ,  C07C9/04 ,  C07D301/04 ,  C01B21/22 ,  C01B21/24 ,  B01D53/02 ,  C01B13/02 ,  C07C45/35 ,  C10L3/10 ,  B01J31/16 ,  B01J31/22

CPC分类号： B01D53/02 ,  B01D2253/204 ,  B01D2256/12 ,  B01D2256/24 ,  B01D2257/102 ,  B01D2257/404 ,  B01D2257/7022 ,  B01J31/1691 ,  B01J31/2239 ,  B01J2231/70 ,  B01J2531/842 ,  C01B13/0262 ,  C01B21/22 ,  C01B21/24 ,  C07C7/12 ,  C07C29/50 ,  C07C45/32 ,  C07C45/35 ,  C07D301/04 ,  C10L3/101 ,  Y02C20/10 ,  Y02P20/153 ,  Y02P20/51 ,  Y02P20/52 ,  C07C49/08 ,  C07C11/02 ,  C07C11/04 ,  C07C11/06 ,  C07C9/04 ,  C07C31/08 ,  C07C31/10

摘要： Fe2(dobdc) has a metal-organic framework with a high density of coordinatively-unsaturated FeII centers lining the pore surface. It can be effectively used to separate O2 from N2 and in a number of additional separation applications based on selective, reversible electron transfer reactions. In addition to being an effective O2 separation material, it can be used for many other processes, including paraffin/olefin separation, nitric oxide/nitrous oxide separation, acetylene storage, and as an oxidation catalyst.

公开(公告)号：US20170157590A1

公开(公告)日：2017-06-08

申请号：US15433854

申请日：2017-02-15

申请人： HONDA MOTOR CO., LTD.

发明人： Avetik R. HARUTYUNYAN

IPC分类号： B01J20/20 ,  C01B13/02 ,  C01B21/24 ,  C01C1/00 ,  B01J23/745 ,  G01N27/12 ,  B01J35/00 ,  B01J37/04 ,  B01J37/10 ,  B01J20/30 ,  B01J20/34 ,  C07C7/12 ,  C01B3/00 ,  B01J21/04

CPC分类号： B01D53/04 ,  B01D53/02 ,  B01D53/32 ,  B01D2253/102 ,  B01D2253/25 ,  B01D2253/304 ,  B01D2253/34 ,  B01D2257/102 ,  B01D2257/104 ,  B01D2257/108 ,  B01D2257/404 ,  B01D2257/502 ,  B01D2257/504 ,  B01D2257/7025 ,  B01J20/20 ,  B01J20/205 ,  B01J20/3085 ,  B01J20/324 ,  B01J20/3295 ,  B01J20/3441 ,  B01J21/04 ,  B01J23/745 ,  B01J35/0006 ,  B01J37/0236 ,  B01J37/04 ,  B01J37/10 ,  B82Y15/00 ,  B82Y30/00 ,  B82Y40/00 ,  C01B3/0021 ,  C01B3/0026 ,  C01B3/0031 ,  C01B3/0042 ,  C01B3/0078 ,  C01B13/02 ,  C01B21/24 ,  C01B32/162 ,  C01B32/40 ,  C01B32/50 ,  C01B2202/02 ,  C01B2202/22 ,  C01C1/006 ,  C07C7/12 ,  G01N27/125 ,  Y02C10/08 ,  Y02C20/20 ,  Y02E60/325 ,  Y02E60/327 ,  Y02P20/152 ,  Y02P20/156 ,  Y10S977/75 ,  Y10S977/843 ,  Y10S977/932 ,  Y10S977/957

摘要： The electronic structure of nanowires, nanotubes and thin films deposited on a substrate is varied by doping with electrons or holes. The electronic structure can then be tuned by varying the support material or by applying a gate voltage. The electronic structure can be controlled to absorb a gas, store a gas, or release a gas, such as hydrogen, oxygen, ammonia, carbon dioxide, and the like.

公开(公告)号：US20170065630A1

公开(公告)日：2017-03-09

申请号：US15268560

申请日：2016-09-17

申请人： NIOXX LLC

发明人： Cheng-Shing Chen ,  Ferid Murad ,  Kenneth A. Smith ,  WIlliam A. Seitz ,  William J. Merrell ,  Alexandru T. Balaban

IPC分类号： A61K33/00 ,  A61K9/70 ,  A61K9/06 ,  A61K31/194 ,  A61K31/375 ,  A61K9/50 ,  C01B21/24 ,  A61K33/22

CPC分类号： A61K33/00 ,  A01N59/14 ,  A61K9/06 ,  A61K9/14 ,  A61K9/50 ,  A61K9/5047 ,  A61K9/5052 ,  A61K9/70 ,  A61K31/19 ,  A61K31/194 ,  A61K31/341 ,  A61K31/375 ,  A61K33/22 ,  A61K45/06 ,  A61K47/36 ,  C01B21/24 ,  A61K2300/00

摘要： Methods and compositions are provided for generating and applying long-lasting therapeutic nitric oxide (NO) gas from the reaction of a least one microencapsulated nitrite salt and an activating volume of an aqueous acidified gel that has sufficient acidity to convert the nitrite salt to a nitric oxide (NO) and further provides a reducing property that retains the NO in bioactive form

摘要翻译： 提供的方法和组合物用于从至少一个微囊化亚硝酸盐和具有足够酸度以将亚硝酸盐转化为硝酸的酸性水凝胶的活化体积的反应产生和施用持久的治疗性一氧化氮（NO） 氧化物（NO），并且还提供将NO保持为生物活性形式的还原性质

公开(公告)号：US09526744B2

公开(公告)日：2016-12-27

申请号：US14302282

申请日：2014-06-11

申请人： Air Liquide Santé (International)

发明人： Pierre De Villemeur ,  Laurent Lecourt

IPC分类号： A61K33/00 ,  C01B21/24 ,  C01B21/04 ,  A61M16/12

CPC分类号： A61K33/00 ,  A61M16/107 ,  A61M16/12 ,  A61M2202/0266 ,  A61M2202/0275 ,  A61M2202/0283 ,  A61M2207/00 ,  C01B21/0422 ,  C01B21/0433 ,  C01B21/045 ,  C01B21/24 ,  C01B2210/0006 ,  C01B2210/001 ,  C01B2210/0045 ,  C01B2210/0062

摘要： The invention relates to a method for producing an NO/N2 gaseous mixture, comprising the steps of effecting a purification of impure gaseous nitrogen containing impurities at least of the O2 type by putting the impure nitrogen in contact with a catalyst and then with a molecular sieve; mixing the pure nitrogen obtained with nitric oxide (NO), and obtaining a mixture formed from NO and pure nitrogen containing an NO content of less than 20% by volume and a proportion of impurities of the O2 type of less than 5 ppmv and of the H2O type of less than 40 ppmv. The NO/nitrogen mixture may undergo supplementary dilutions with pure nitrogen. Such NO/nitrogen mixtures can be used for treating, by inhalation, pulmonary vasoconstrictions in adults or children, in particular in new-born babies suffering from primitive pulmonary hypertension or in patients undergoing heart surgery.

摘要翻译： 本发明涉及一种生产NO / N2气体混合物的方法，包括以下步骤：通过将不纯氮与催化剂接触，然后用分子筛来净化至少含有O 2型杂质的不纯气态氮 ; 将得到的纯氮与一氧化氮（NO）混合，得到由NO和NO含量低于20体积％，O 2类型的杂质的比例小于5ppmv的纯氮和 H2O类型小于40 ppmv。 NO /氮混合物可以用纯氮进行补充稀释。 这种NO /氮混合物可用于通过吸入治疗成人或儿童的肺血管收缩，特别是在患有原始肺动脉高压的新生婴儿或患有心脏手术的患者中。

公开(公告)号：US09493352B2

公开(公告)日：2016-11-15

申请号：US14192691

申请日：2014-02-27

申请人： Colorado State University Research Foundation

发明人： Melissa M. Reynolds ,  Benjamin P. Reynolds

IPC分类号： C01B21/26 ,  A61K33/00 ,  A61L27/54 ,  A61L29/16 ,  A61L31/16 ,  C01B21/24 ,  A61L29/06 ,  A61L31/06 ,  A61L29/14 ,  A61L31/14

CPC分类号： C01B21/265 ,  A61K33/00 ,  A61L27/54 ,  A61L29/06 ,  A61L29/146 ,  A61L29/16 ,  A61L31/06 ,  A61L31/146 ,  A61L31/16 ,  A61L2300/114 ,  A61L2300/608 ,  C01B21/24

摘要： The present disclosure is directed to a method of producing nitric oxide comprising (i) providing a composition comprising a metal-organic framework, and (ii) exposing the composition to a nitric oxide-releasing compound. The disclosure also is directed to compositions, coatings, and medical devices comprising a metal-organic framework.

摘要翻译： 本公开涉及一种生产一氧化氮的方法，其包括（i）提供包含金属 - 有机骨架的组合物，和（ii）将所述组合物暴露于释放一氧化氮的化合物。 本公开还涉及包含金属 - 有机骨架的组合物，涂层和医疗装置。