公开(公告)号：US09896659B2

公开(公告)日：2018-02-20

申请号：US14352410

申请日：2012-10-17

Applicant: STOWERS INSTITUTE FOR MEDICAL RESEARCH

Inventor： John M Perry ,  Linheng Li ,  Aparna Venkatraman ,  Xi He

IPC: C12N5/00 ,  C12N5/02 ,  C12N5/18 ,  C12N5/0789 ,  A61K35/28

CPC classification number: C12N5/0647 ,  A61K35/28 ,  C12N2501/06 ,  C12N2501/415

Abstract: Methods and kits for expanding a stem cell population, particularly a hematopoietic stem cell population, in the presence of a DNA methyltransferase modulator and a Wnt pathway modulator are disclosed.

公开(公告)号：US20140255359A1

公开(公告)日：2014-09-11

申请号：US14352410

申请日：2012-10-17

Applicant: STOWERS INSTITUTE FOR MEDICAL RESEARCH

Inventor： John M. Perry ,  Linheng Li ,  Aparna Venkatraman ,  Xi He

IPC: C12N5/0789 ,  A61K35/28

CPC classification number: C12N5/0647 ,  A61K35/28 ,  C12N2501/06 ,  C12N2501/415

Abstract: Methods and kits for expanding a stem cell population, particularly a hematopoietic stem cell population, in the presence of a DNA methyltransferase modulator and a Wnt pathway modulator are disclosed.

Abstract translation: 公开了在DNA甲基转移酶调节剂和Wnt途径调节剂存在下扩增干细胞群体，特别是造血干细胞群体的方法和试剂盒。