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7 条记录 (耗时 0.011 秒)

    Process for preparing 1-acyl-2-phenyl-3-indolylaliphatic acid derivatives
    2.
    发明授权
    Process for preparing 1-acyl-2-phenyl-3-indolylaliphatic acid derivatives 失效
    制备1-乙酰基-2-苯基-3-间苯二酚酸衍生物的方法

    公开(公告)号：US3564008A

    公开(公告)日：1971-02-16

    申请号：US3564008D

    申请日：1968-01-03

    申请人： SUMITOMO CHEMICAL CO

    发明人： YAMAMOTO HISAO ,  NAKAMURA YASUSHI ,  NAKAO MASARU ,  ATSUMI TOSHIO ,  KOBAYASHI TSUYOSHI

    IPC分类号： C07D209/26 ,  C07D27/56

    CPC分类号： C07D209/26

    摘要： A 1-ACYL-2-PHENYL-3-INDOYLALIPHATIC ACID DERIVATIVE REPRESENTED BY THE FORMULA,

    1-(R2-CO-),2-(R3-PHENYL),3-(R5-CO-CH(-R4)-),R1-INDOLE

    WHEREIN R1 IS A HYDROGEN ATOM, A LOWER ALKOXY GROUP, ETC.; R2 IS A HYDROGEN- OR LOWER ALKYL-SUBSTITUTED PHENYL GROUP, ETC.; R3 IS A HYDROGEN ATOM OR A LOWER ALKYL GROUP, ETC; R4 IS A HYDROGEN ATOM OR A LOWER ALKYL; AND R5 IS A HYDROXY GROUP, ETC., IS OBTAINED BY REACTING A CORRESPONDING N1-ACYL PHENYLHYDRAZINE DERIVATIVE OR A MINERAL ACID SALT THEREOF WITH A CORRESPONDING PHENYL KETONE COMPOUND. THE TYPICAL EXAMPLES THEREOF ARE 1-(P-CHLOROBENZOYL)2-PHENYL 5-METHOXY - 3 - INDOLYACETICA CID AND 1-(PMETHYLBENZOYL)-2-PHENYL - 5 - METHOXY - 3 - INDOLYLACETIC ACID. THE COMPOUNDS THUS OBTAINED HAVE REMARKABLE ANTIINFLAMMATORY, ANALGESIC AND ANTIPYRETIC ACTIONS.

    Substituted n-1,2-diphenylethyl fatty amides as cholesteremics
    6.
    发明授权
    Substituted n-1,2-diphenylethyl fatty amides as cholesteremics 失效
    取代的N-1,2-二苯甲基脂肪酸作为胆固醇

    公开(公告)号：US3597458A

    公开(公告)日：1971-08-03

    申请号：US3597458D

    申请日：1969-04-25

    申请人： SUMITOMO CHEMICAL CO

    发明人： NAKAMURA YASUSHI ,  KIMURA MICHIO ,  SUZUKI YOSHIO ,  HAMMA NORITAKA ,  FUKUMARU TOSHITSUGU ,  AONO SHUNJI ,  FUKUSHIMA HIDEAKI

    IPC分类号： C09F7/00

    摘要： YL)

    R-CO-NH-CH(-CH2-,R3-,R4-BENZENETRIYL)-(R1-,R2-BENZENETRI-

    NOVEL AMIDE COMPOUNDS HAVING ANTIATHEROSCLEROSIS ACTIONS WHICH ARE REPRESENTED BY THE FORMULA:
    WHEREIN R REPRESENTS A C15-C25, STRAIGHT, CHAIN OR BRANCHED-CHAIN, NATURAL OR SYNTHETIC SATURATED OR UNSATURATE ALIPHATIC GROUP HAVING OR NOT HAVING HYDROXYL GROUP; R1, R2, R3 AND R4 REPRESENT INDIVIDUALLY A HYDROGEN ATOM, A LOWER ALKYL GROUP, A LOWER ALKOXY GROUP OR A HALOGEN ATOM BUT CANNOT BE HYDROGEN ATOMS AT THE SAME TIME. THE ABOVE-MENTIONED AMIDE COMPOUNDS CAN BE USED AS DRUGS. THEY CAN BE USED BY ADDING THEM TO FOOD-STUFF ADDITIVES SUCH AS BUTTER AND THE LIKE FOR PREVENTING THE DEPOSITION OF CHOLESTEROL ONTO THE WALLS OF BLOOD VESSELS.