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    Certain thienyl aliphatic hydrocarbon amides
    1.
    发明授权
    Certain thienyl aliphatic hydrocarbon amides 失效
    某些乙烯二烃基碳酰胺

    公开(公告)号：US3666774A

    公开(公告)日：1972-05-30

    申请号：US3666774D

    申请日：1969-08-29

    申请人： SUMITOMO CHEMICAL CO

    发明人： SUZUKI YOSHIO ,  AONO SHUNJI ,  FUKUSHIMA HIDEAKI

    IPC分类号： C07D213/30 ,  C07D307/52 ,  C07D333/20 ,  C07D63/10

    CPC分类号： C07D213/30 ,  C07D307/52 ,  C07D333/20 ,  Y10S514/824

    摘要： A novel fatty acid amide useful as an anti-arteriosclerotic agent which is represented by the formula, WHEREIN R represents a saturated or unsaturated straight or branched aliphatic hydrocarbon group having 15 to 25 carbon atoms which may bear a hydroxyl group, A represents a lower alkyl group, aryl group or aralkyl group and B represents a heterocyclic radical containing a nitrogen, oxygen or sulfur atom, such as, for example, Alpha -(thienyl or pyridyl)-ethyl or benzyl amide of linoleic acid, isostearic acid, linolenic acid, oleic acid or safflower oil. These compounds are prepared by reacting the appropriate fatty acid or reactive derivative with an amine of the formula, These compounds may be incorporated in foodstuffs or ingested with a suitable carrier.

    摘要翻译： 一种用作抗动脉硬化剂的新型脂肪酸酰胺，其由下式表示：WHEREIN R表示可具有羟基的饱和或不饱和的具有15至25个碳原子的直链或支链脂族烃基，A表示低级烷基 基团，芳基或芳烷基，B表示含有氮，氧或硫原子的杂环基，例如亚油酸的α-（噻吩基或吡啶基） - 乙基或苄基酰胺，异硬脂酸，亚麻酸 酸，油酸或红花油。 这些化合物可以通过使适当的脂肪酸或活性衍生物与下式的胺反应来制备。这些化合物可以掺入食品中或用合适的载体摄取。

    Substituted n-1,2-diphenylethyl fatty amides as cholesteremics
    4.
    发明授权
    Substituted n-1,2-diphenylethyl fatty amides as cholesteremics 失效
    取代的N-1,2-二苯甲基脂肪酸作为胆固醇

    公开(公告)号：US3597458A

    公开(公告)日：1971-08-03

    申请号：US3597458D

    申请日：1969-04-25

    申请人： SUMITOMO CHEMICAL CO

    发明人： NAKAMURA YASUSHI ,  KIMURA MICHIO ,  SUZUKI YOSHIO ,  HAMMA NORITAKA ,  FUKUMARU TOSHITSUGU ,  AONO SHUNJI ,  FUKUSHIMA HIDEAKI

    IPC分类号： C09F7/00

    摘要： YL)

    R-CO-NH-CH(-CH2-,R3-,R4-BENZENETRIYL)-(R1-,R2-BENZENETRI-

    NOVEL AMIDE COMPOUNDS HAVING ANTIATHEROSCLEROSIS ACTIONS WHICH ARE REPRESENTED BY THE FORMULA:
    WHEREIN R REPRESENTS A C15-C25, STRAIGHT, CHAIN OR BRANCHED-CHAIN, NATURAL OR SYNTHETIC SATURATED OR UNSATURATE ALIPHATIC GROUP HAVING OR NOT HAVING HYDROXYL GROUP; R1, R2, R3 AND R4 REPRESENT INDIVIDUALLY A HYDROGEN ATOM, A LOWER ALKYL GROUP, A LOWER ALKOXY GROUP OR A HALOGEN ATOM BUT CANNOT BE HYDROGEN ATOMS AT THE SAME TIME. THE ABOVE-MENTIONED AMIDE COMPOUNDS CAN BE USED AS DRUGS. THEY CAN BE USED BY ADDING THEM TO FOOD-STUFF ADDITIVES SUCH AS BUTTER AND THE LIKE FOR PREVENTING THE DEPOSITION OF CHOLESTEROL ONTO THE WALLS OF BLOOD VESSELS.