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    Esters of 3-pyrozolemethanols and process for their preparations
    1.
    发明授权
    Esters of 3-pyrozolemethanols and process for their preparations 失效
    3-吡咯烷酮的酯及其制备方法

    公开(公告)号：US3666756A

    公开(公告)日：1972-05-30

    申请号：US3666756D

    申请日：1969-06-16

    申请人： SUMITOMO CHEMICAL CO

    发明人： FUKUMURA MASATAKA ,  SHIMAGO KOZO ,  OKANO SHIGERU ,  NAKATANI HIROSHI ,  HESAKA KENJI

    IPC分类号： C07D231/12 ,  C07D49/18

    CPC分类号： C07D231/12 ,  Y10S514/866

    摘要： Novel pyrazole derivatives represented by the formula: WHEREIN R1 represents an alkyl group, alkenyl group, aryl group, aryloxyalkyl group, aralkyl group, aralkenyl group, or a group containing a heterocyclic ring, and R2 is a hydrogen atom or the same group as -CO-R1. The pyrazole derivatives have a good antidiabetic action, and are prepared by diacylating 3hydroxymethyl-5-methylpyrazole with an acylating agent represented by the general formula, X-CO-R1, wherein X represents a halogen atom, a group of -O-CO-R1 or a group of -O-CO-O-R3, R1 has the same meaning as defined above, and R3 represents an alkyl group having one to four carbon atoms, and, if necessary, by subjecting the thus obtained diacylated pyrazole derivatives to partial hydrolysis or aminolysis.

    摘要翻译： 由下式表示的新型吡唑衍生物：