公开(公告)号：US20200205445A1

公开(公告)日：2020-07-02

申请号：US16815212

申请日：2020-03-11

Applicant: SYMRISE AG

Inventor： Katharina REICHELT ,  Jakob Peter Ley ,  Petra Hoffmann-Lücke ,  Maria Blings ,  Susanne Paetz ,  Thomas Riess

IPC: A23L2/60 ,  A23L27/60 ,  A23L7/10 ,  A23L27/30 ,  A23G3/36 ,  A23G4/06 ,  A23G9/32 ,  A61K36/185 ,  A23G9/42 ,  A23G1/48 ,  A23G3/48 ,  A23G1/32

Abstract: A flavoring mixture, comprising (i) one or more sweet-tasting substances, selected from the group of naturally occurring sweet-tasting substances and the physiologically compatible salts thereof without phyllodulcin and the physiologically compatible salts thereof, and (ii) phyllodulcin and/or one or more of the physiologically compatible salts thereof, wherein the ratio of the sucrose equivalence of the concentration of the substance or substances of group (i) to the sucrose equivalence of the concentration of the substance or substances of group (i) is ≥2.

公开(公告)号：US20130251730A1

公开(公告)日：2013-09-26

申请号：US13782391

申请日：2013-03-01

Applicant: SYMRISE AG

Inventor： Jakob Ley ,  Katharina Reichelt ,  Marcus Götz ,  Maria Blings ,  Veronika Somoza ,  Jessica Walker ,  Joel Michael Walker

IPC: A61K31/192 ,  C07D311/58 ,  A23L1/30 ,  C07D311/32 ,  A61K45/06 ,  C07C65/40 ,  A61K31/353

CPC classification number: A61K31/192 ,  A23L33/105 ,  A61K8/365 ,  A61K8/498 ,  A61K31/352 ,  A61K31/353 ,  A61K45/06 ,  A61K2800/10 ,  A61Q19/00 ,  C07C65/40 ,  C07D311/32 ,  C07D311/58 ,  A61K2300/00

Abstract: Suggested is a compound of the formula (X) or any salt of a compound of the formula (X) or any mixture containing or consisting of two or more different compounds of the formula (X), two or more different salts of compounds of the formula (X) or one or more different compounds of the formula (X) and one or more different salts of compounds of the formula (X), wherein for R1, R2 and R3 independently of one another in every compound of the formula (X) the following applies: R1 means hydrogen or methyl, R2 means an organic residue with 5 carbon atoms and one oxygen atom or none and R3 means an organic residue with 10 carbon atoms and one or more oxygen atoms, or R1 and R2 together with the carbon atoms in positions 4 and 5 and the oxygen atom bound to the carbon atom in position 4 form a ring and comprise 5 carbon atoms and one oxygen atom or none, and R3 means an organic residue with 10 carbon atoms and one or more oxygen atoms, for use in a method for the prophylaxis and/or treatment of inflammation.

Abstract translation: 建议式（X）的化合物或式（X）化合物的任何盐或含有两种或更多种不同式（X）化合物的任何混合物或两种或更多种不同的 式（X）或一种或多种不同的式（X）化合物和一种或多种式（X）化合物的不同盐，其中对于R 1，R 2和R 3在每个式（X ）适用：R 1表示氢或甲基，R 2表示具有5个碳原子和一个氧原子的有机残基或不表示R 3表示具有10个碳原子和一个或多个氧原子的有机残基，或R 1和R 2与 位置4和5中的碳原子和结合到位置4的碳原子的氧原子形成环，并且包含5个碳原子和一个氧原子或不存在，并且R 3表示具有10个碳原子和一个或多个氧原子的有机残基 ，用于预防和/或治疗的方法 炎症。

公开(公告)号：US08906958B2

公开(公告)日：2014-12-09

申请号：US13779046

申请日：2013-02-27

Applicant: Symrise AG

Inventor： Katharina Reichelt ,  Jakob Ley ,  Marcus Götz ,  Maria Blings

IPC: A61K31/352 ,  A61K31/192 ,  A61K45/06 ,  C07D311/58 ,  C07C65/40 ,  A61K31/353 ,  A23L1/30 ,  C07D311/32

CPC classification number: A61K31/192 ,  A23L33/105 ,  A61K8/365 ,  A61K8/498 ,  A61K31/352 ,  A61K31/353 ,  A61K45/06 ,  A61K2800/10 ,  A61Q19/00 ,  C07C65/40 ,  C07D311/32 ,  C07D311/58 ,  A61K2300/00

Abstract: The invention relates to certain compounds, salts of these compounds and mixtures containing or consisting of two or more such compounds, two or more such salts or one or more such compounds and one or more such salts, each for use in a method for the prophylaxis and/or treatment of inflammation, in particular of inflammation of the skin.

Abstract translation: 本发明涉及某些化合物，这些化合物的盐和含有两种或更多种这样的化合物或两种或更多种这样的化合物或其组合的混合物，一种或多种这样的化合物和一种或多种这样的盐，各自用于预防方法 和/或治疗炎症，特别是皮肤炎症。

公开(公告)号：US20130236472A1

公开(公告)日：2013-09-12

申请号：US13779046

申请日：2013-02-27

Applicant: SYMRISE AG

Inventor： Katharina Reichelt ,  Jakob Ley ,  Marcus Götz ,  Maria Blings

IPC: C07C65/40 ,  A61K45/06 ,  A61K31/352 ,  C07D311/58 ,  A61K31/192

CPC classification number: A61K31/192 ,  A23L33/105 ,  A61K8/365 ,  A61K8/498 ,  A61K31/352 ,  A61K31/353 ,  A61K45/06 ,  A61K2800/10 ,  A61Q19/00 ,  C07C65/40 ,  C07D311/32 ,  C07D311/58 ,  A61K2300/00

Abstract: The invention relates to certain compounds, salts of these compounds and mixtures containing or consisting of two or more such compounds, two or more such salts or one or more such compounds and one or more such salts, each for use in a method for the prophylaxis and/or treatment of inflammation, in particular of inflammation of the skin.

Abstract translation: 本发明涉及某些化合物，这些化合物的盐和含有两种或更多种这样的化合物或两种或更多种这样的化合物或其组合的混合物，一种或多种这样的化合物和一种或多种这样的盐，各自用于预防方法 和/或治疗炎症，特别是皮肤炎症。