公开(公告)号：US20190178782A1

公开(公告)日：2019-06-13

申请号：US16211469

申请日：2018-12-06

Applicant: SYSMEX CORPORATION

Inventor： Takanori MAEKAWA ,  Yusuke KONISHI

IPC: G01N15/14 ,  C12Q1/6806 ,  C12Q1/6883 ,  C12Q1/686 ,  G01N33/569 ,  G01N33/58 ,  C12Q1/689 ,  C12Q1/6841

Abstract: A particle measuring method, a sample processing method, and a particle imaging apparatus capable of efficiently acquiring information effective in pathological diagnosis or the like are provided. The particle measuring method comprises a step (S13) of labeling and amplifying, within a particle, a target nucleic acid in the particle, a step (S14) of labeling a surface target polypeptide on the surface of the particle and/or target nucleic acid different from the first target nucleic acid, and a step (S2) of measuring the labeled target nucleic acid and the labeled target polypeptide and/or other labeled target nucleic acid.

公开(公告)号：US20190049379A1

公开(公告)日：2019-02-14

申请号：US16059340

申请日：2018-08-09

Applicant: SYSMEX CORPORATION

Inventor： Yusuke KONISHI ,  Kazuhiro YAMADA ,  Shohei MATSUMOTO

IPC: G01N21/64 ,  G01J3/28 ,  C12Q1/6809

Abstract: Disclosed is a sample analyzer that includes: a measurement unit configured to apply light to a measurement specimen containing a plurality of kinds of target substances each labeled with fluorescence, and detect a plurality of kinds of fluorescences having different wavelengths; and a processing unit configured to analyze the plurality of kinds of target substances based on a detection result from the measurement unit, and information, on a color of fluorescence, which is set to be variable so as to correspond to the plurality of kinds of target substances.

公开(公告)号：US20180299382A1

公开(公告)日：2018-10-18

申请号：US15951562

申请日：2018-04-12

Applicant: SYSMEX CORPORATION

Inventor： Kazuhiro YAMADA ,  Shohei MATSUMOTO ,  Yusuke KONISHI

IPC: G01N21/64

Abstract: Disclosed is a fluorescence image analyzing apparatus including a light source that emits light to a sample including a plurality of cells labeled with a fluorescent dye at a target site, an imaging unit that captures a fluorescence image of each of the cells that emit fluorescence by being irradiated with the light, a fluorescence image of the cell, and a processing unit that processes the fluorescence image captured by the imaging unit to acquire a bright spot pattern of fluorescence in the fluorescence image. The processing unit selects a reference pattern corresponding to a measurement item of the sample from a plurality of reference patterns corresponding to a plurality of measurement items and generates information used for determination of the sample based on the bright spot pattern of fluorescence in the fluorescence image and the selected reference pattern.

公开(公告)号：US20140295488A1

公开(公告)日：2014-10-02

申请号：US14227795

申请日：2014-03-27

Applicant: SYSMEX CORPORATION

Inventor： Yusuke KONISHI ,  Yasuyuki KAWASHIMA ,  Kazuhiro YAMADA ,  Keiko YOSHIKAWA

IPC: G01N21/49

CPC classification number: G01N21/49 ,  G01N15/0205 ,  G01N15/1434 ,  G01N33/56972 ,  G01N2015/1402

Abstract: A blood cell analyzer comprising a flow cell configured to flow a measurement specimen containing blood cells, a first light source configured to emit light having a first wavelength, a second light source configured to emit light having a second wavelength different from the first wavelength, a first light receiving portion configured to receive first scattered light generated by irradiating the blood cells in the measurement specimen with light from the first light source, a second light receiving portion configured to receive second scattered light generated by irradiating the blood cells in the measurement specimen with light from the second light source, and a control section configured to classify at least white blood cells from the blood cells contained in the measurement specimen, based on a detection signal output from the first light receiving portion and a detection signal output from the second light receiving portion.

Abstract translation: 1.一种血细胞分析装置，其特征在于，包括流动池，其构造成使含有血细胞的测定试样流动，配置成发射具有第一波长的光的第一光源，被配置为发射具有与所述第一波长不同的第二波长的光的第二光源， 第一受光部，被配置为接收通过用来自第一光源的光照射测量样本中的血细胞而产生的第一散射光;第二光接收部，被配置为接收通过用测量样本中的血细胞照射而产生的第二散射光， 来自第二光源的光，以及控制部，被配置为基于从第一光接收部输出的检测信号和从第二光输出的检测信号，对包含在测量样本中的血细胞中的至少白细胞进行分类 接收部分。