公开(公告)号：US08241573B2

公开(公告)日：2012-08-14

申请号：US12295337

申请日：2007-03-30

申请人： Saibal Banerjee ,  Colin Barnes ,  Kevin Benson ,  Jason Bryant ,  Dale Buermann ,  Sergey Etchin ,  Johnny Ho ,  Xavier Lee ,  Peter Lundberg ,  Klaus Maisinger ,  Bojan Obradovic ,  Mark Pratt ,  Mark Reed ,  Chiara Rodighiero ,  Subra Sankar ,  Harold Swerdlow ,  Eric Vermaas

发明人： Saibal Banerjee ,  Colin Barnes ,  Kevin Benson ,  Jason Bryant ,  Dale Buermann ,  Sergey Etchin ,  Johnny Ho ,  Xavier Lee ,  Peter Lundberg ,  Klaus Maisinger ,  Bojan Obradovic ,  Mark Pratt ,  Mark Reed ,  Chiara Rodighiero ,  Subra Sankar ,  Harold Swerdlow ,  Eric Vermaas

IPC分类号： G01N21/64 ,  G06K9/00 ,  C12M1/36

CPC分类号： C12Q1/6869 ,  C12Q2535/122 ,  C12Q2565/60 ,  G01N21/6456

摘要： The present invention comprises systems and devices for sequencing of nucleic acid, such as short DNA sequences from clonally amplified single-molecule arrays.

摘要翻译： 本发明包括用于核酸测序的系统和装置，例如来自克隆扩增的单分子阵列的短DNA序列。

公开(公告)号：US20110108724A1

公开(公告)日：2011-05-12

申请号：US12967451

申请日：2010-12-14

申请人： Kenneth J. Ewing ,  Danielle N. Dickinson ,  Douglas B. Henderson ,  Johnny Ho

发明人： Kenneth J. Ewing ,  Danielle N. Dickinson ,  Douglas B. Henderson ,  Johnny Ho

IPC分类号： H01J49/00

CPC分类号： G01N1/405 ,  B01D53/0415 ,  B01D2253/102 ,  B01D2253/202 ,  B01D2253/204 ,  B01D2258/0225 ,  B01D2259/4583 ,  G01N1/2214 ,  G01N2001/022 ,  H01J49/0409

摘要： A chemical sample collection and detection system is disclosed. The chemical sample collection and detection system includes a sample collection device and a detection device. The sample collection device includes a housing having two opposite sides and at least one openings on each side to allow a fluid sample passing through the housing; and a sorbent material placed between the two opposite sides of the housing or a sorbent coated screen. The sorbent material adsorbs chemical vapors, and traps particles and aerosols in the fluid sample when the fluid sample passes the housing through the openings. The detection device includes an atmospheric pressure ionization source and an ion detector. The atmospheric pressure ionization source desorbs and ionizes the chemicals trapped/sorbed on the sorbent material and the ion detector analyzes the ions for the presence of the sorbed chemical.

摘要翻译： 公开了一种化学样品收集和检测系统。 化学样品收集和检测系统包括样品收集装置和检测装置。 样品收集装置包括具有两个相对侧的壳体和每侧上的至少一个开口，以允许流体样品​​通过壳体; 以及放置在壳体的两个相对侧或吸附剂涂覆的屏幕之间的吸附剂材料。 当流体样品通过开口通过壳体时，吸附剂材料吸附化学蒸气并捕获流体样品中的颗粒和气溶胶。 检测装置包括大气压电离源和离子检测器。 大气压离子源解吸并吸附在吸附剂材料上捕获/吸附的化学物质，离子检测器分析离子以吸附吸附剂的存在。

公开(公告)号：US20100096546A1

公开(公告)日：2010-04-22

申请号：US12643801

申请日：2009-12-21

申请人： Kenneth J. Ewing ,  Danielle N. Dickinson ,  Douglas B. Henderson ,  Johnny Ho ,  Robert Milloy

发明人： Kenneth J. Ewing ,  Danielle N. Dickinson ,  Douglas B. Henderson ,  Johnny Ho ,  Robert Milloy

IPC分类号： B01D59/44 ,  H01J49/00

CPC分类号： H01J49/0431

摘要： A chemical detection system is disclosed. The chemical detection system includes an atmospheric pressure ionization (API) source that produces an API stream, a sample delivery system that delivers a liquid sample in a continuous manner to the API stream, an ion detector capable of detecting a molecule of interest and a control device. Also disclosed is a method for detecting a chemical of interest in a liquid sample.

摘要翻译： 公开了一种化学检测系统。 化学检测系统包括产生API流的大气压电离源（API）源，以API连续方式将液体样品输送到API流的样品递送系统，能够检测感兴趣分子和控制的离子检测器 设备。 还公开了一种用于检测液体样品中感兴趣的化学物质的方法。

公开(公告)号：US20090317916A1

公开(公告)日：2009-12-24

申请号：US12213694

申请日：2008-06-23

申请人： Kenneth J. Ewing ,  Danielle N. Dickinson ,  Douglas B. Henderson ,  Johnny Ho

发明人： Kenneth J. Ewing ,  Danielle N. Dickinson ,  Douglas B. Henderson ,  Johnny Ho

IPC分类号： G01N30/96

CPC分类号： G01N1/405 ,  B01D53/0415 ,  B01D2253/102 ,  B01D2253/202 ,  B01D2253/204 ,  B01D2258/0225 ,  B01D2259/4583 ,  G01N1/2214 ,  G01N2001/022 ,  H01J49/0409

摘要： A chemical sample collection and detection system is disclosed. The chemical sample collection and detection system includes a sample collection device and a detection device. The sample collection device includes a housing having two opposite sides and at least one openings on each side to allow a fluid sample passing through the housing; and a sorbent material placed between the two opposite sides of the housing or a sorbent coated screen. The sorbent material adsorbs chemical vapors, and traps particles and aerosols in the fluid sample when the fluid sample passes the housing through the openings. The detection device includes an atmospheric pressure ionization source and an ion detector. The atmospheric pressure ionization source desorbs and ionizes the chemicals trapped/sorbed on the sorbent material and the ion detector analyzes the ions for the presence of the sorbed chemical.

摘要翻译： 公开了一种化学样品收集和检测系统。 化学样品收集和检测系统包括样品收集装置和检测装置。 样品收集装置包括具有两个相对侧的壳体和每侧上的至少一个开口，以允许流体样品​​通过壳体; 以及放置在壳体的两个相对侧或吸附剂涂覆的屏幕之间的吸附剂材料。 当流体样品通过开口通过壳体时，吸附剂材料吸附化学蒸气并捕获流体样品中的颗粒和气溶胶。 检测装置包括大气压电离源和离子检测器。 大气压离子源解吸并吸附在吸附剂材料上捕获/吸附的化学物质，离子检测器分析离子以吸附吸附剂的存在。