公开(公告)号：US20140113384A1

公开(公告)日：2014-04-24

申请号：US13658614

申请日：2012-10-23

Applicant: Sam KAVUSI ,  Frederik Kotz

Inventor： Sam KAVUSI ,  Frederik Kotz

IPC: G01N33/53

CPC classification number: G01N33/561 ,  G01N33/54366

Abstract: Lateral flow immunoassay devices for determining the concentration of an analyte in a sample and methods for measuring analyte concentration in sample using such lateral flow immunoassay devices.

Abstract translation: 用于确定样品中分析物浓度的侧流免疫测定装置和使用这种侧流免疫测定装置测量样品中分析物浓度的方法。

公开(公告)号：US20140274760A1

公开(公告)日：2014-09-18

申请号：US13834126

申请日：2013-03-15

Applicant: Nadezda FOMINA ,  Christopher JOHNSON ,  Sam KAVUSI ,  Habib AHMAD

Inventor： Nadezda FOMINA ,  Christopher JOHNSON ,  Sam KAVUSI ,  Habib AHMAD

IPC: G01N33/543

CPC classification number: G01N33/5438 ,  G01N27/3272

Abstract: Device for use in a biosensor comprising a multisite array of test sites, the device being useful for modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest from a biological by modulating the pH or ionic gradient near the electrodes in such biosensor. The device provides a biosensor which is more accurate, reliable and the results of which are more reproducible. Analytic methods for more accurately measuring an analyte of interest in a biological sample are also provided.

Abstract translation: 用于生物传感器的装置，其包括测试位点的多位阵列，所述装置可用于通过调节电极附近的pH或离子梯度来调节生物学上的（生物分子）探针或检测剂和目标分析物之间的结合相互作用 在这样的生物传感器。 该装置提供了更准确，可靠的生物传感器，其结果更加可重现。 还提供了用于更精确地测量生物样品中感兴趣的分析物的分析方法。

公开(公告)号：US20140274754A1

公开(公告)日：2014-09-18

申请号：US13800328

申请日：2013-03-13

Applicant: Christopher JOHNSON ,  Sam KAVUSI ,  Habib AHMAD ,  Christoph LANG

Inventor： Christopher JOHNSON ,  Sam KAVUSI ,  Habib AHMAD ,  Christoph LANG

IPC: G01N27/327

CPC classification number: G01N27/3276 ,  B01L3/5027 ,  B01L2300/0636 ,  B01L2300/0645 ,  B01L2300/069 ,  B01L2300/089 ,  B01L2400/0406 ,  G01N33/5438 ,  G01N33/558

Abstract: Lateral flow assay devices for determining the concentration of a biomolecular analyte in a sample and methods for measuring analyte concentration in sample using such lateral flow assay devices.

Abstract translation: 用于确定样品中生物分子分析物的浓度的侧流测定装置和使用这种侧流测定装置测量样品中的分析物浓度的方法。

公开(公告)号：US20140008244A1

公开(公告)日：2014-01-09

申请号：US13543300

申请日：2012-07-06

Applicant: Sam KAVUSI ,  Rajan Gangadharan ,  Christopher Johnson ,  Aldrich N. K. Lau ,  Piyush Verma

Inventor： Sam KAVUSI ,  Rajan Gangadharan ,  Christopher Johnson ,  Aldrich N. K. Lau ,  Piyush Verma

IPC: G01N27/26 ,  B82Y99/00

CPC classification number: G01N33/50 ,  G01N27/3275 ,  G01N33/5306

Abstract: Methods of modulating the binding interactions between a (biomolecular) probe or detection agent and an analyte of interest from a biological sample in a biosensor having a multisite array of test sites. In particular, the methods modulate the pH or ionic concentration gradient near the electrodes in such biosensor. The methods of modulating the binding interactions provide a biosensor and analytic methods for more accurately measuring an analyte of interest in a biological sample.

Abstract translation: 在生物传感器中调节生物样品中生物分子探针或检测剂与目的分析物之间的结合相互作用的方法，该生物传感器具有多个测试位点阵列。 特别地，该方法调节这种生物传感器中电极附近的pH或离子浓度梯度。 调节结合相互作用的方法提供了生物传感器和分析方法，用于更精确地测量生物样品中感兴趣的分析物。