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公开(公告)号：US20150197542A1
公开(公告)日：2015-07-16
申请号：US14595027
申请日：2015-01-12
Applicant: Samsung Electronics Co., Ltd.
Inventor： Donguk Kim , Geun Woong Kim , In Hwan Lim
CPC classification number: C07K16/2863 , C07K1/36 , C07K2317/24 , C07K2317/565 , C07K2317/567
Abstract: A method of purifying a protein from a protein-containing sample, a method of purifying an anti-c-Met antibody from a anti-c-Met containing sample, and an anti-c-Met antibody agent purified by such a method are provided.
Abstract translation: 提供了从含有蛋白质的样品中提纯蛋白质的方法，从含有抗c-Met的样品中纯化抗c-Met抗体的方法和通过该方法纯化的抗c-Met抗体试剂 。
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公开(公告)号：US09975960B2
公开(公告)日：2018-05-22
申请号：US14709214
申请日：2015-05-11
Applicant: Samsung Electronics Co., Ltd.
Inventor： Mi Young Cho , Powei Lin , Kwang Ho Cheong , Jae Woong Hwang , Geun Woong Kim , Han Na Choi
CPC classification number: C07K16/32 , A61K39/395 , A61K39/39533 , A61K39/39558 , A61K2039/507 , C07K16/2863 , C07K16/40 , C07K2317/24 , C07K2317/31 , C07K2317/34 , C07K2317/52 , C07K2317/56 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/77 , C07K2317/92
Abstract: An anti-HER2 antibody, an anti-c-Met/anti-HER2 bispecific antibody including the same, method for preparing same, and a method of preventing and/or treating a cancer using the same are provided.
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Patent Agency Ranking
公开(公告)号：US09517266B2
公开(公告)日：2016-12-13
申请号：US14231580
申请日：2014-03-31
Applicant: Samsung Electronics Co., Ltd.
Inventor： In Hwan Lim , Dong Uk Kim , Geun Woong Kim , Hee Kyung Sung , Yun Ju Jeong
CPC classification number: A61K39/39591 , A61K9/0019 , A61K9/08 , A61K47/183 , A61K47/26 , C07K16/2863 , C07K2317/14 , C07K2317/24 , C07K2317/52 , C07K2317/53 , C07K2317/565 , C07K2317/92
Abstract: Disclosed is a method of preparing a stabilized liquid formulation of a protein drug, comprising admixing a protein drug with a composition for stabilization, wherein the composition for stabilization comprises a surfactant, a buffer, and a liquid medium, and has a pH from about 5 to about 8.
Abstract translation: 公开了一种制备蛋白质药物的稳定化液体制剂的方法，其包括将蛋白质药物与用于稳定化的组合物混合，其中用于稳定化的组合物包含表面活性剂，缓冲剂和液体培养基，并且具有约5 至约8。
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公开(公告)号：US20150140014A1
公开(公告)日：2015-05-21
申请号：US14081886
申请日：2013-11-15
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seung Hyun LEE , Geun Woong Kim , Kyung Ah Kim , Hye Won Park , Ho Yeong Song , Young Mi Oh , Saet Byoul Lee , Ji Min Lee , Kwang Ho Cheong , Yun Ju Jeong , Mi Young Cho , Jae Hyun Choi , Yun Jeong Song , Yoon Aa Choi
IPC: C07K14/71 , A61K31/437 , A61K31/44 , A61K39/395 , A61K31/517
CPC classification number: A61K31/437 , A61K31/44 , A61K31/517 , A61K39/3955 , A61K39/39558 , C07K16/2863 , C07K2317/24 , C07K2317/53 , C07K2317/565 , C07K2317/622 , C07K2317/92 , C07K2319/30 , C12N5/163 , A61K2300/00
Abstract: A method for prevention or treatment of a cancer, comprising co-administering (a) an anti-c-Met antibody or an antigen-binding fragment thereof, and (b) at least one of lapatinib, regorafenib, vemurafenib or a combination thereof, to a subject in need thereof, and a pharmaceutical composition comprising (a) an anti-c-Met antibody or an antigen-binding fragment thereof, and (b) at least one of lapatinib, regorafenib, vemurafenib, or a combination thereof are provided.
Abstract translation: 一种预防或治疗癌症的方法，包括共同给予（a）抗c-Met抗体或其抗原结合片段，和（b）拉帕替尼，替罗非尼，伏马拉净或其组合中的至少一种， （a）抗c-Met抗体或其抗原结合片段，和（b）拉帕替尼，替罗非尼，伏马拉净或其组合中的至少一种提供给药物组合物 。
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公开(公告)号：US20140303357A1
公开(公告)日：2014-10-09
申请号：US14231580
申请日：2014-03-31
Applicant: Samsung Electronics Co., Ltd.
Inventor： In Hwan LIM , Dong Uk Kim , Geun Woong Kim , Hee Kyung Sung , Yun Ju Jeong
IPC: A61K39/395
CPC classification number: A61K39/39591 , A61K9/0019 , A61K9/08 , A61K47/183 , A61K47/26 , C07K16/2863 , C07K2317/14 , C07K2317/24 , C07K2317/52 , C07K2317/53 , C07K2317/565 , C07K2317/92
Abstract: Disclosed is a method of preparing a stabilized liquid formulation of a protein drug, comprising admixing a protein drug with a composition for stabilization, wherein the composition for stabilization comprises a surfactant, a buffer, and a liquid medium, and has a pH from about 5 to about 8.
Abstract translation: 公开了一种制备蛋白质药物的稳定化液体制剂的方法，其包括将蛋白质药物与用于稳定化的组合物混合，其中用于稳定化的组合物包含表面活性剂，缓冲剂和液体培养基，并且具有约5 至约8。
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公开(公告)号：US09717715B2
公开(公告)日：2017-08-01
申请号：US14081886
申请日：2013-11-15
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seung Hyun Lee , Geun Woong Kim , Kyung Ah Kim , Hye Won Park , Ho Yeong Song , Young Mi Oh , Saet Byoul Lee , Ji Min Lee , Kwang Ho Cheong , Yun Ju Jeong , Mi Young Cho , Jae Hyun Choi , Yun Jeong Song , Yoon Aa Choi
IPC: A61K39/395 , A61K31/437 , A61K31/517 , A61K31/44 , C07K16/28 , C12N5/16
CPC classification number: A61K31/437 , A61K31/44 , A61K31/517 , A61K39/3955 , A61K39/39558 , C07K16/2863 , C07K2317/24 , C07K2317/53 , C07K2317/565 , C07K2317/622 , C07K2317/92 , C07K2319/30 , C12N5/163 , A61K2300/00
Abstract: A method for prevention or treatment of a cancer, comprising co-administering (a) an anti-c-Met antibody or an antigen-binding fragment thereof, and (b) at least one of lapatinib, regorafenib, vemurafenib or a combination thereof, to a subject in need thereof, and a pharmaceutical composition comprising (a) an anti-c-Met antibody or an antigen-binding fragment thereof, and (b) at least one of lapatinib, regorafenib, vemurafenib, or a combination thereof are provided.
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公开(公告)号：US20140154251A1
公开(公告)日：2014-06-05
申请号：US14081917
申请日：2013-11-15
Applicant: Samsung Electronics Co., Ltd.
Inventor： Seung Hyun LEE , Geun Woong Kim , Kyung Ah Kim , Hye Won Park , Ho Yeong Song , Young Mi Oh , Saet Byoul Lee , Ji Min Lee , Kwang Ho Cheong , Yun Ju Jeong , Mi Young Cho , Jae Hyun Choi , Yun Jeong Song , Yoon Aa Choi
IPC: C07K16/28
CPC classification number: C07K16/2863 , A61K2039/505 , C07K2317/24 , C07K2317/52 , C07K2317/53 , C07K2317/565 , C07K2317/622 , C07K2317/73 , C07K2317/92
Abstract: An anti-c-Met antibody or antibody fragment and pharmaceutical composition comprising same, as well as a method for preventing and treating cancer by administering the antibody to a subject are provided.
Abstract translation: 提供了抗c-Met抗体或抗体片段及包含其的药物组合物，以及通过向受试者施用抗体来预防和治疗癌症的方法。
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