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公开(公告)号:US20050221455A1
公开(公告)日:2005-10-06
申请号:US10969245
申请日:2004-10-21
申请人: Sara McFarlan , Paula Hicks , Mary Zidwick , Fernando Sanchez-Riera , Douglas Cameron , Mervyn deSouza , John Rosazza , Steven Gort , Timothy Abraham
发明人: Sara McFarlan , Paula Hicks , Mary Zidwick , Fernando Sanchez-Riera , Douglas Cameron , Mervyn deSouza , John Rosazza , Steven Gort , Timothy Abraham
CPC分类号: C12N9/88 , C12P17/10 , Y02P20/582
摘要: Methods and compositions that can be used to make monatin or salt thereof from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid, are provided. Methods are also disclosed for producing the indole-3-pyruvate and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid intermediates. Compositions provided include nucleic acid molecules, polypeptides, chemical structures, and cells. Methods include in vitro and in vivo processes, and the in vitro methods include chemical reactions.
摘要翻译: 可用于从葡萄糖,色氨酸,吲哚-3-乳酸,吲哚-3-丙酮酸和2-羟基2-(吲哚-3-基甲基)-4-酮戊二酸制备莫纳甜或其盐的方法和组合物 ,提供。 还公开了制备吲哚-3-丙酮酸和2-羟基2-(吲哚-3-基甲基)-4-酮戊二酸中间体的方法。 提供的组合物包括核酸分子,多肽,化学结构和细胞。 方法包括体外和体内过程,体外方法包括化学反应。