公开(公告)号：US5017483A

公开(公告)日：1991-05-21

申请号：US13797

申请日：1987-02-12

申请人： Satoru Furukawa ,  Akio Ozaki ,  Toshihide Nakanishi ,  Yukinobu Kotani ,  Masahiro Sugimoto

发明人： Satoru Furukawa ,  Akio Ozaki ,  Toshihide Nakanishi ,  Yukinobu Kotani ,  Masahiro Sugimoto

IPC分类号： C12P13/08

CPC分类号： C12R1/19 ,  C12P13/08 ,  Y10S435/849

摘要： A process is disclosed for producing L-threonine, the process involves culturing in a medium a microorganism of the genus Escherichia capable of producing L-threonine which has resistance to at least one of rifampicin, lysine, methionine, aspartic acid and homoserine, or a decreased ability to degrade L-threonine, accumulating L-threonine in the culture liquor and recovering L-threonine therefrom.

摘要翻译： 本发明公开了用于生产L-苏氨酸的方法，该方法包括在培养基中培养能产生对赖福普胺，赖氨酸，甲硫氨酸，天冬氨酸和高丝氨酸中的至少一种具有抗性的L-苏氨酸的微生物，或 降低L-苏氨酸的降解能力，在培养液中积累L-苏氨酸并从其中回收L-苏氨酸。

公开(公告)号：US4729952A

公开(公告)日：1988-03-08

申请号：US582883

申请日：1984-02-23

申请人： Kiyoji Hattori ,  Yukinobu Kotani ,  Kuniki Kino

发明人： Kiyoji Hattori ,  Yukinobu Kotani ,  Kuniki Kino

IPC分类号： C12P13/14 ,  C12N1/20 ,  C12R1/13 ,  C12R1/15

CPC分类号： C12R1/14 ,  C12P13/14 ,  C12R1/15 ,  Y10S435/84 ,  Y10S435/843

摘要： A process is disclosed for producing L-glutamic acid, the process involves culturing a microorganism belonging to the genus Corynebacterium or Brevibacterium and having both an ability to produce L-glutamic acid and a resistance to .alpha.-naphthoquinoline, an antibiotic inhibiting energy metabolism or a precursor for ubiquinone biosynthesis in a nutrient medium until L-glutamic acid is accumulated in the resulting culture liquor, and recovering the L-glutamic acid therefrom.

公开(公告)号：US4725541A

公开(公告)日：1988-02-16

申请号：US583378

申请日：1984-02-24

申请人： Yukinobu Kotani ,  Kuniki Kino

发明人： Yukinobu Kotani ,  Kuniki Kino

IPC分类号： C12P13/24 ,  C12R1/15 ,  C12N1/20

CPC分类号： C12R1/15 ,  C12P13/24 ,  Y10S435/843

摘要： L-histidine is produced by culturing, in a nutrient medium, an L-histidine producing mutant microorganism belonging to the genus Corynebacterium. The mutant is resistant to a precursor for ubiquinone biosynthesis. L-histidine is accumulated in the culture liquor and is recovered therefrom.

摘要翻译： 通过在营养培养基中培养属于棒杆菌属的L-组氨酸产生突变体微生物来产生L-组氨酸。 突变体对泛醌生物合成的前体具有抗性。 L-组氨酸在培养液中积聚并从中回收。