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公开(公告)号：US20220291156A1
公开(公告)日：2022-09-15
申请号：US17664474
申请日：2022-05-23
发明人： Jeffrey Paulsen , Yi-Qiao Song
IPC分类号： G01N24/08 , G01R33/44 , G01R33/563 , G01V3/32
摘要： A method and system for determining a property of a substance using nuclear magnetic resonance (NMR) is described herein. The method includes applying a NMR pulse sequence to the substance. The NMR pulse sequence includes a first set of pulses and a second set of pulses. The first set of pulses and the second set of pulses encode for overlapping diffusion times. By overlapping diffusion times, the NMR pulse sequence can be used to measure a diffusion coefficient for a first diffusion time, a diffusion coefficient for a second diffusion time, and a correlation between the two overlapping diffusion times. This information, in turn, can be used to differentiate between intrinsic bulk diffusivity of the substance and the reduced diffusivity of the substance caused by restricted diffusion.
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公开(公告)号：US11340180B2
公开(公告)日：2022-05-24
申请号：US16298728
申请日：2019-03-11
发明人： Jeffrey Paulsen , Yi-Qiao Song
IPC分类号： G01V3/32 , G01N24/08 , G01R33/44 , G01R33/563
摘要： A method and system for determining a property of a substance using nuclear magnetic resonance (NMR) is described herein. The method includes applying a NMR pulse sequence to the substance. The NMR pulse sequence includes a first set of pulses and a second set of pulses. The first set of pulses and the second set of pulses encode for overlapping diffusion times. By overlapping diffusion times, the NMR pulse sequence can be used to measure a diffusion coefficient for a first diffusion time, a diffusion coefficient for a second diffusion time, and a correlation between the two overlapping diffusion times. This information, in turn, can be used to differentiate between intrinsic bulk diffusivity of the substance and the reduced diffusivity of the substance caused by restricted diffusion.
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公开(公告)号：US20150253454A1
公开(公告)日：2015-09-10
申请号：US14431843
申请日：2013-09-27
CPC分类号： G01V3/32 , E21B49/088 , G01N24/081 , G01N24/10 , G01R33/307 , G01R33/345 , G01R33/383 , G01R33/448 , G01R33/4608 , G01R33/4633
摘要： A coaxial nuclear magnetic resonance (NMR) probe and related methods are described herein. The coaxial NMR probe includes a housing with a fluid inlet, a fluid outlet, a longitudinal axis, and an interior volume. The housing contains a fluid sample that is analyzed by the probe. The coaxial NMR probe also includes an elongated conductor disposed along the longitudinal axis of the housing. The elongated conductor generates an oscillating electromagnetic field within the interior volume of the housing. The oscillating electromagnetic field produces a NMR signal within the fluid sample. The elongated conductor may also be used to receive this NMR signal. The NMR signal is then analyzed to determine information about the fluid sample. Various NMR pulse sequences for use with this coaxial probe and other coaxial probes are also described herein.
摘要翻译： 本文描述了同轴核磁共振（NMR）探针和相关方法。 同轴NMR探头包括具有流体入口，流体出口，纵向轴线和内部体积的壳体。 壳体包含被探针分析的流体样品。 同轴NMR探头还包括沿着壳体的纵向轴线设置的细长导体。 细长的导体在壳体的内部空间内产生振荡的电磁场。 振荡电磁场在流体样品内产生NMR信号。 细长导体也可用于接收该NMR信号。 然后分析NMR信号以确定关于流体样品的信息。 本文还描述了用于该同轴探针和其它同轴探针的各种NMR脉冲序列。
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公开(公告)号：US10228335B2
公开(公告)日：2019-03-12
申请号：US14586376
申请日：2014-12-30
发明人： Jeffrey Paulsen , Yi-Qiao Song
IPC分类号： G01N24/08 , G01R33/44 , G01R33/563 , G01V3/32
摘要： A method and system for determining a property of a substance using nuclear magnetic resonance (NMR) is described herein. The method includes applying a NMR pulse sequence to the substance. The NMR pulse sequence includes a first set of pulses and a second set of pulses. The first set of pulses and the second set of pulses encode for overlapping diffusion times. By overlapping diffusion times, the NMR pulse sequence can be used to measure a diffusion coefficient for a first diffusion time, a diffusion coefficient for a second diffusion time, and a correlation between the two overlapping diffusion times. This information, in turn, can be used to differentiate between intrinsic bulk diffusivity of the substance and the reduced diffusivity of the substance caused by restricted diffusion.
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公开(公告)号：US20160274204A1
公开(公告)日：2016-09-22
申请号：US15032241
申请日：2014-10-28
发明人： Yi-qiao Song , Jeffrey Paulsen , Donhee Ham , Dongwan Ha
CPC分类号： G01R33/543 , G01N24/081 , G01R33/3415 , G01R33/3607 , G01R33/3614 , G01R33/3621 , G01R33/3635 , G01V3/32
摘要： An integrated circuit is provided for use in conjunction with an external antenna. The integrated circuit includes a memory circuit, a pulse sequencer, an NMR transmitter circuit and an NMR receiver circuit. The memory circuit is configured to store user-defined parameter data pertaining to an excitation period and an acquisition period that are part of an NMR pulse sequence. The pulse sequencer and the NMR transmitter circuit are configured to cooperate to generate RF signals in accordance the user-defined parameter data stored in the memory circuit, wherein such RF signals are supplied to the external antenna for emitting excitation signals from the external antenna during the excitation period of the NMR pulse sequence. The NMR receiver circuit is configured to receive electrical signals generated by the external antenna during the acquisition period of the NMR pulse sequence.
摘要翻译： 提供与外部天线结合使用的集成电路。 集成电路包括存储器电路，脉冲序列发生器，NMR发射器电路和NMR接收器电路。 存储器电路被配置为存储关于作为NMR脉冲序列的一部分的激励周期和获取周期的用户定义的参数数据。 脉冲序列器和NMR发射器电路被配置为根据存储在存储器电路中的用户定义的参数数据进行协作以产生RF信号，其中这样的RF信号被提供给外部天线，用于在外部天线期间发射来自外部天线的激励信号 NMR脉冲序列的激发期。 NMR接收器电路被配置为在NMR脉冲序列的采集周期期间接收由外部天线产生的电信号。
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公开(公告)号：US10386530B2
公开(公告)日：2019-08-20
申请号：US14431843
申请日：2013-09-27
IPC分类号： G01R33/30 , G01V3/32 , E21B49/08 , G01N24/08 , G01R33/345 , G01R33/44 , G01R33/46 , G01N24/10 , G01R33/383
摘要： A coaxial nuclear magnetic resonance (NMR) probe and related methods are described herein. The coaxial NMR probe includes a housing with a fluid inlet, a fluid outlet, a longitudinal axis, and an interior volume. The housing contains a fluid sample that is analyzed by the probe. The coaxial NMR probe also includes an elongated conductor disposed along the longitudinal axis of the housing. The elongated conductor generates an oscillating electromagnetic field within the interior volume of the housing. The oscillating electromagnetic field produces a NMR signal within the fluid sample. The elongated conductor may also be used to receive this NMR signal. The NMR signal is then analyzed to determine information about the fluid sample. Various NMR pulse sequences for use with this coaxial probe and other coaxial probes are also described herein.
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公开(公告)号：US10295636B2
公开(公告)日：2019-05-21
申请号：US15032241
申请日：2014-10-28
发明人： Yi-qiao Song , Jeffrey Paulsen , Donhee Ham , Dongwan Ha
IPC分类号： G01R33/54 , G01N24/08 , G01R33/36 , G01V3/32 , G01R33/3415
摘要： An integrated circuit is provided for use in conjunction with an external antenna. The integrated circuit includes a memory circuit, a pulse sequencer, an NMR transmitter circuit and an NMR receiver circuit. The memory circuit is configured to store user-defined parameter data pertaining to an excitation period and an acquisition period that are part of an NMR pulse sequence. The pulse sequencer and the NMR transmitter circuit are configured to cooperate to generate RF signals in accordance the user-defined parameter data stored in the memory circuit, wherein such RF signals are supplied to the external antenna for emitting excitation signals from the external antenna during the excitation period of the NMR pulse sequence. The NMR receiver circuit is configured to receive electrical signals generated by the external antenna during the acquisition period of the NMR pulse sequence.
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公开(公告)号：US10132894B2
公开(公告)日：2018-11-20
申请号：US13736985
申请日：2013-01-09
发明人： Yi-Qiao Song , Fei Han , Jeffrey Paulsen
IPC分类号： G01R33/54 , G01N24/08 , G01R33/48 , G01R33/50 , G01R33/561
摘要： A method of investigating an object using nuclear magnetic resonance (NMR) equipment includes generating a one-dimensional projection of the object for each of a plurality of echoes utilizing echo train signal indications resulting from pulse sequences, and utilizing the plurality of one-dimensional projections, for each of the plurality of echoes, generating NMR image data for at least one location in the object. The NMR image data may be displayed. The displayed data may include a T2 decay curve, a T2 value display, a T2 distribution graph, or petrophysical data for at least one object location.
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9.发明授权公开(公告)号：US09823205B2
公开(公告)日：2017-11-21
申请号：US14543290
申请日：2014-11-17
发明人： Zhixiang Luo , Jeffrey Paulsen , Yi-Qiao Song
CPC分类号： G01N24/081 , G01R33/448 , G01V3/32
摘要： Methods and systems for determining surface relaxivity from nuclear magnetic resonance measurements relate to applying multiple nuclear magnetic resonance (NMR) diffusion editing Carr-Purcell-Meiboom-Gill (CPMG) pulse sequences to the porous medium, wherein the diffusion editing CPMG pulse sequences have a diffusion encoding time Δ; receiving NMR data generated by the pulse sequences; processing the received NMR data to obtain a distribution f(T2,D) for the diffusion encoding time Δ; repeating the applying, the receiving, and the processing at least one time for pulse sequences having different respective diffusion encoding times Δ to obtain respective distributions f(T2,D) corresponding respectively to the different diffusion encoding times Δ; and utilizing the respectively obtained distributions f(T2,D) to generate a surface relaxivity (ρ) determination.
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10.发明申请METHODS AND SYSTEMS FOR DETERMINING SURFACE RELAXIVITY OF A MEDIUM USING NUCLEAR MAGNETIC RESONANCE 有权用于确定使用核磁共振的介质的表面松弛度的方法和系统公开(公告)号：US20160139066A1
公开(公告)日：2016-05-19
申请号：US14543290
申请日：2014-11-17
发明人： Zhixiang Luo , Jeffrey Paulsen , Yi-Qiao Song
CPC分类号： G01N24/081 , G01R33/448 , G01V3/32
摘要： Methods and systems for determining surface relaxivity from nuclear magnetic resonance measurements relate to applying multiple nuclear magnetic resonance (NMR) diffusion editing Carr-Purcell-Meiboom-Gill (CPMG) pulse sequences to the porous medium, wherein the diffusion editing CPMG pulse sequences have a diffusion encoding time Δ; receiving NMR data generated by the pulse sequences; processing the received NMR data to obtain a distribution f(T2,D) for the diffusion encoding time Δ; repeating the applying, the receiving, and the processing at least one time for pulse sequences having different respective diffusion encoding times Δ to obtain respective distributions f(T2,D) corresponding respectively to the different diffusion encoding times Δ; and utilizing the respectively obtained distributions f(T2,D) to generate a surface relaxivity (ρ) determination.
摘要翻译： 用于从核磁共振测量确定表面弛豫度的方法和系统涉及将多核核磁共振（NMR）扩散编辑Carr-Purcell-Meiboom-Gill（CPMG）脉冲序列应用于多孔介质，其中扩散编辑CPMG脉冲序列具有 扩散编码时间 接收由脉冲序列产生的NMR数据; 处理接收到的NMR数据以获得扩散编码时间＆Dgr的分布f（T2，D）; 对具有不同的各自的扩散编码时间＆amp; Dgr的脉冲序列重复施加，接收和处理至少一次; 以获得分别对应于不同扩散编码时间和Dgr的各自的分布f（T2，D）; 并利用分别得到的分布f（T2，D）来产生表面弛豫（＆rgr;）确定。
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