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14 条记录 (耗时 0.043 秒)

    COMPOSITION, METHOD AND KIT FOR REDUCING BACKGROUND STAINING
    5.
    发明申请
    COMPOSITION, METHOD AND KIT FOR REDUCING BACKGROUND STAINING 审中-公开
    用于减少背景染色的组合物，方法和工具包

    公开(公告)号：US20080038773A1

    公开(公告)日：2008-02-14

    申请号：US11873281

    申请日：2007-10-16

    申请人： Brian Filanoski ,  I. Greenfield ,  James Hirsch

    发明人： Brian Filanoski ,  I. Greenfield ,  James Hirsch

    IPC分类号： G01N1/30 ,  C12Q1/00

    CPC分类号： G01N33/52 ,  G01N1/30

    摘要： Compositions, methods and kits are disclosed for improved staining of a cell or tissue with a dye-conjugate that binds specifically to a particular component of the cell or tissue. The compositions, methods and kits include a polymeric material that reduces non-specific binding of a dye-conjugate to components of the cell or tissue other than the particular component specifically bound by the dye-conjugate. In some embodiments, the polymeric material is a synthetic polymer or a naturally-occurring polymer that is substituted by multiple sulfate, sulfonate, phosphate and/or phosphonate groups.

    摘要翻译： 公开了组合物，方法和试剂盒，用于改善用特异性结合细胞或组织的特定组分的染料缀合物染色细胞或组织。 组合物，方法和试剂盒包括聚合物材料，其减少染料缀合物与除了由染料缀合物特异结合的特定组分以外的细胞或组织的组分的非特异性结合。 在一些实施方案中，聚合物材料是由多种硫酸盐，磺酸盐，磷酸盐和/或膦酸盐基团取代的合成聚合物或天然存在的聚合物。

    COMPOSITION, METHOD AND KIT FOR REDUCING BACKGROUND STAINING
    6.
    发明申请
    COMPOSITION, METHOD AND KIT FOR REDUCING BACKGROUND STAINING 审中-公开

    公开(公告)号：US20080038772A1

    公开(公告)日：2008-02-14

    申请号：US11873185

    申请日：2007-10-16

    申请人： Brian Filanoski ,  I. Greenfield ,  James Hirsch

    发明人： Brian Filanoski ,  I. Greenfield ,  James Hirsch

    IPC分类号： G01N1/30

    CPC分类号： G01N1/30 ,  C07D501/00 ,  G01N2001/302

    摘要： Compositions, methods and kits are disclosed for improved staining of a cell or tissue with a dye-conjugate that binds specifically to a particular component of the cell or tissue. The compositions, methods and kits include a polymeric material that reduces non-specific binding of a dye-conjugate to components of the cell or tissue other than the particular component specifically bound by the dye-conjugate. In some embodiments, the polymeric material is a synthetic polymer or a naturally-occurring polymer that is substituted by multiple sulfate, sulfonate, phosphate and/or phosphonate groups.

    Intraoral device
    7.
    发明申请
    Intraoral device 有权

    公开(公告)号：US20060084031A1

    公开(公告)日：2006-04-20

    申请号：US11295969

    申请日：2005-12-07

    申请人： James Hirsch ,  Thomas Hirsch

    发明人： James Hirsch ,  Thomas Hirsch

    IPC分类号： A61C17/06

    CPC分类号： A61C17/04 ,  A61C1/088 ,  A61C5/90 ,  A61C17/043

    摘要： An intraoral device includes a one-piece, flexible, injection molded body made of a single homogeneous material. The body includes upper front and rear flaps, and lower front and rear flaps. Upper edges of the front flaps and lower edges of the lower flaps are sealed by respective upper and lower parts of a patient's mouth to form upper and lower evacuation channels when the body is disposed within the patient's mouth. Evacuation holes in the flaps are in communication with the evacuation channels. A connection section is in communication with the evacuation channels and is configured to extend outside of the patient's mouth to connect with a vacuum source for evacuating fluid from the patient's mouth through the evacuation holes and the evacuation channels.

    Cooling device and method for intraoral device illumination source
    8.
    发明申请
    Cooling device and method for intraoral device illumination source 有权

    公开(公告)号：US20060063129A1

    公开(公告)日：2006-03-23

    申请号：US11223098

    申请日：2005-09-09

    申请人： James Hirsch

    发明人： James Hirsch

    IPC分类号： A61C17/06

    CPC分类号： A61C17/04 ,  A61C1/088 ,  A61C5/90 ,  A61C17/043

    摘要： A method of using a heat sink device with an intraoral illumination device includes inserting an intraoral illumination device at least partially in a patient's mouth, connecting a heat sink device to the intraoral illumination device, the heat sink device including an illumination device that emits light and heat when activated and a heat sink member thermally coupled to the illumination device; activating the illumination device so that light is transmitted to the intraoral illumination device and into the patient's mouth, aspirating fluid from the patient's mouth at negative pressure; and causing aspirated fluid to flow past the heat sink member at negative pressure so that heat is removed from the heat sink member, causing the illumination device to be cooled.

    DENTAL RETRACTOR
    9.
    发明公开
    DENTAL RETRACTOR 审中-公开

    公开(公告)号：US20230397803A1

    公开(公告)日：2023-12-14

    申请号：US17839414

    申请日：2022-06-13

    申请人： Brian Halleck ,  Michael Shinn ,  Jacob Swartz ,  James Hirsch ,  Amy Kerr ,  Shaun Valentine

    发明人： Brian Halleck ,  Michael Shinn ,  Jacob Swartz ,  James Hirsch ,  Amy Kerr ,  Shaun Valentine

    IPC分类号： A61B1/24 ,  A61C5/90

    CPC分类号： A61B1/24 ,  A61C5/90

    摘要： A dental retractor has molded flexural support members to provide upper lip, lower lip, and cheek retraction. The retraction provides unobstructed access and visibility for facial/labial areas of the mouth during dental procedures. The lips are prevented from touching gingival tissue and tooth structure. Lips and soft tissue are retracted and held safely away from dental tools. Labial retraction is provided by flexible members which, when positioned in the use position, provide elevation and retraction for the labial surfaces both maxillary and mandibular, the counteractive forces of the maxillary and mandibular support members keep the lips retracted and away from treatment areas. As the flexural support members are flexed for labial retraction, the medial portions of the support members bilaterally retract the cheeks due to the designed forces in the support members.

    HYPOCHLOROUS FOGGING OR MISTING APPARATUS AND METHODS
    10.
    发明申请
    HYPOCHLOROUS FOGGING OR MISTING APPARATUS AND METHODS 有权

    公开(公告)号：US20220202977A1

    公开(公告)日：2022-06-30

    申请号：US17393018

    申请日：2021-08-03

    申请人： James Hirsch ,  Shaun Valentine ,  Brian Halleck

    发明人： James Hirsch ,  Shaun Valentine ,  Brian Halleck

    IPC分类号： A61L2/22 ,  A61L2/26

    摘要： A disinfecting device is easy to use and can be easily mounted in a dental operatory or other similar environment. The device can include a removable solution chamber attached to a base unit. The solution chamber can be a refillable chamber or a disposable chamber. The base unit can receive pressurized air, typically from a standard connection present in the dental operatory, or a dental chair, or the like. The pressurized air can be used to deliver a mist or an electrostatic fog of the solution in the solution chamber out of a nozzle. A hose can connect the base unit with the nozzle. In use, the user can turn on the system and use an activation/deactivation mechanism to deliver the atomized mist or fog to all surfaces in the room.