中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

18 records (took 0.013 seconds)

    Methods of using IL-1 antagonists to treat autoinflammatory disease
    1.
    发明申请
    Methods of using IL-1 antagonists to treat autoinflammatory disease 有权
    使用IL-1拮抗剂治疗自身炎症性疾病的方法

    公开(公告)号：US20050272655A1

    公开(公告)日：2005-12-08

    申请号：US11144987

    申请日：2005-06-03

    Applicant: Scott Mellis ,  Margaret Karow ,  George Yancopoulos ,  Joanne Papadopoulos

    Inventor： Scott Mellis ,  Margaret Karow ,  George Yancopoulos ,  Joanne Papadopoulos

    IPC: A61K38/17 ,  C07K14/715

    CPC classification number: C07K14/7155 ,  A61K38/00 ,  A61K38/177 ,  A61K45/06 ,  A61K2300/00

    Abstract: Methods of treating, inhibiting, or ameliorating an autoinflammatory disorder, disease, or condition in a subject in need thereof, comprising administering to a subject in need a therapeutic amount of an interleukin 1 (IL-1) antagonist, wherein the autoinflammatory disorder, disease, or condition is treated, inhibited, or ameliorated. The IL-1 antagonist is a molecule capable of binding and inhibiting IL-1. The therapeutic methods are useful for treating a human adult or child suffering from Neonatal Onset Multisystem Inflammatory Disorder (NOMID/CINCA), Muckle-Wells Syndrome (MWS), Familial Cold Autoinflammatory Syndrome (FCAS), familial mediterranean fever (FMF), tumor necrosis factor receptor-associated periodic fever syndrome (TRAPS), or systemic onset juvenile idiopathic arthritis (Still's Disease).

    Abstract translation: 在有需要的受试者中治疗，抑制或改善自身炎性疾病，疾病或病症的方法，包括向需要治疗的受试者施用治疗量的白细胞介素1（IL-1）拮抗剂，其中所述自身炎性疾病，疾病 ，或条件得到治疗，抑制或改善。 IL-1拮抗剂是能够结合和抑制IL-1的分子。 治疗方法可用于治疗患有新生儿起始多系统炎症性疾病（NOMID / CINCA），Muckle-Wells综合征（MWS），家族性冷自身炎症综合征（FCAS），家族性地中海热（FMF），肿瘤坏死的成人或儿童 因子受体相关的周期性发热综合征（TRAPS）或全身性发作的幼年特发性关节炎（Still氏病）。

    METHODS OF USING IL-1 ANTAGONISTS TO TREAT AUTOINFLAMMATORY DISEASE
    3.
    发明申请
    METHODS OF USING IL-1 ANTAGONISTS TO TREAT AUTOINFLAMMATORY DISEASE 有权
    使用IL-1拮抗剂治疗自身免疫性疾病的方法

    公开(公告)号：US20110318342A1

    公开(公告)日：2011-12-29

    申请号：US13224372

    申请日：2011-09-02

    Applicant: Scott Mellis ,  Margaret Karow ,  George D. Yancopoulos ,  Joanne Papadopoulos

    Inventor： Scott Mellis ,  Margaret Karow ,  George D. Yancopoulos ,  Joanne Papadopoulos

    IPC: A61K39/395 ,  A61K38/48 ,  A61P37/06 ,  A61K38/16

    CPC classification number: C07K14/7155 ,  A61K38/00 ,  A61K38/177 ,  A61K45/06 ,  A61K2300/00

    Abstract: Methods of treating, inhibiting, or ameliorating an autoinflammatory disorder, disease, or condition in a subject in need thereof, comprising administering to a subject in need a therapeutic amount of an interleukin 1 (IL-1) antagonist, wherein the autoinflammatory disorder, disease, or condition is treated, inhibited, or ameliorated. The IL-1 antagonist is a molecule capable of binding and inhibiting IL-1. The therapeutic methods are useful for treating a human adult or child suffering from Neonatal Onset Multisystem Inflammatory Disorder (NOMID/CINCA), Muckle-Wells Syndrome (MWS), Familial Cold Autoinflammatory Syndrome (FCAS), familial mediterranean fever (FMF), tumor necrosis factor receptor-associated periodic fever syndrome (TRAPS), or systemic onset juvenile idiopathic arthritis (Still's Disease).

    Abstract translation: 在有需要的受试者中治疗，抑制或改善自身炎性疾病，疾病或病症的方法，包括向需要治疗的受试者施用治疗量的白细胞介素1（IL-1）拮抗剂，其中所述自身炎性疾病，疾病 ，或条件得到治疗，抑制或改善。 IL-1拮抗剂是能够结合和抑制IL-1的分子。 治疗方法可用于治疗患有新生儿起始多系统炎症性疾病（NOMID / CINCA），Muckle-Wells综合征（MWS），家族性冷自身炎症综合征（FCAS），家族性地中海热（FMF），肿瘤坏死的成人或儿童 因子受体相关的周期性发热综合征（TRAPS）或全身性发作的幼年特发性关节炎（Still氏病）。

    Methods for identifying a candidate for treatment of obesity
    6.
    发明申请
    Methods for identifying a candidate for treatment of obesity 有权
    识别肥胖症治疗候选人的方法

    公开(公告)号：US20060008832A1

    公开(公告)日：2006-01-12

    申请号：US11177860

    申请日：2005-07-08

    Applicant: Scott Mellis

    Inventor： Scott Mellis

    IPC: C12Q1/68

    CPC classification number: C12Q1/6883 ,  C12Q1/6881 ,  C12Q2600/106 ,  C12Q2600/156

    Abstract: Methods of identifying human subjects for treatment of obesity or an obesity-related condition with ciliary neurotrophic factor (CNTF) or a CNTF-related molecule, such as Axokine®, based on the presence of human leukocyte antigen (HLA) DRβ1 allele 1501 or the absence of HLA DRβ1 allele 0701.

    Abstract translation: 基于人白细胞抗原（HLA）DRbeta1等位基因1501的存在，鉴定用于治疗肥胖或与睫状神经营养因子（CNTF）或CNTF相关分子（例如Axokine）的肥胖相关状况的人类受试者的方法 或不存在HLA DRbeta1等位基因0701。

    Methods of using IL-1 antagonists to treat autoinflammatory disease
    7.
    发明授权
    Methods of using IL-1 antagonists to treat autoinflammatory disease 有权
    使用IL-1拮抗剂治疗自身炎症性疾病的方法

    公开(公告)号：US08414876B2

    公开(公告)日：2013-04-09

    申请号：US13224372

    申请日：2011-09-02

    Applicant: Scott Mellis ,  Margaret Karow ,  George D. Yancopoulos ,  Joanne Papadopoulos

    Inventor： Scott Mellis ,  Margaret Karow ,  George D. Yancopoulos ,  Joanne Papadopoulos

    IPC: A61K38/16 ,  A61K38/19 ,  A61K45/00 ,  C12P21/00

    CPC classification number: C07K14/7155 ,  A61K38/00 ,  A61K38/177 ,  A61K45/06 ,  A61K2300/00

    Abstract: Methods of treating, inhibiting, or ameliorating an autoinflammatory disorder, disease, or condition in a subject in need thereof, comprising administering to a subject in need a therapeutic amount of an interleukin 1 (IL-1) antagonist, wherein the autoinflammatory disorder, disease, or condition is treated, inhibited, or ameliorated. The IL-1 antagonist is a molecule capable of binding and inhibiting IL-1. The therapeutic methods are useful for treating a human adult or child suffering from Neonatal Onset Multisystem Inflammatory Disorder (NOMID/CINCA), Muckle-Wells Syndrome (MWS), Familial Cold Autoinflammatory Syndrome (FCAS), familial mediterranean fever (FMF), tumor necrosis factor receptor-associated periodic fever syndrome (TRAPS), or systemic onset juvenile idiopathic arthritis (Still's Disease).

    Abstract translation: 在有需要的受试者中治疗，抑制或改善自身炎性疾病，疾病或病症的方法，包括向需要治疗的受试者施用治疗量的白细胞介素1（IL-1）拮抗剂，其中所述自身炎性疾病，疾病 ，或条件得到治疗，抑制或改善。 IL-1拮抗剂是能够结合和抑制IL-1的分子。 治疗方法可用于治疗患有新生儿起始多系统炎症性疾病（NOMID / CINCA），Muckle-Wells综合征（MWS），家族性冷自身炎症综合征（FCAS），家族性地中海热（FMF），肿瘤坏死的成人或儿童 因子受体相关的周期性发热综合征（TRAPS）或全身性发作的幼年特发性关节炎（Still氏病）。

    Methods of using IL-1 antagonists to treat autoinflammatory disease
    9.
    发明授权
    Methods of using IL-1 antagonists to treat autoinflammatory disease 有权
    使用IL-1拮抗剂治疗自身炎症性疾病的方法

    公开(公告)号：US07459426B2

    公开(公告)日：2008-12-02

    申请号：US11144987

    申请日：2005-06-03

    Applicant: Scott Mellis ,  Margaret Karow ,  George D. Yancopoulos ,  Joanne Papadopoulos

    Inventor： Scott Mellis ,  Margaret Karow ,  George D. Yancopoulos ,  Joanne Papadopoulos

    IPC: A61K38/00 ,  A61K38/19 ,  C12N15/00

    CPC classification number: C07K14/7155 ,  A61K38/00 ,  A61K38/177 ,  A61K45/06 ,  A61K2300/00

    Abstract: Methods of treating, inhibiting, or ameliorating an autoinflammatory disorder, disease, or condition in a subject in need thereof, comprising administering to a subject in need a therapeutic amount of an interleukin 1 (IL-1) antagonist, wherein the autoinflammatory disorder, disease, or condition is treated, inhibited, or ameliorated. The IL-1 antagonist is a molecule capable of binding and inhibiting IL-1. The therapeutic methods are useful for treating a human adult or child suffering from Neonatal Onset Multisystem Inflammatory Disorder (NOMID/CINCA), Muckle-Wells Syndrome (MWS), Familial Cold Autoinflammatory Syndrome (FCAS), familial mediterranean fever (FMF), tumor necrosis factor receptor-associated periodic fever syndrome (TRAPS), or systemic onset juvenile idiopathic arthritis (Still's Disease).

    Abstract translation: 在有需要的受试者中治疗，抑制或改善自身炎性疾病，疾病或病症的方法，包括向需要治疗的受试者施用治疗量的白细胞介素1（IL-1）拮抗剂，其中所述自身炎性疾病，疾病 ，或条件得到治疗，抑制或改善。 IL-1拮抗剂是能够结合和抑制IL-1的分子。 治疗方法可用于治疗患有新生儿起始多系统炎症性疾病（NOMID / CINCA），Muckle-Wells综合征（MWS），家族性冷自身炎症综合征（FCAS），家族性地中海热（FMF），肿瘤坏死的成人或儿童 因子受体相关的周期性发热综合征（TRAPS）或全身性发作的幼年特发性关节炎（Still氏病）。

Patent Agency Ranking