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1.Inhibition Of Raf Kinase Using Symmetrical And Unsymmetrical Substituted Diphenyl Ureas 审中-公开
标题翻译: 使用对称和非对称取代的二苯基脲对Raf激酶的抑制公开(公告)号:US20080269265A1
公开(公告)日:2008-10-30
申请号:US12145679
申请日:2008-06-25
申请人: Scott Miller , Martin Osterhout , Jacques Dumas , Uday Khire , Timothy B. Lowinger , Bernd Riedl , William J. Scott , Roger A. Smith , Jill E. Wood , David Gunn , Martha Rodriguez , Ming Wang , Tiffany Turner , Catherine Brennan
发明人: Scott Miller , Martin Osterhout , Jacques Dumas , Uday Khire , Timothy B. Lowinger , Bernd Riedl , William J. Scott , Roger A. Smith , Jill E. Wood , David Gunn , Martha Rodriguez , Ming Wang , Tiffany Turner , Catherine Brennan
IPC分类号: A61K31/17 , C07D213/70 , C07D213/63 , C07D409/12 , C07D401/12 , C07D277/68 , C07D215/20 , C07D239/38 , A61P35/00 , A61K31/505 , A61K31/47 , A61K31/444 , A61K31/4439 , A61K31/4436 , A61K31/428
CPC分类号: C07D409/12 , C07C275/30 , C07C275/34 , C07C275/36 , C07C275/38 , C07C275/40 , C07D213/40 , C07D213/50 , C07D213/68 , C07D213/69 , C07D213/70 , C07D213/81 , C07D213/89 , C07D215/20 , C07D239/38 , C07D277/68 , C07D317/64 , C07D401/04 , C07D401/12
摘要: This invention relates to the use of a group of aryl ureas in treating raf mediated diseases, and pharmaceutical compositions for use in such therapy.
摘要翻译: 本发明涉及一组芳基脲在治疗raf介导的疾病中的用途,以及用于此类治疗的药物组合物。
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2.INHIBITION OF P38 KINASE USING SYMMETRICAL AND UNSYMMETRICAL DIPHENYL UREAS 审中-公开
标题翻译: 使用对称和非对称二苯醚类尿素抑制P38激酶公开(公告)号:US20090093526A1
公开(公告)日:2009-04-09
申请号:US11932397
申请日:2007-10-31
申请人: Scott Miller , Martin Osterhout , Jacques Dumas , Uday Khire , Timothy B. Lowinger , William J. Scott , Roger A. Smith , Jill E. Wood , David E. Gunn , Holia Hatoum-Mokdad , Marell Rodriguez , Robert Sibley , Ming Wang , Tiffany Turner , Catherine Brennan
发明人: Scott Miller , Martin Osterhout , Jacques Dumas , Uday Khire , Timothy B. Lowinger , William J. Scott , Roger A. Smith , Jill E. Wood , David E. Gunn , Holia Hatoum-Mokdad , Marell Rodriguez , Robert Sibley , Ming Wang , Tiffany Turner , Catherine Brennan
IPC分类号: A61K31/40 , A61K31/44 , C07D207/36 , C07D213/04 , A61P19/02
CPC分类号: A61K31/17 , A61K31/341 , A61K31/381 , A61K31/4035 , A61K31/44 , A61K31/5375 , Y02A50/411
摘要: This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases and proteolytic enzyme mediated diseases, and pharmaceutical compositions for use in such therapy.
摘要翻译: 本发明涉及一组芳基脲在治疗细胞因子介导的疾病和蛋白水解酶介导的疾病中的用途,以及用于这种治疗的药物组合物。
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3.Inhibition of p38 kinase using symmetrical and unsymmetrical diphenyl ureas 失效
标题翻译: 使用对称和不对称二苯脲抑制p38激酶公开(公告)号:US07517880B2
公开(公告)日:2009-04-14
申请号:US10060396
申请日:2002-02-01
申请人: Scott Miller , Martin Osterhout , Jacques Dumas , Uday Khire , Timothy B. Lowinger , William J. Scott , Roger A. Smith , Jill E. Wood , David E. Gunn , Holia Hatoum-Mokdad , Marell Rodriguez , Robert Sibley , Ming Wang , Tiffany Turner , Catherine Brennan
发明人: Scott Miller , Martin Osterhout , Jacques Dumas , Uday Khire , Timothy B. Lowinger , William J. Scott , Roger A. Smith , Jill E. Wood , David E. Gunn , Holia Hatoum-Mokdad , Marell Rodriguez , Robert Sibley , Ming Wang , Tiffany Turner , Catherine Brennan
IPC分类号: A61K31/40 , A61K31/44 , A61K31/535 , C07D333/22 , C07D233/61
CPC分类号: A61K31/17 , A61K31/341 , A61K31/381 , A61K31/4035 , A61K31/44 , A61K31/5375 , Y02A50/411
摘要: This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases and proteolytic enzyme mediated diseases, and pharmaceutical compositions for use in such therapy.
摘要翻译: 本发明涉及一组芳基脲在治疗细胞因子介导的疾病和蛋白水解酶介导的疾病中的用途,以及用于这种治疗的药物组合物。
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公开(公告)号:US20080058519A1
公开(公告)日:2008-03-06
申请号:US11558616
申请日:2006-11-10
申请人: Martin Osterhout , Frank Roschangar
发明人: Martin Osterhout , Frank Roschangar
IPC分类号: C07D407/02 , C07D417/14
CPC分类号: C07D405/04 , A61K31/517 , A61K31/519 , C07D417/04 , C07D471/04
摘要: Ditosylate salts of 4-quinazolineamines are described as well as methods of using the same in the treatment of disorders characterized by aberrant erbB family PTK activity.
摘要翻译: 描述4-喹唑啉胺的二甲苯磺酸盐以及用于治疗以异常erbB家族PTK活性为特征的疾病的方法。
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