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    System and method of a gaming machine with special bonus attraction
    1.
    发明申请
    System and method of a gaming machine with special bonus attraction 审中-公开
    具有特殊奖励吸引力的游戏机的系统和方法

    公开(公告)号：US20060160624A1

    公开(公告)日：2006-07-20

    申请号：US11333831

    申请日：2006-01-17

    申请人： Scott Slomiany ,  Duncan Brown ,  Lawrence DeMar

    发明人： Scott Slomiany ,  Duncan Brown ,  Lawrence DeMar

    IPC分类号： A63F9/24

    CPC分类号： G07F17/3281 ,  G07F17/32 ,  G07F17/3267

    摘要： The present invention includes a first game of chance, or base (primary) game, with a particular result or outcome that provides the player with the opportunity to play a second game, or bonus game. The bonus game is not played on the same gaming machine as the base game, but played on a bonus game attraction device. The player must physically leave the gaming machine of the first game to play the bonus game on the attraction device. The bonus game is distinct from the first game in that it is an entirely different game, with a different object and outcome, than the first game. The addition of a large bonus attraction device is a great enhancement to playing a wagering game in a casino environment.

    摘要翻译： 本发明包括机会或基础（主要）游戏的第一游戏，具有为玩家提供播放第二游戏或奖励游戏的机会的特定结果或结果。 奖金游戏不是在与基本游戏相同的游戏机上玩，而是在一个奖金游戏吸引装置上玩。 玩家必须在第一场比赛中离开游戏机才能在吸引装置上玩游戏。 奖金游戏与第一场比赛不同，因为它与第一场比赛是完全不同的游戏，具有不同的对象和结果。 增加一个大的奖励吸引装置是在赌场环境中玩一个投注游戏的一个很大的提高。

    Computerized game with cascading strategy and full information
    2.
    发明申请
    Computerized game with cascading strategy and full information 有权
    具有级联策略和完整信息的电脑游戏

    公开(公告)号：US20080039171A1

    公开(公告)日：2008-02-14

    申请号：US11973098

    申请日：2007-10-05

    申请人： Scott Slomiany ,  Lawrence DeMar ,  Duncan Brown

    发明人： Scott Slomiany ,  Lawrence DeMar ,  Duncan Brown

    IPC分类号： A63F9/24

    CPC分类号： G07F17/32 ,  G07F17/3293 ,  G07F17/3295

    摘要： A gaming machine and method for operating the same has gameplay elements provided in a manner that can be visualized, with the gameplay elements having a specific nature which is revealed to the player at a beginning to the game. That is, the player knows the value, or ranking, or position, etc., of the gameplay elements upon inception of the game. In a base level for the game of the gaming machine, no unknown gameplay element or random event is injected into the gameplay elements. This is a full information format for the gaming machine and method, and success is measured by the player's ability to manipulate the gameplay elements presented. A gaming machine and a method for operating the same is also provided with the gameplay elements once again having a specific nature which is known to the player at a start to game play, and in a preferred embodiment not subject thereafter to a random or unknown event, with the gameplay elements being arranged in one of a variety of different arrangements presenting a plurality of choices to a player for subsequent play of the elements. Outcome of the game is dependent upon the choices made by the player, with a given choice potentially influencing the next choice that may be available. Embodiments of the invention in the form of a checkers game and in the form of a poker-type game are disclosed, among others.

    摘要翻译： 用于操作该游戏机的游戏机和方法具有以可视化的方式提供的游戏元素，游戏元素具有特定的性质，游戏开始时向玩家显露。 也就是说，玩家知道游戏开始时游戏元素的价值，排名或位置等。 在游戏机游戏的基础水平中，没有未知的游戏元素或随机事件被注入游戏元素中。 这是游戏机和方法的完整信息格式，成功通过玩家操纵游戏元素的能力来衡量。 游戏机和操作该游戏机的方法还具有游戏元素，其再次具有游戏开始时游戏玩家已知的特定性质，并且在优选实施例中不受随机或未知事件影响 游戏元素以各种不同的布置方式布置成向播放器呈现多个选择以便随后播放元素。 游戏的结果取决于玩家的选择，给定的选择潜在地影响可能可用的下一个选择。 本发明的实施例以跳棋游戏的形式并以扑克式游戏的形式进行了公开。

    System and method of an interactive multiple participant game
    3.
    发明申请
    System and method of an interactive multiple participant game 审中-公开
    交互式多参与游戏的系统和方法

    公开(公告)号：US20060121971A1

    公开(公告)日：2006-06-08

    申请号：US11296840

    申请日：2005-12-06

    申请人： Scott Slomiany ,  Lawrence DeMar ,  Duncan Brown ,  Steven Katz

    发明人： Scott Slomiany ,  Lawrence DeMar ,  Duncan Brown ,  Steven Katz

    IPC分类号： A63F9/24

    CPC分类号： G07F17/3276 ,  G07F17/32 ,  G07F17/3288 ,  G07F17/3293 ,  G07F17/3295 ,  G07F17/34

    摘要： A plurality of linked gaming machines are disclosed that enhance the community participation and enjoyment of a game on multiple gaming machines. Players participate in an interactive game, either simultaneously, alternatively or in a systematic sequence, as a group or community. The participating players compete in the game such that the actions and results of each player affect the other players in the community. The interactive game combines skill and luck to improve play of the game. The interactive game could be a bonus game which players need to qualify in order to participate. If a player does not qualify, a wager can be placed to participate in the game. Players with different wagers can participate in the same game and players can wager on the outcomes of other players.

    摘要翻译： 公开了多个连接的游戏机，其增强了在多个游戏机上的游戏的社区参与和享受。 作为一个团体或社区，玩家可以同时或以系统的顺序参与互动游戏。 参赛者参加比赛，每个选手的动作和结果都会影响社区其他玩家。 互动游戏结合了技能和运气来改善游戏的玩法。 互动游戏可能是玩家需要参加资格的奖金游戏。 如果玩家不符合资格，可以投注一下参与比赛。 不同赌注的玩家可以参加同一场比赛，玩家可以对其他玩家的成果投下赌注。

    Chain reaction game
    4.
    发明申请
    Chain reaction game 有权

    公开(公告)号：US20060205473A1

    公开(公告)日：2006-09-14

    申请号：US11412527

    申请日：2006-04-27

    申请人： Benjamin Gomez ,  Duncan Brown ,  Scott Slomiany ,  Lawrence DeMar

    发明人： Benjamin Gomez ,  Duncan Brown ,  Scott Slomiany ,  Lawrence DeMar

    IPC分类号： A63F9/24

    CPC分类号： G07F17/32

    摘要： A game, gaming machine apparatus and game method wherein game elements are assigned to a matrix of game element locations. Play is initiated by evaluating the game elements for predetermined transformative conditions, such as a match of game elements. If a transformative condition is found, the game element(s) are transformed with at least one being removed from the matrix. The remaining game elements are moved, if permitted, according to a movement methodology. The steps of evaluating, transforming, removing, and moving the remaining game elements are repeated so long as a transformation is subsequently available for continued gameplay.

    Multi-stage multi-bet game, gaming device and method
    5.
    发明申请
    Multi-stage multi-bet game, gaming device and method 有权
    多级多投注游戏，游戏设备和方法

    公开(公告)号：US20050250578A1

    公开(公告)日：2005-11-10

    申请号：US11182407

    申请日：2005-07-15

    申请人： Scott Slomiany ,  Lawrence DeMar ,  Duncan Brown

    发明人： Scott Slomiany ,  Lawrence DeMar ,  Duncan Brown

    IPC分类号： A63F13/00 ,  G07F17/32

    CPC分类号： G07F17/3244 ,  G07F17/3262 ,  G07F17/3267 ,  G07F17/3293

    摘要： A game is comprised of a plurality of stages. Each operation of the game begins with the operation of a first stage. Depending on the outcome of the first stage the game may be over, or there may be an operation of a second stage. Depending on the outcome of the second stage, the game may be over or there may be an operation of another stage. This sequence continues until the game ends or until the final (nth) stage has been operated, at which time the game ends. Wagers are made on successive stages of the multi-stage game. Each stage of the game may typically have its own paytable or payout scheme, and its own expected return. A bet made on a stage of the game which is not played is lost in the preferred form of the invention. One embodiment is a three stage, multi-line, multi-coin video slot machine. The same game format (slots) with the same paytable is operated on three stages, with increasing payout multipliers at each stage providing an increasing amount to win at the higher stages. The “spin” at each stage is independent of the previous stages. The second embodiment is a multi-stage Five-Card Stud poker game. Each stage is again independent of the previous stage. A variation of this game is also shown which uses the same paytable on each stage, but combined with a mechanism to increase the “hit” rate. A third embodiment is a Draw poker game that combines the concepts of the Stud poker embodiment with the decisions and optimal play analysis that are integral to Draw poker. The fourth embodiment is a dice game which has been adapted to provide a high dependency between the first stage and the next stages.

    摘要翻译： 游戏由多个阶段构成。 游戏的每个操作开始于第一阶段的操作。 根据第一阶段的结果，游戏可能已经结束，或者可能存在第二阶段的操作。 根据第二阶段的结果，游戏可能已经结束，或者可能存在另一个阶段的操作。 该序列一直持续到游戏结束或直到最后（n th ）阶段被操作，此时游戏结束。 赌注是在多阶段游戏的连续阶段进行的。 游戏的每个阶段通常可以有自己的付款方式或支付方案，以及自己的预期回报。 在本发明的优选形式中，在游戏舞台上进行的未被玩过的赌注丢失。 一个实施例是三阶段多线多币投影视频老虎机。 相同的游戏格式（槽位）具有相同的付款方式，分三个阶段进行，每个阶段的支付乘数越多，越高越好。 每个阶段的“旋转”与以前的阶段无关。 第二个实施例是一个多阶段五卡牌扑克游戏。 每个阶段再次独立于前一阶段。 还显示了这种游戏的变体，其在每个阶段使用相同的支付方式，但结合增加“命中率”的机制。 第三个实施例是绘制扑克游戏，其结合了扑克扑克实施例的概念与决定和最佳游戏分析，它们是Draw扑克组成部分。 第四实施例是一种骰子游戏，其适于在第一阶段和下一阶段之间提供高依赖性。

    RNA INTERFERENCE MEDIATED INHIBITION OF ISOCITRATE DEHYDROGENASE (IDH1) GENE EXPRESSION
    6.
    发明申请
    RNA INTERFERENCE MEDIATED INHIBITION OF ISOCITRATE DEHYDROGENASE (IDH1) GENE EXPRESSION 有权
    RNA干扰介导的异烟肼脱氢酶（IDH1）基因表达的抑制

    公开(公告)号：US20140094503A1

    公开(公告)日：2014-04-03

    申请号：US14123822

    申请日：2012-06-01

    申请人： Yong Ma ,  Duncan Brown ,  Steven Bartz

    发明人： Yong Ma ,  Duncan Brown ,  Steven Bartz

    IPC分类号： C12N15/113

    CPC分类号： C12N15/1137 ,  C07H21/02 ,  C12N2310/14 ,  C12N2310/315 ,  C12N2310/317 ,  C12N2310/321 ,  C12N2310/332 ,  C12N2310/3521 ,  C12N2310/3533 ,  C12Y101/01042 ,  C12N2310/322

    摘要： The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of IDH1 and mutant IDH1 gene expression and/or activity, and/or modulate an IDH1 or mutant IDH1 gene expression pathway. Specifically, the invention relates to double-stranded nucleic acid molecules, including small nucleic acid molecules such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules, that are capable of mediating or that mediate RNA interference (RNAi) against IDH1 or mutant IDH1 gene expression.

    摘要翻译： 本发明涉及用于研究，诊断和治疗响应于IDH1和突变体IDH1基因表达和/或活性的调节和/或调节IDH1或突变体的性状，疾病和病症的化合物，组合物和方法 IDH1基因表达途径。 具体地说，本发明涉及双链核酸分子，包括小核酸分子，如短干扰核酸（siNA），短干扰RNA（siRNA），双链RNA（dsRNA），微RNA（miRNA） 和短发夹RNA（shRNA）分子，其能够介导或介导针对IDH1或突变体IDH1基因表达的RNA干扰（RNAi）。