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公开(公告)号：US20070212702A1
公开(公告)日：2007-09-13
申请号：US11519397
申请日：2006-09-12
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Xiao-Wei Sun , Sven Perner , Lee Charles , Mark Rubin
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Xiao-Wei Sun , Sven Perner , Lee Charles , Mark Rubin
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
摘要翻译： 描述了前列腺癌中雄激素调节基因和ETS家族成员基因的复发基因融合。 还提供了在前列腺癌诊断，研究和治疗中具有效用的组合物和方法。
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公开(公告)号：US20110034677A1
公开(公告)日：2011-02-10
申请号：US12650164
申请日：2009-12-30
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
摘要翻译： 描述了前列腺癌中雄激素调节基因和ETS家族成员基因的复发基因融合。 还提供了在前列腺癌诊断，研究和治疗中具有效用的组合物和方法。
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公开(公告)号：US20130040858A1
公开(公告)日：2013-02-14
申请号：US13483157
申请日：2012-05-30
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
摘要翻译： 描述了前列腺癌中雄激素调节基因和ETS家族成员基因的复发基因融合。 还提供了在前列腺癌诊断，研究和治疗中具有效用的组合物和方法。
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公开(公告)号：US08580509B2
公开(公告)日：2013-11-12
申请号：US13483176
申请日：2012-05-30
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
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公开(公告)号：US09284609B2
公开(公告)日：2016-03-15
申请号：US13483157
申请日：2012-05-30
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
IPC分类号： C12P19/34 , C07H21/04 , C12Q1/68 , C12N15/113 , G01N33/574
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
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公开(公告)号：US08211645B2
公开(公告)日：2012-07-03
申请号：US12650164
申请日：2009-12-30
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
摘要翻译： 描述了前列腺癌中雄激素调节基因和ETS家族成员基因的复发基因融合。 还提供了在前列腺癌诊断，研究和治疗中具有效用的组合物和方法。
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公开(公告)号：US08969527B2
公开(公告)日：2015-03-03
申请号：US13483142
申请日：2012-05-30
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
IPC分类号： C07K16/00 , C12Q1/68 , C12N15/113 , G01N33/574
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
摘要翻译： 描述了前列腺癌中雄激素调节基因和ETS家族成员基因的复发基因融合。 还提供了在前列腺癌诊断，研究和治疗中具有效用的组合物和方法。
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公开(公告)号：US20120296070A1
公开(公告)日：2012-11-22
申请号：US13483142
申请日：2012-05-30
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
IPC分类号： C07K16/18
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
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公开(公告)号：US20120295809A1
公开(公告)日：2012-11-22
申请号：US13483176
申请日：2012-05-30
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
摘要翻译： 描述了前列腺癌中雄激素调节基因和ETS家族成员基因的复发基因融合。 还提供了在前列腺癌诊断，研究和治疗中具有效用的组合物和方法。
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公开(公告)号：US07718369B2
公开(公告)日：2010-05-18
申请号：US11519397
申请日：2006-09-12
申请人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
发明人： Scott Tomlins , Daniel Rhodes , Arul Chinnaiyan , Rohit Mehra , Mark A. Rubin , Xiao-Wei Sun , Sven Perner , Charles Lee , Francesca Demichelis
CPC分类号： C12Q1/6886 , A01K67/0275 , A01K2217/072 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , C07K14/82 , C07K2319/00 , C12N9/6424 , C12N9/6445 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , G01N33/57434 , Y10S435/81
摘要： Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.
摘要翻译： 描述了前列腺癌中雄激素调节基因和ETS家族成员基因的复发基因融合。 还提供了在前列腺癌诊断，研究和治疗中具有效用的组合物和方法。
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