公开(公告)号：US11591644B2

公开(公告)日：2023-02-28

申请号：US16480521

申请日：2018-01-25

申请人： Sense Biodetection Limited

发明人： Henry John Lamble ,  David Lloyd ,  Christopher Egan

IPC分类号： C12Q1/6844 ,  C12Q1/682

摘要： The present invention relates to methods for the detection of nucleic acids of defined sequence and kits for use in said methods. The methods employ nicking agent(s), polymerase and oligonucleotide probes to produce probe fragments in the presence of a target nucleic acid.

公开(公告)号：US20200002756A1

公开(公告)日：2020-01-02

申请号：US16480521

申请日：2018-01-25

申请人： Sense Biodetection Limited

发明人： Henry John Lamble ,  David Lloyd ,  Christopher Egan

IPC分类号： C12Q1/6844 ,  C12Q1/682

摘要： The present invention relates to methods for the detection of nucleic acids of defined sequence and kits for use in said methods. The methods employ nicking agent(s), polymerase and oligonucleotide probes to produce probe fragments in the presence of a target nucleic acid.

公开(公告)号：US20180216157A1

公开(公告)日：2018-08-02

申请号：US15747130

申请日：2016-07-22

申请人： Sense Biodetection Limited

发明人： Henry John Lamble ,  Christopher Egan ,  David Lloyd ,  Eryk Dunski

IPC分类号： C12Q1/682

CPC分类号： C12Q1/682 ,  Y02A50/52 ,  Y02A50/58 ,  C12Q2521/307 ,  C12Q2537/149 ,  C12Q2521/301 ,  C12Q2537/155

摘要： The present invention relates to methods for the detection of nucleic acids of defined sequence, and compositions and kits for use in said methods. The methods employ nicking agent(s) and a sequential series of oligonucleotide probes to produce probe fragments in the presence of a target nucleic acid.