公开(公告)号：US20110318398A1

公开(公告)日：2011-12-29

申请号：US13114933

申请日：2011-05-24

申请人： Seong Kweon Lee ,  Jueun Song ,  Young Dae Park ,  Sung-Hee Cho

发明人： Seong Kweon Lee ,  Jueun Song ,  Young Dae Park ,  Sung-Hee Cho

IPC分类号： A61K8/11 ,  A61Q19/00 ,  A61Q19/02 ,  A61K8/97

CPC分类号： A61K8/97 ,  A61K2800/522 ,  A61K2800/85 ,  A61Q19/00 ,  A61Q19/02

摘要： The present invention relates to a cosmetic composition comprising a composite prepared by molecularly encapsulating a fermented sumac (Rhus javanica L.) extract with a cyclodextrin derivative as an active ingredient. More particularly, the present invention relates to a skin-whitening or antioxidant composition comprising a composite prepared by molecularly encapsulating a fermented sumac (Rhus javanica L.) extract with hydroxypropyl-β-cyclodextrin as an active ingredient. The composition of the present invention exhibits better skin-whitening and antioxidant effect than the existing cosmetic composition comprising 4-n-butylresorcinol, while having better stability. Further, since it is originated from natural materials with much less skin irritation, it can be effectively used to prepare functional skin-whitening and antioxidant cosmetic products.

摘要翻译： 本发明涉及一种化妆品组合物，其包含通过以环糊精衍生物作为活性成分分解封装发酵的漆树（罗汉尼卡）提取物而制备的复合物。 更具体地说，本发明涉及一种皮肤增白剂或抗氧化剂组合物，其包含通过以羟丙基-β-环糊精作为活性成分将发酵的漆树胶（Rhus javanica L.）提取物分子包封制备的复合物。 与现有的包含4-正丁基间苯二酚的化妆品组合物相比，本发明的组合物具有更好的皮肤美白和抗氧化作用，同时具有更好的稳定性。 此外，由于其起源于具有少许皮肤刺激性的天然材料，因此可有效地用于制备功能性美白和抗氧化的化妆品。

公开(公告)号：US20110318397A1

公开(公告)日：2011-12-29

申请号：US13114904

申请日：2011-05-24

申请人： Seong Kweon Lee ,  Jueun Song ,  Young Dae Park ,  Sung-Hee Cho

发明人： Seong Kweon Lee ,  Jueun Song ,  Young Dae Park ,  Sung-Hee Cho

IPC分类号： A61K8/63 ,  C07J17/00 ,  A61Q19/00 ,  C12P33/20

CPC分类号： A61K8/63 ,  A61K8/97 ,  A61K8/99 ,  A61Q19/08 ,  C07J9/00 ,  C07J17/005

摘要： The present invention relates to a method for preparing high-purity ginsenoside Rd using Lactobacillus casei, more particularly to a method for preparing high-purity ginsenoside Rd using Lactobacillus casei and an anti-wrinkle cosmetic composition comprising the high-purity ginsenoside Rd as an active ingredient. Since the method of the present invention is simple and can economically prepare high-purity ginsenoside Rd extract, it may make the best use of anti-wrinkle effect of the ginsenoside Rd. In addition, the present invention can increase stability and decrease skin irritation by preparing water-soluble molecular capsule of high-purity ginsenoside Rd, thereby having advantage of increasing applicability ginsenoside Rd radically.

摘要翻译： 本发明涉及使用干酪乳杆菌制备高纯度人参皂苷Rd的方法，更具体地涉及使用干酪乳杆菌制备高纯度人参皂苷Rd的方法和包含高纯度人参皂甙Rd作为活性物质的抗皱化妆品组合物 成分。 由于本发明的方法简单，并且可以经济地制备高纯度人参皂苷Rd提取物，可以最好地利用人参皂苷Rd的抗皱作用。 此外，通过制备高纯度人参皂苷Rd的水溶性分子胶囊，本发明可以提高稳定性并减少皮肤刺激，从而具有从根本上增加适用性人参皂苷Rd的优点。

公开(公告)号：US06664405B2

公开(公告)日：2003-12-16

申请号：US09996544

申请日：2001-11-28

申请人： Seong Kweon Lee

发明人： Seong Kweon Lee

IPC分类号： C07C5143

CPC分类号： C11C1/007 ,  C11C1/103

摘要： The present invention relates to a method for isolating and purifying only a certain unsaturated fatty acid in a high purity from fatty acids present in oils including vegetable oils and fish oils by means of crystallization. More particularly, the present invention relates to a method for isolating and purifying only the desired unsaturated fatty acid in a high purity from fatty acids present in oils by selectively using a urea-addition crystallization, and a cooling crystallization or a high liquid chromatography. Specifically, the present invention provides a method for isolating and purifying linoleic acid or oleic acid as unsaturated fatty acids, in a high purity of at least 99% by subjecting fatty acids derived from oils, particularly, a vegetable oil containing linoleic acid or oleic acid at a high concentration, such as safflower oil, corn germ oil or olive oil, as the raw material to two-step urea-addition crystallization using methanol and urea and then crystallizing the concentrated unsaturated fatty acid from an organic solvent under cooling at temperature of −5° C. to −10° C. without stirring, or a method for isolating eicosapentaenoic acid (EPA) as unsaturated fatty acid, in a high purity of at least 99% by subjecting fatty acids derived from oils, particularly, a fish oil containing EPA at a high concentration, such as sardine oil, as the raw material to two-step urea-addition crystallization using methanol and urea to obtain a concentrated unsaturated fatty acid having a high purity and then further purifying the high-purified, concentrated fatty acid by means of a high liquid chromatography using a column filled with Ag-silica or Ag-alumina.

公开(公告)号：US07456304B2

公开(公告)日：2008-11-25

申请号：US11388417

申请日：2006-03-24

申请人： Seong Kweon Lee ,  Soon-Kee Sung ,  Sung Soo Kim ,  Jung Kyu Yi

发明人： Seong Kweon Lee ,  Soon-Kee Sung ,  Sung Soo Kim ,  Jung Kyu Yi

IPC分类号： C07C227/00

CPC分类号： C11C3/00 ,  C07C51/412 ,  C07C57/03 ,  C07C57/12

摘要： Disclosed relates to a method for improving a conversion rate of oil soluble unsaturated lipids into water-soluble lipids and, more particularly, to a method for improving a conversion rate of oil soluble unsaturated lipids into water-soluble lipids that forms an unsaturated lipid-chloride derivative having an increased reaction activity by using a pyridine-thionyl chloride as a catalyst, not directly causing a reaction between the unsaturated lipids and amino acids, or that applies an emulsifier to cause a reaction between the unsaturated lipids and amino acids so as to minimize the size of lipid particles to a nano-size of less than 50 nm, thus improving the reaction conversion rate to more than 99%.