公开(公告)号：US20230288421A1

公开(公告)日：2023-09-14

申请号：US18145772

申请日：2022-12-22

申请人： Serimmune Inc.

发明人： Winston A. Haynes ,  Patrick Sean Daugherty ,  Kathryn Vinaya Louise Kamath ,  Jack Ryan Reifert ,  Abhilash Dhal ,  John Chul-yong Shon

IPC分类号： G01N33/569 ,  G01N33/543 ,  C07K7/06

CPC分类号： G01N33/56983 ,  G01N33/54386 ,  G01N33/54326 ,  C07K7/06 ,  G01N2469/20 ,  G01N2333/165

摘要： Disclosed herein are reagents for use in antibody profiling platforms, such as biopanning and Digital Serology, specifically for eptiope motifs directed to SARS-CoV-2. Also disclosed herein are kits, method of manufacturing, and methods of using the same.

公开(公告)号：US20230024898A1

公开(公告)日：2023-01-26

申请号：US17555216

申请日：2021-12-17

申请人： Serimmune Inc.

发明人： John Shon ,  Winston A. Haynes ,  Patrick Sean Daugherty

IPC分类号： G16B30/00 ,  G16B20/30 ,  G16B40/20 ,  G16H70/40

摘要： The present invention provides compositions and methods that can be used to identify an antigen or epitope region of an antigen specific for a disease or other condition. Such methods incorporate k-mer binding statistics to serum antibody from condition and control cohort samples to predict the suitability of antigen sequences identified as relevant to the disease or condition as antigen markers. Also disclosed herein are systems for performing the same.