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公开(公告)号：US10386373B2
公开(公告)日：2019-08-20
申请号：US15991982
申请日：2018-05-29
申请人： SERIMMUNE INC.
IPC分类号： C12N9/10 , G01N33/68 , A61K38/00 , C12Q1/689 , G01N33/558 , C07K14/195 , C07K14/315 , C07K14/285 , C07K14/435 , C07K14/44 , C07K14/45 , C12N15/10
摘要： The present invention provides compositions and methods that can be used to determine a peptide signature for an antibody repertoire in a sample comprising multiple antibodies. The method can be used to characterize a phenotype in a sample, such as providing a diagnosis, prognosis or theranosis of a medical condition.
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公开(公告)号：US20240044911A1
公开(公告)日：2024-02-08
申请号：US18243566
申请日：2023-09-07
申请人： Serimmune Inc.
IPC分类号： G01N33/68 , C07K14/285 , G01N33/53 , C07K14/44 , G01N33/569 , G01N33/564 , C07K14/315 , C07K14/195 , C07K14/45 , C07K14/435
CPC分类号： G01N33/6854 , G01N33/6845 , C07K14/285 , G01N33/53 , C07K14/44 , G01N33/56988 , G01N33/564 , G01N33/56944 , C07K14/315 , C07K14/195 , G01N33/56994 , G01N33/6842 , C07K14/45 , G01N33/56905 , G01N33/6878 , G01N33/56966 , C07K14/43554 , G01N33/56911 , G01N33/56983 , G01N33/569 , G01N2333/18 , G01N2333/095 , C12Q1/689
摘要： The present invention provides compositions and methods that can be used to determine a peptide signature for an antibody repertoire in a sample comprising multiple antibodies. The method can be used to characterize a phenotype in a sample, such as providing a diagnosis, prognosis or theranosis of a medical condition.
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公开(公告)号：US20210230580A1
公开(公告)日：2021-07-29
申请号：US17267004
申请日：2019-08-08
申请人： Serimmune Inc.
IPC分类号： C12N15/10
摘要： Disclosed herein are reagents for use in quality control assessment of antibody profiling platforms, such as biopanning and Digital Serology. Also disclosed herein are kits, method of manufacturing, and methods of using the same.
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公开(公告)号：US20230288421A1
公开(公告)日：2023-09-14
申请号：US18145772
申请日：2022-12-22
申请人： Serimmune Inc.
发明人： Winston A. Haynes , Patrick Sean Daugherty , Kathryn Vinaya Louise Kamath , Jack Ryan Reifert , Abhilash Dhal , John Chul-yong Shon
IPC分类号： G01N33/569 , G01N33/543 , C07K7/06
CPC分类号： G01N33/56983 , G01N33/54386 , G01N33/54326 , C07K7/06 , G01N2469/20 , G01N2333/165
摘要： Disclosed herein are reagents for use in antibody profiling platforms, such as biopanning and Digital Serology, specifically for eptiope motifs directed to SARS-CoV-2. Also disclosed herein are kits, method of manufacturing, and methods of using the same.
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公开(公告)号：US20230024898A1
公开(公告)日：2023-01-26
申请号：US17555216
申请日：2021-12-17
申请人： Serimmune Inc.
摘要： The present invention provides compositions and methods that can be used to identify an antigen or epitope region of an antigen specific for a disease or other condition. Such methods incorporate k-mer binding statistics to serum antibody from condition and control cohort samples to predict the suitability of antigen sequences identified as relevant to the disease or condition as antigen markers. Also disclosed herein are systems for performing the same.
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公开(公告)号：US20230375567A1
公开(公告)日：2023-11-23
申请号：US18122527
申请日：2023-03-16
申请人： Serimmune Inc.
IPC分类号： G01N33/68 , C07K14/195 , C07K14/315 , C07K14/285 , C07K14/435 , C07K14/44 , C07K14/45 , G01N33/569 , G01N33/53 , G01N33/564
CPC分类号： G01N33/6854 , C07K14/195 , C07K14/315 , C07K14/285 , C07K14/43554 , C07K14/44 , C07K14/45 , G01N33/6842 , G01N33/56911 , G01N33/56905 , G01N33/56988 , G01N33/56994 , G01N33/56983 , G01N33/53 , G01N33/56944 , G01N33/564 , G01N33/569 , G01N33/56966 , G01N33/6845 , G01N33/6878 , C12N15/1037
摘要： The present invention provides compositions and methods that can be used to determine a peptide signature for an antibody repertoire in a sample comprising multiple antibodies. The method can be used to characterize a phenotype in a sample, such as providing a diagnosis, prognosis or theranosis of a medical condition.
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公开(公告)号：US20180267056A1
公开(公告)日：2018-09-20
申请号：US15991982
申请日：2018-05-29
申请人： SERIMMUNE INC.
IPC分类号： G01N33/68
CPC分类号： G01N33/6854 , C07K14/195 , C07K14/285 , C07K14/315 , C07K14/43554 , C07K14/44 , C07K14/45 , C12N15/1037 , C12Q1/689 , G01N33/6842 , G01N2800/26 , Y02A50/57
摘要： The present invention provides compositions and methods that can be used to determine a peptide signature for an antibody repertoire in a sample comprising multiple antibodies. The method can be used to characterize a phenotype in a sample, such as providing a diagnosis, prognosis or theranosis of a medical condition.
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公开(公告)号：US11828762B2
公开(公告)日：2023-11-28
申请号：US17096890
申请日：2020-11-12
申请人： Serimmune Inc.
IPC分类号： G01N33/68 , C07K14/195 , C07K14/315 , C07K14/285 , C07K14/435 , C07K14/44 , C07K14/45 , G01N33/569 , G01N33/53 , G01N33/564 , C12N15/10 , C12Q1/689
CPC分类号： G01N33/6854 , C07K14/195 , C07K14/285 , C07K14/315 , C07K14/43554 , C07K14/44 , C07K14/45 , G01N33/53 , G01N33/564 , G01N33/569 , G01N33/56905 , G01N33/56911 , G01N33/56944 , G01N33/56966 , G01N33/56983 , G01N33/56988 , G01N33/56994 , G01N33/6842 , G01N33/6845 , G01N33/6878 , C12N15/1037 , C12Q1/689 , G01N2333/045 , G01N2333/05 , G01N2333/095 , G01N2333/16 , G01N2333/18 , G01N2333/20 , G01N2333/285 , G01N2333/29 , G01N2333/315 , G01N2333/4353 , G01N2570/00 , G01N2800/24 , G01N2800/26 , Y02A50/30
摘要： The present invention provides compositions and methods that can be used to determine a peptide signature for an antibody repertoire in a sample comprising multiple antibodies. The method can be used to characterize a phenotype in a sample, such as providing a diagnosis, prognosis or theranosis of a medical condition.
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公开(公告)号：US20210156873A1
公开(公告)日：2021-05-27
申请号：US17096890
申请日：2020-11-12
申请人： Serimmune Inc.
IPC分类号： G01N33/68 , C07K14/195 , C07K14/315 , C07K14/285 , C07K14/435 , C07K14/44 , C07K14/45 , G01N33/569 , G01N33/53 , G01N33/564
摘要： The present invention provides compositions and methods that can be used to determine a peptide signature for an antibody repertoire in a sample comprising multiple antibodies. The method can be used to characterize a phenotype in a sample, such as providing a diagnosis, prognosis or theranosis of a medical condition.
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