公开(公告)号：US20110092800A1

公开(公告)日：2011-04-21

申请号：US12707197

申请日：2010-02-17

申请人： Seung-Schik Yoo ,  Alexander Bystrisky ,  Nathan McDannold ,  Ferenc A. Jolesz

发明人： Seung-Schik Yoo ,  Alexander Bystrisky ,  Nathan McDannold ,  Ferenc A. Jolesz

IPC分类号： A61N7/00 ,  A61B5/055

CPC分类号： A61B5/4836 ,  A61B5/0042 ,  A61B5/0476 ,  A61B5/055 ,  A61B6/037 ,  A61B2090/374 ,  A61N7/00 ,  A61N7/02 ,  A61N2007/0021 ,  A61N2007/0026 ,  A61N2007/0078

摘要： A method for modifying neuronal activity in a subject with focused ultrasound pulses (“FUP”) is provided. Such a methods is applicable for research, treatment, and diagnosis of psychiatric, neurological, and neuroendocrine disorders whose biological mechanisms include neuronal circuits in the brain. The application of focused ultrasound pulses is generally via multiple ultrasound transducers that are housed in a cap worn by the subject. The application of FUP at different tone burst duration, total sonication duration, and pulse repetition frequency settings results in either the inducement of either an increase or decrease in neuronal activity.

摘要翻译： 提供了一种用聚焦超声脉冲（“FUP”）修饰受试者神经元活动的方法。 这种方法适用于精神，神经和神经内分泌疾病的研究，治疗和诊断，其生物学机制包括脑中的神经元回路。 聚焦超声波脉冲的应用通常是通过多个超声波换能器来容纳在受试者佩戴的帽中。 FUP在不同色调持续时间，总超声处理持续时间和脉冲重复频率设置中的应用导致神经元活动的增加或减少的诱导。